Patents by Inventor Karoly Buzasi

Karoly Buzasi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5156960
    Abstract: The invention relates to a microbial process for the production of immunosuppressive cyclosporine antibiotic complex or of its components, cyclosporine A, cyclosporine B and cyclosporine C, by the aerobic fermentation of a filamentous fungus strain biosynthesizing the above antibiotic(s) in a nutrient medium containing utilizable carbon and nitrogen sources as well as mineral salts, and by isolating the products formed, which comprises culturing a strain of the novel Tolypocladium varium fungus species producing the cyclosporine antibiotic complex, preferably tolypocladium varium sp. nov. CY/93, deposited at the National Collection of Agricultural and Industrial Microorganisms, Budapest, Hungary under the number NCAIM(P)F 001005, on a nutrient medium containing carbon sources, organic and inorganic nitrogen sources as well as mineral salts, under aerobic conditions, at 25.degree. to 30.degree. C., and, if desired, isolating and purifying the cyclosporine antibiotic complex or its components produced.
    Type: Grant
    Filed: December 20, 1989
    Date of Patent: October 20, 1992
    Assignee: Biogal Gyogyszergyar
    Inventors: Antonia Jekkel nee Bokany, Gabor Ambrus, Eva Toth-Sarudy, Istvan Mihaly, Agota Hulber nee Dobos, Attila Andor, Karoly Albrecht, Kalman Konczol, Valeria Szell, Eva Tomori nee Joszt, Imre Moravcsik, Kalman Polya, Janos Erdei, Lajos Kiss, Bela Makadi, Karoly Nagy, Bela Palotas, Etelka Deli nee Konszky, Karoly Buzasi, Aniko Molnar nee Antal, Gyorgy Santha, Vilma Szaszhegyesi