Patents by Inventor Karsten Gülow

Karsten Gülow has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINATION THERAPY OF LYMPHOMA
    Publication number: 20210161851
    Abstract: The present invention relates to an NF-?B inhibitor or a pharmaceutically acceptable salt or prodrug thereof for use in treating lymphoma, wherein said use further comprises administration of at least one agent activating the intrinsic pathway of apoptosis; and to an agent activating the intrinsic pathway of apoptosis or a pharmaceutically acceptable salt or prodrug thereof for use in treating lymphoma, wherein said use further comprises administration of at least one NF-?B inhibitor. The present invention further relates to combined preparations, medicaments, kits, and methods related thereto.
    Type: Application
    Filed: November 30, 2020
    Publication date: June 3, 2021
    Inventors: Tabea Schlör, Jan Nicolay, Peter Krammer, Karsten Gülow
  • Inhibitors of thioredoxin-interacting protein (TXNIP) for therapy
    Publication number: 20170002352
    Abstract: Described is a compound capable of reducing or inhibiting (a) the biological activity of thioredoxin-interacting protein (TXNIP) or (b) the expression of the gene encoding TXNIP for treating a condition where improving the resistance towards oxidative stress has a beneficial effect, e.g., for improving female fertiliy or extending healthy lifespan.
    Type: Application
    Filed: July 25, 2016
    Publication date: January 5, 2017
    Inventors: Peter KRAMMER, Karsten GÜLOW, Sabine ZIOLA
  • Inhibitors of thioredoxin-interacting protein (TXNIP) for therapy
    Publication number: 20150152169
    Abstract: Described is a compound capable of reducing or inhibiting (a) the biological activity of thioredoxin-interacting protein (TXNIP) or (b) the expression of the gene encoding TXNIP for treating a condition where improving the resistance towards oxidative stress has a beneficial effect, e.g., for improving female fertiliy or extending healthy lifespan.
    Type: Application
    Filed: April 17, 2013
    Publication date: June 4, 2015
    Applicant: DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES ÖFFENTLICHEN RECHTES
    Inventors: Peter Krammer, Karsten Gülow, Sabine Sass
  • Methods and compounds for treating diseases caused by reactive oxygen species
    Patent number: 8563500
    Abstract: Provided is a method of treating a patient having an inflammatory disease by using a compound which inhibits the complex I-mediated ROS production, a medicament containing such compound and methods for screening for such compounds.
    Type: Grant
    Filed: September 5, 2007
    Date of Patent: October 22, 2013
    Assignee: Deutsches Krebsforschungszentrum Stiftung des Offentlichen Rechts
    Inventors: Karsten Guelow, Marcin Kaminski, Michael Kiessling, Peter H. Krammer
  • FLUOROQUINOLONES FOR THE TREATMENT AND/OR PROPHYLAXIS OF INFLAMMATORY DISEASES
    Publication number: 20130079353
    Abstract: The present invention relates to a pharmaceutical composition comprising at least one compound of formula (I) wherein R1 denotes e.g. hydrogen or straight chain C1-C6-alkyl, R2 and R3 denote e.g. hydrogen or straight chain C1-C6-alkyl, or a pharmaceutically acceptable salt thereof and at least one pharmaceutically acceptable excipient for use as a medicament for the treatment of inflammatory diseases or conditions, in particular T-cell mediated inflammatory diseases or conditions.
    Type: Application
    Filed: December 20, 2010
    Publication date: March 28, 2013
    Inventors: Karsten Gülow, Marcin M. Kaminski, H. Peter Krammer
  • METHODS AND COMPOUNDS FOR TREATING DISEASES CAUSED BY REACTIVE OXYGEN SPECIES
    Publication number: 20100305187
    Abstract: Provided is a method of treating a patient having an inflammatory disease by using a compound which inhibits the complex I-mediated ROS production, a medicament containing such compound and methods for screening for such compounds.
    Type: Application
    Filed: September 5, 2007
    Publication date: December 2, 2010
    Applicant: Deutsches Krebsforschungszentrum Stiftung des offentlichen Rechts
    Inventors: Karsten Guelow, Marcin Kaminski, Michael Kiessling, Peter H. Krammer