Abstract: It is provided a method for generating a supercontinuum, the method comprising the following steps: a) radiating a carrier laser pulse having a first temporal width onto a first non-linear material; b) at the same time, radiating a second shorter laser pulse having a second temporal width onto the first non-linear material, thereby changing the non-linear properties of the first non-linear material and imprinting a ghost pulse having a third temporal width into the carrier pulse; the second temporal width being at least two times shorter than the first temporal width, and c) radiating the carrier pulse with imprinted ghost pulse onto the first non-linear material or a second non-linear material and generating, by self-phase modulating, a supercontinuum around the center frequency of the carrier pulse.

Abstract: A method for the infrared-light-induced yield optimization of chemical reactions is provided. An energy input into at least one starting material that is subjected to a chemical reaction takes place by means of infrared light pulses having a mean wavelength in the range of 2000 to 100000 nm. The chemical reaction here is a reaction in which a product, the molecular formula of which does not correspond to the molecular formula of the starting material, is formed and wherein the yield optimization for the most part is not based on a thermal heating of the starting material. The infrared light pulses have a fixed wavelength and the energy input into the starting material takes place by means of vibration excitation by a one-photon process.

Abstract: The disclosure relates to a method for providing original data that can be used for subsequently determining the function of an organ of a living organism or for subsequently diagnosing a disease or a severity of a disease of an organ of a living organism. This method is characterized by several steps, one of which is administering a marker substance to a living organism by inhalation, wherein the marker substance has a vapor pressure above 0.01 mmHg at 37° C. In other method steps, the concentration of this marker substance in exhaled air is determined at at least two different time points. Then, a difference in marker substance concentration is calculated.

Abstract: A method for controlling the emission frequency of a laser comprises: recording a first spectrum by passing a laser light emitted by the laser through a sample onto a detector, the detector being connected to a multichannel analyzer which assigns pulses detected by the detector to a channel; determining a first channel to which the maximum of a first signal in the first spectrum has been assigned; determining a second channel to which the maximum of a second signal in the first spectrum has been assigned; recording a second spectrum in analog fashion like the first spectrum; determining whether the maximum of the first signal in the second spectrum has been assigned to the first channel and whether the maximum of the second signal in the second spectrum has been assigned to the second channel; adjusting the operating temperature of the laser in the event of deviations determined in the previous step.

Abstract: The invention relates to a method for the infrared-light-induced yield optimization of chemical reactions, wherein an energy input into at least one starting material that is subjected to a chemical reaction takes place by means of infrared light pulses having a mean wavelength in the range of 2000 to 100000 nm. The chemical reaction here is a reaction in which a product, the molecular formula of which does not correspond to the molecular formula of the starting material, is formed and wherein the yield optimization for the most part is not based on a thermal heating of the starting material. The invention is characterized in that the infrared light pulses have a fixed wavelength and in that the energy input into the starting material takes place by means of vibration excitation by a one-photon process.

Abstract: A method for controlling the emission frequency of a laser comprises: recording a first spectrum by passing a laser light emitted by the laser through a sample onto a detector, the detector being connected to a multichannel analyzer which assigns pulses detected by the detector to a channel; determining a first channel to which the maximum of a first signal in the first spectrum has been assigned; determining a second channel to which the maximum of a second signal in the first spectrum has been assigned; recording a second spectrum in analog fashion like the first spectrum; determining whether the maximum of the first signal in the second spectrum has been assigned to the first channel and whether the maximum of the second signal in the second spectrum has been assigned to the second channel; adjusting the operating temperature of the laser in the event of deviations determined in the previous step.

Abstract: A method for the infrared-light-induced yield optimization of chemical reactions is provided. An energy input into at least one starting material that is subjected to a chemical reaction takes place by means of infrared light pulses having a mean wavelength in the range of 2000 to 100000 nm. The chemical reaction here is a reaction in which a product, the molecular formula of which does not correspond to the molecular formula of the starting material, is formed and wherein the yield optimization for the most part is not based on a thermal heating of the starting material. The infrared light pulses have a fixed wavelength and the energy input into the starting material takes place by means of vibration excitation by a one-photon process.

Abstract: The disclosure relates to a method for providing original data that can be used for subsequently determining the function of an organ of a living organism or for subsequently diagnosing a disease or a severity of a disease of an organ of a living organism. This method is characterized by several steps, one of which is administering a marker substance to a living organism by inhalation, wherein the marker substance has a vapor pressure above 0.01 mmHg at 37° C. In other method steps, the concentration of this marker substance in exhaled air is determined at at least two different time points. Then, a difference in marker substance concentration is calculated.

Abstract: A method for polymerizing monomer units and/or oligomer units is disclosed. Said method is characterized in that the energy required for polymerization is introduced into the monomer units and/or oligomer units to be polymerized by means of infrared light pulses, wherein the infrared light pulses have a wavelength of 2500 to 20000 nm, an intensity of more than 1014 W/m2, a duration of more than 8 fs and less than 3 ps and a substantially linear polarization.

Abstract: A method for determining the temperature of an infrared-active gas by means of infrared spectroscopy is provided. The method comprising: radiating infrared light in a spectral range of 700 cm?1 to 5000 cm?1 originating from an infrared light source onto the gas; obtaining a first absorption-related parameter originating from measuring a first infrared absorption band of the gas, wherein the first infrared absorption band is a hot band being caused by thermal population of at least one vibrational mode of the gas; obtaining a second absorption-related parameter originating from measuring a second infrared absorption band of the gas, and calculating a ratio between the first absorption-related parameter and the second absorption-related parameter. The method is characterized in that the ratio is used to determine the temperature of the gas, wherein the ratio has a relative change of at least 0.5% per Kelvin temperature difference of the gas.

Abstract: A method for determining the metabolic capacity of an enzyme includes time-resolved determination of the concentration of a product in exhaled air. The product is created by metabolism of a substrate, previously administered to an individual, by an enzyme of the individual. The product concentration is determined until the maximum product concentration in the exhaled air is reached. A model function is fitted to measured values of the product concentration, obtained by the time-resolved determination of the product concentration between start and end times. The metabolic capacity of the enzyme is determined based on parameters of the model function. Determining the metabolic capacity of the enzyme takes place based on at least two parameters of the model function, wherein the maximum value and time constant of the model function are not selected as parameters at the same time, and the start and/or end times are not selected as parameters.

Abstract: A measurement device and a method for analyzing a sample gas by infrared absorption spectroscopy are described. The measurement device comprises a narrowband laser having a line width of less than 0.2 cm?1 and being smaller than a width of an infrared absorption line to be measured of a sample gas. The measurement device is suited and can be arranged to measure the respiratory gas of a human or animal as sample gas, wherein the respiratory gas exchanges in the measurement chamber only by the respiration of the human or animal, and the respiratory resistance of the measurement device is less than 60 mbar.

Abstract: The invention relates to a method for the infrared-light-induced yield optimization of chemical reactions, wherein an energy input into at least one starting material that is subjected to a chemical reaction takes place by means of infrared light pulses having a mean wavelength in the range of 2000 to 100000 nm. The chemical reaction here is a reaction in which a product, the molecular formula of which does not correspond to the molecular formula of the starting material, is formed and wherein the yield optimization for the most part is not based on a thermal heating of the starting material. The invention is characterized in that the infrared light pulses have a fixed wavelength and in that the energy input into the starting material takes place by means of vibration excitation by a one-photon process.

Abstract: A laser pulse shaping method is configured for microscopically viewing and modifying an object. A temporal modulation and a two-dimensional spatial modulation of laser pulses are carried out. At least the phase of the laser pulses is modulated dependent on the location, and the modulated laser pulses are directed at the object.

Abstract: A method for polymerizing monomer units and/or oligomer units is disclosed. Said method is characterized in that the energy required for polymerization is introduced into the monomer units and/or oligomer units to be polymerized by means of infrared light pulses, wherein the infrared light pulses have a wavelength of 2500 to 20000 nm, an intensity of more than 1014 W/m2, a duration of more than 8 fs and less than 3 ps and a substantially linear polarization.

Abstract: A method for determining the metabolic capacity of an enzyme includes time-resolved determination of the concentration of a product in exhaled air. The product is created by metabolism of a substrate, previously administered to an individual, by an enzyme of the individual. The product concentration is determined until the maximum product concentration in the exhaled air is reached. A model function is fitted to measured values of the product concentration, obtained by the time-resolved determination of the product concentration between start and end times. The metabolic capacity of the enzyme is determined based on parameters of the model function. Determining the metabolic capacity of the enzyme takes place based on at least two parameters of the model function, wherein the maximum value and time constant of the model function are not selected as parameters at the same time, and the start and/or end times are not selected as parameters.

Abstract: A pulse shaper for compensating group runtime effects is provided. The pulse shaper comprising a first and a second dispersive element. An optical pulse can be coupled to the pulse shaper along a coupling direction such that said pulse exits from the pulse shaper after passing through the first and the second dispersive element along an exit direction. The first and the second dispersive element are formed and arranged to be movable relative to each other such that the path length to be traversed by the optical pulse through the first and the second dispersive element after coupling to the pulse shaper can be adjusted without any change in an offset between the coupling direction and the exit direction. The first and the second dispersive element are arranged in such a way that the shape of the optical pulse experiences a change as the pulse travels through the pulse shaper.

Abstract: A method for determining the 14C content of a gas mixture in which 14C isotopes are present as molecule constituents, is provided. The gas mixture is provided in a measuring space, wherein infrared laser radiation is supplied to the measuring space as measurement radiation. The laser radiation to be supplied to the measuring space is deflected such that it passes through the measuring space a plurality of times by interacting with the gas mixture, wherein the laser radiation is supplied to a detector, in order to determine the absorption of laser radiation by the gas mixture and therefrom determine the 14C content. For generating the laser radiation a pulsed laser is used, which as measurement radiation emits laser pulses with a pulse duration of less than 5 ?s, which are supplied to the measuring space.

Abstract: A method for determining the liver performance of a living organism, in particular a human, comprising administering at least one 13C labelled substrate, which is converted by the liver by releasing at least one 13C labelled metabolization product, and determining the amount of the at least one 13C labelled metabolization product in the exhalation air over a definite time interval by the means of at least one measuring device with at least one evaluation unit is disclosed. Using this method, it is possible to describe the measured initial increase of the amount of the at least one 13C labelled metabolization product in the exhalation air using a differential equation of first order and to determine a value Amax (DOBmax) and a time constant tau of the increase of the amount of 13C labelled metabolization product from the solution of the differential equation of first order.

Abstract: A measurement device and a method for analyzing a sample gas by infrared absorption spectroscopy are described. The measurement device comprises: a measurement chamber with the sample gas to be analyzed, a laser being arranged in relation to the measurement chamber such that light being emitted from the laser radiates through the measurement chamber, a detection device detecting the light being emitted from the laser and radiated through the measurement chamber, and an evaluation unit evaluating signals generated by the detection device regarding a light absorption occurred in the measurement chamber.