Patents by Inventor Karoly Lapis

Karoly Lapis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USE OF FERMENTED WHEAT GERM IN THE TREATMENT OF INFLAMMATORY BOWEL DISEASE
    Publication number: 20150374776
    Abstract: The present invention provides a fermented dried material derived from the fermented liquid obtainable by fermenting wheat germ with Saccharomyces cerevisiae in an aqueous medium for use in the treatment of inflammatory bowel disease. Methods of treating and/or preventing an inflammatory bowel disease are also described.
    Type: Application
    Filed: May 18, 2012
    Publication date: December 31, 2015
    Applicant: 3CH LTD
    Inventors: Erzsebet RASO, Karoly LAPIS
  • Antileukemic and immunostimulant peptides
    Patent number: 5041535
    Abstract: The new peptides of the Formulae(1) Glp-Lys-NH.sub.2(2) Glp-Glu-Lys-NH.sub.2(3) Arg-Lys-Glu-NH.sub.2(4) Arg-lys-Asp-NH.sub.2(5) Arg-Lys-Glu-OH(6) Arg-Lys-Gln-OH(7) Leu-Val-Ala-OH(8) Arg-Orn-Asp-Val-NH.sub.2(9) Arg-Orn-Asp-Val-OH(10) Lys-Glu-Lys-Lys-OH(11) Lys-Leu-Lys-Lys-OH(12) Lys-Asp-Leu-Lys-OH(13) Glu-Leu-Val-Ala-OH and(14) Leu-Pro-Ala-Gly-OHand acid addition salts thereof inhibit the proliferation of leukaemic cells and exhibit immunostimulant effect.
    Type: Grant
    Filed: November 20, 1987
    Date of Patent: August 20, 1991
    Assignee: Richter Gedeon Vegyeszeti Gyar Rt.
    Inventors: Olga Nyeki nee Kuprina, Istvan Schon, Lajos Kisfaludy, Laszlo Denes, Gyorgy Hajos, Laszlo Szporny, Bela Szende, Karoly Lapis
  • Nitroso-N-(.beta.-chloro ethyl)-carbamoyl peptides
    Patent number: 4950651
    Abstract: The invention relates to new peptide derivatives of the general Formula I ##STR1## wherein R is a group derived from any oligopeptide by removing a terminal amino group, or--if the oligopeptide comprises a diamino carboxylic acid--the amino group in the .omega.-position, or the terminal and .omega.-amino groups; andstands for the integral number 1 or 2and acid addition slats thereof and a process for the preparation thereof.The new compounds of the general Formula I exhibit antitumor activity.
    Type: Grant
    Filed: April 19, 1985
    Date of Patent: August 21, 1990
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara R.T.
    Inventors: Helga Suli, Kalman Medzihradszky, Hedvig Medzihradszky nee Schweiger, Karoly Lapis, Laszlo Kopper, Andras Jeney
  • Thiazolidinecarboxylic acid derivatives and treatment of liver diseases therewith
    Patent number: 4775675
    Abstract: The invention relates to novel thiazolidine-4(S)-carboxylic acid derivatives of the general formula (I) ##STR1## wherein R.sup.1 stands for an optionally substituted furyl, pyrrolyl, thienyl, benzofuryl, benzopyrrolyl, benzothienyl, phenyl, pyridyl, quinolinyl, isoquinolinyl or indanyl group or a C.sub.1-4 alkyl or C.sub.2-4 alkenyl group optionally substituted by a hydroxyl, carboxyl or halogen fenoxy group,stands for hydrogen, an alkaline metal or an alkaline earth metal atom or an optionally substituted C.sub.1-4 alkyl group or aryl group;R.sup.3 represents hydrogen or an optionally substituted C.sub.1-4 alkyl or acyl group or aryl groupas well as their salts.Further on, the invention relates to pharmaceutical preparations containing these compounds and to a process for preparing these compounds and preparations.The compounds of the invention are useful for treating or preventing liver damages of either natural or experimental origin.
    Type: Grant
    Filed: June 13, 1986
    Date of Patent: October 4, 1988
    Assignee: Biogal Gyogyszergyar
    Inventors: Zoltan Gyorgydeak, Istvan Kovacs, Rezso Bognar, Geza Horvath, Janos Balint, Attila Jakab, Judit Krusper nee Ham, Karoly Lapis, Bela Szende, Ferenc Pusztai, Mariann Fekete nee Huszka, Sandor Jancso, Terezia Mile, Ildiko Mihok nee Borbely, Andras Jenei
  • Synergistic pharmaceutical compositions
    Patent number: 4581348
    Abstract: The present invention relates to synergistic pharmaceutical compositions for the treatment of liver disorders comprising 5-aminoimidazole-4-carboxamide orthophosphate (AICA-phosphate) as active ingredient in association with vitamins, preferably with vitamin B and/or E and optionally with other pharmaceutical excipients.
    Type: Grant
    Filed: July 11, 1984
    Date of Patent: April 8, 1986
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara R.T.
    Inventors: Jozsef Schawartz, Maria Hornyak, Tamas Szuts, Jozsef Lengyel, Karoly Lapis, Janos Feher, Sandor Virag, Gyula Sebestyen, Katalin Kalloy, Katalin Marmarosi
  • Pharmaceutical compositions and process for the preparation of same
    Patent number: 4260595
    Abstract: There are disclosed pharmaceutical compositions comprising at least one cytostatic agent and N.sup..epsilon. -trimethylthyllysin or a pharmaceutically acceptable salt thereof, optionally in association with conventional pharmaceutical carriers and other additives.The new compositions possess a reduced toxicity compared with the cytostatic agents administered alone.
    Type: Grant
    Filed: October 12, 1978
    Date of Patent: April 7, 1981
    Assignee: Richter Gedeon Vegyeszeti Gyar Rt.
    Inventors: Karoly Lapis, Bela Szende, Andreas Jeney, Laszlo Kopper, Karoly Simon, Erno Tyihak, Lajos Kisfaludy, Lajos Kovacs, Gyorgy Dobo