Patents by Inventor Karolina Corin

Karolina Corin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • WATER SOLUBLE MEMBRANE PROTEINS AND METHODS FOR THE PREPARATION AND USE THEREOF
    Publication number: 20180312562
    Abstract: The present invention is directed to water-soluble membrane proteins, methods for the preparation thereof and methods of use thereof.
    Type: Application
    Filed: July 13, 2018
    Publication date: November 1, 2018
    Inventors: Shuguang Zhang, Alexander Rich, Karolina Corin, Lotta Tolstoy Tegler
  • Water soluble membrane proteins and methods for the preparation and use thereof
    Patent number: 10035837
    Abstract: The present invention is directed to a method of preparing a water-soluble variant of a G-protein coupled receptor (GPCR), the method comprising replacing residues leucine (L), isoleucine (I), valine (V), and phenylalanine (F) in hydrophilic surface ?-helical positions b, c, and f but not positions a, d, e, and g within the 7-transmembrane ?-helical domain of the GPCR with glutamine (Q), threonine (T), threonine (T), and tyrosine (Y), respectively.
    Type: Grant
    Filed: March 23, 2016
    Date of Patent: July 31, 2018
    Assignee: Massachusetts Institute of Technology
    Inventors: Shuguang Zhang, Alexander Rich, Karolina Corin, Lotta Tolstoy Tegler
  • WATER SOLUBLE MEMBRANE PROTEINS AND METHODS FOR THE PREPARATION AND USE THEREOF
    Publication number: 20160264640
    Abstract: The present invention is directed to water-soluble membrane proteins, methods for the preparation thereof and methods of use thereof.
    Type: Application
    Filed: March 23, 2016
    Publication date: September 15, 2016
    Applicant: Massachusetts Institute of Technology
    Inventors: Shuguang Zhang, Alexander Rich, Karolina Corin, Lotta Tolstoy Tegler
  • Methods and apparatus for artificial olfaction
    Patent number: 9377447
    Abstract: In exemplary implementations of this invention, an electronic olfactor determines whether a scent being tested matches the scent of a positive control. The electronic olfactor can perform this scent matching even in a changing olfactory environment, and even if the positive control scent is a combination of hundreds or thousands of different odorants. No prior training is needed, and no attempt is made to identify a single odorant that is unambiguously responsible for a scent. Instead, a computer compares the total scent pattern of a positive control sample with the total scent pattern of a test sample, across a sweep of many permutations of electrical inputs to scent sensors, to try to find any condition under which the total scent patterns do not match. If such a condition cannot be found, then the computer declares a match between the test and target scents.
    Type: Grant
    Filed: July 31, 2015
    Date of Patent: June 28, 2016
    Assignee: Massachusetts Institute of Technology
    Inventors: Andreas Mershin, Asmamaw Wassie, Yael Maguire, David Kong, Shuguang Zhang, Patrick Moran, Karolina Corin
  • Water soluble membrane proteins and methods for the preparation and use thereof
    Patent number: 9309302
    Abstract: The present invention is directed to water-soluble membrane proteins, methods for the preparation thereof and methods of use thereof.
    Type: Grant
    Filed: December 13, 2013
    Date of Patent: April 12, 2016
    Assignee: Massachusetts Institute of Technology
    Inventors: Shuguang Zhang, Alexander Rich, Karolina Corin, Lotta T. Tegler
  • Methods and Apparatus for Artificial Olfaction
    Publication number: 20150362469
    Abstract: In exemplary implementations of this invention, an electronic olfactor determines whether a scent being tested matches the scent of a positive control. The electronic olfactor can perform this scent matching even in a changing olfactory environment, and even if the positive control scent is a combination of hundreds or thousands of different odorants. No prior training is needed, and no attempt is made to identify a single odorant that is unambiguously responsible for a scent. Instead, a computer compares the total scent pattern of a positive control sample with the total scent pattern of a test sample, across a sweep of many permutations of electrical inputs to scent sensors, to try to find any condition under which the total scent patterns do not match. If such a condition cannot be found, then the computer declares a match between the test and target scents.
    Type: Application
    Filed: July 31, 2015
    Publication date: December 17, 2015
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Andreas Mershin, Asmamaw Wassie, Yael Maguire, David Kong, Shuguang Zhang, Patrick Moran, Karolina Corin
  • Methods and apparatus for artificial olfaction
    Patent number: 9140677
    Abstract: In exemplary implementations of this invention, an electronic olfactor determines whether a scent being tested matches the scent of a positive control. The electronic olfactor can perform this scent matching even in a changing olfactory environment, and even if the positive control scent is a combination of hundreds or thousands of different odorants. No prior training is needed, and no attempt is made to identify a single odorant that is unambiguously responsible for a scent. Instead, a computer compares the total scent pattern of a positive control sample with the total scent pattern of a test sample, across a sweep of many permutations of electrical inputs to scent sensors, to try to find any condition under which the total scent patterns do not match. If such a condition cannot be found, then the computer declares a match between the test and target scents.
    Type: Grant
    Filed: August 13, 2013
    Date of Patent: September 22, 2015
    Assignee: Massachusetts Institute of Technology
    Inventors: Andreas Mershin, Asmamaw Wassie, Yael Maguire, David Kong, Shuguang Zhang, Patrick Moran, Karolina Corin
  • Water Soluble Membrane Proteins and Methods for the Preparation and Use Thereof
    Publication number: 20140243277
    Abstract: The present invention is directed to water-soluble membrane proteins, methods for the preparation thereof and methods of use thereof.
    Type: Application
    Filed: December 13, 2013
    Publication date: August 28, 2014
    Applicant: Massachusetts Institute of Technology
    Inventors: Shuguang Zhang, Alexander Rich, Karolina Corin, Lotta T. Tegler
  • Methods and Apparatus for Artificial Olfaction
    Publication number: 20140099729
    Abstract: In exemplary implementations of this invention, an electronic olfactor determines whether a scent being tested matches the scent of a positive control. The electronic olfactor can perform this scent matching even in a changing olfactory environment, and even if the positive control scent is a combination of hundreds or thousands of different odorants. No prior training is needed, and no attempt is made to identify a single odorant that is unambiguously responsible for a scent. Instead, a computer compares the total scent pattern of a positive control sample with the total scent pattern of a test sample, across a sweep of many permutations of electrical inputs to scent sensors, to try to find any condition under which the total scent patterns do not match. If such a condition cannot be found, then the computer declares a match between the test and target scents.
    Type: Application
    Filed: August 13, 2013
    Publication date: April 10, 2014
    Inventors: Andreas Mershin, Asmamaw Wassie, Yael Maguire, David Kong, Shuguang Zhang, Patrick Moran, Karolina Corin
  • Water soluble membrane proteins and methods for the preparation and use thereof
    Patent number: 8637452
    Abstract: The present invention is directed to water-soluble membrane proteins, methods for the preparation thereof and methods of use thereof.
    Type: Grant
    Filed: February 23, 2012
    Date of Patent: January 28, 2014
    Assignee: Massachusetts Institute of Technology
    Inventors: Shuguang Zhang, Alexander Rich, Karolina Corin, Lotta T. Tegler
  • WATER SOLUBLE MEMBRANE PROTEINS AND METHODS FOR THE PREPARATION AND USE THEREOF
    Publication number: 20120252719
    Abstract: The present invention is directed to water-soluble membrane proteins, methods for the preparation thereof and methods of use thereof.
    Type: Application
    Filed: February 23, 2012
    Publication date: October 4, 2012
    Inventors: Shuguang Zhang, Alexander Rich, Karolina Corin, Lotta T. Tegler