Patents by Inventor Karoline Dorsch-Hasler

Karoline Dorsch-Hasler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enhancer for eukaryotic expression systems
    Patent number: 6218140
    Abstract: An enhancer has been located in the upstream region of the major immediate early gene of human cytomegalovirus and has been isolated, which enhancer is more active than that from SV40 and has a wide host cell spectrum. Hence, it is suitable for eukaryotic expression systems wherein it can be incorporated upstream or downstream of the structural gene or of the regulation region.
    Type: Grant
    Filed: November 9, 1994
    Date of Patent: April 17, 2001
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Bernhard Fleckenstein, Walter Schaffner, Frank Weber, Karoline Dorsch-Häsler, Gerhard Jahn, Michael Boshart
  • Enhancer for eukaryotic expression systems
    Patent number: 5849522
    Abstract: An enhancer has been located in the upstream region of the major immediate early gene of human cytomegalovirus and has been isolated, which enhancer is more active than that from SV40 and has a wide host cell spectrum. Hence, it is suitable for eukaryotic expression systems wherein it can be incorporated upstream or downstream of the structural gene or of the regulation region.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: December 15, 1998
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Bernhard Fleckenstein, Walter Schaffner, Frank Weber, Karoline Dorsch-Hasler, Gerhard Jahn, Michael Boshart
  • Deoxyribonucleic acid segment from a virus
    Patent number: 4968615
    Abstract: Deoxyribonucleic acid (DNA) molecules consisting of or recombinant DNA molecules containing transcription enhancers from murine cytomegalovirus (MCMV) which can be used to enhance the transcription of structural genes in eukaryotic cells.
    Type: Grant
    Filed: December 18, 1985
    Date of Patent: November 6, 1990
    Assignee: CIBA-GEIGY Corporation
    Inventors: Ulrich H. Koszinowski, Gunther M. Keil, Karoline Dorsch-Hasler, Walter Schaffner