Abstract: Lysyl oxidase (LOX) inhibitors, lysyl oxidase-like (LOXL) inhibitors, or pharmaceutically acceptable salts thereof and methods for the treatment of myeloid malignancies, comprising administering a therapeutically effective amount of those inhibitors alone or optionally in combination with a second therapeutic agent.

Abstract: The present invention relates to a method for the detection of the presence or absence of at least one nucleic acid sequence specific for the sex of chicken using polymerase chain reaction in a high-throughput manner, a kit for conducting the method of the present invention and a pair of oligonucleotides.

Abstract: The present invention relates to a method for the detection of the presence or absence of at least one nucleic acid sequence specific for the sex of chicken using polymerase chain reaction in a high-throughput manner, a kit for conducting the method of the present invention and a pair of oligonucleotides.

Abstract: The present disclosure relates to automobiles and, more specifically, teaches methods and systems that may be used for wirelessly charging batteries used in vehicles. In one embodiment, a method for detecting a relative position between a vehicle-side receiving charging coil and a fixed transmission charging coil, may include: generating an alternating magnetic orientation field using one of the coils; detecting the orientation field using at least one coil provided for inductive excitation, wherein the orientation field is detected in a frequency-selective manner by the at least one coil; and ascertaining the relative position using an orientation receiving signal induced by the orientation field in the at least one coil.

Abstract: At least one laser line is projected onto a surface of a patient located on a patient table, and is detected. An evaluation and control apparatus determines initial coordinate points along a laser line projected onto the surface of the patient during an initial radiation procedure based on measurement values associated with the at least one laser line detected through an initial real-time triangulation process. The initial coordinate points are compared with target coordinate points for patient positioning. Whether or not an impermissible deviation exists between the initial coordinate points and the target coordinate points is determined, and a corrective action is executed based on the determination that an impermissible deviation exists. Determining updated coordinate points occurs while corrective action is being executed, and a warning signal is emitted based on the updated coordinate points.

Abstract: A system and method for determining the position of objects in a radiation room for radiation therapy comprises several room lasers arranged in the radiation room, each of which is designed for patient positioning to project at least one laser line onto the surface of a patient located on a patient table in the radiation room. At least one camera detects at least one laser line projected onto the surface of the patient by at least one of the room lasers, and an evaluation and control apparatus determines the coordinate points along the laser line projected onto the surface of patient during a radiation procedure based on measurement values detected by the camera through a real-time triangulation process and compares them with target coordinate points. The coordinate points determined during the radiation procedure may be saved for documentation of the radiation procedure.

Abstract: The present disclosure relates to automobiles and, more specifically, teaches methods and systems that may be used for wirelessly charging batteries used in vehicles. In one embodiment, a method for detecting a relative position between a vehicle-side receiving charging coil and a fixed transmission charging coil, may include: generating an alternating magnetic orientation field using one of the coils; detecting the orientation field using at least one coil provided for inductive excitation, wherein the orientation field is detected in a frequency-selective manner by the at least one coil; and ascertaining the relative position using an orientation receiving signal induced by the orientation field in the at least one coil.

Abstract: A method is provided for determining at least one operating parameter of a thermoelectric system in a vehicle, wherein the thermoelectric system comprises an energy conversion device having at least one photovoltaic element for converting thermal radiation, which is emitted by a heat source of the vehicle, into electrical energy. The method includes measuring an electrical power of the photovoltaic device, and determining an operating parameter of the thermoelectric system based on the measured electrical power of the photovoltaic device.

Abstract: A method is disclosed for distributing energy in an electric vehicle including at least one electric energy store and at least one conditioning module, which can be used to generate electric energy from fuel, as energy sources, wherein driving-related information, or information about a state of the electric vehicle, is recorded before driving, or when beginning to drive, the electric vehicle and, while driving, energy is distributed in the vehicle on the basis of the information.

Abstract: A system and method for determining the position of objects in a radiation room for radiation therapy comprises several room lasers arranged in the radiation room, each of which is designed for patient positioning to project at least one laser line onto the surface of a patient located on a patient table in the radiation room. At least one camera detects at least one laser line projected onto the surface of the patient by at least one of the room lasers, and an evaluation and control apparatus determines the coordinate points along the laser line projected onto the surface of patient during a radiation procedure based on measurement values detected by the camera through a real-time triangulation process and compares them with target coordinate points. The coordinate points determined during the radiation procedure may be saved for documentation of the radiation procedure.

Abstract: A method is disclosed for distributing energy in an electric vehicle including at least one electric energy store and at least one conditioning module, which can be used to generate electric energy from fuel, as energy sources, wherein driving-related information, or information about a state of the electric vehicle, is recorded before driving, or when beginning to drive, the electric vehicle and, while driving, energy is distributed in the vehicle on the basis of the information.

Abstract: A method is provided for determining at least one operating parameter of a thermoelectric system in a vehicle, wherein the thermoelectric system comprises an energy conversion device having at least one photovoltaic element for converting thermal radiation, which is emitted by a heat source of the vehicle, into electrical energy. The method includes measuring an electrical power of the photovoltaic device, and determining an operating parameter of the thermoelectric system based on the measured electrical power of the photovoltaic device.

Abstract: A medical device having a silane surface comprising an antimicrobial peptide exhibiting a complex tertiary structure, wherein the antimicrobial peptide is attached to the silane surface via reversible interaction.

Abstract: The present invention relates to isolated polypeptides which comprise an amino acid sequence consisting of a mutated functional Abl kinase domain, said mutated functional kinase domain being resistant to inhibition of its tyrosine kinase activity by N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-4-(4-methyl-piperazin-1-ylmethyl)-benzamide or a salt thereof, to the use of such polypeptides to screen for compounds which inhibit the tyrosine kinase activity of such polypeptides, to nucleic acid molecules encoding such polypeptides, to recombinant vectors and host cells comprising such nucleic acid molecules and to the use of such nucleic acid molecules in the production of such polypeptides for use in screening for compounds which inhibit the tyrosine kinase activity of such polypeptides.

Abstract: Presented is an apparatus that includes a vehicle component that includes an outer wall that includes an internal face and at least one electro-acoustic transducer disposed on the internal face of the outer wall of the vehicle component. The at least one electro-acoustic transducer includes a pot-type housing and a piezo-electric ceramic body disposed inside the pot-type housing. The pot-type housing includes a base area affixed to the internal face of the outer wall of the vehicle component.

Abstract: The present invention relates to isolated polypeptides which comprise an amino acid sequence consisting of a mutated functional Abl kinase domain, said mutated functional kinase domain being resistant to inhibition of its tyrosine kinase activity by N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-4-(4-methyl-piperazin-1 -ylmethyl)-benzamide or a salt thereof, to the use of such polypeptides to screen for compounds which inhibit the tyrosine kinase activity of such polypeptides, to nucleic acid molecules encoding such polypeptides, to recombinant vectors and host cells comprising such nucleic acid molecules and to the use of such nucleic acid molecules in the production of such polypeptides for use in screening for compounds which inhibit the tyrosine kinase activity of such polypeptides.

Abstract: A method of displaying an image on a work piece positioned on a movable work surface. A method of processing a work piece, as well as a method of displaying an image on a moveable work surface, is also provided. A system for machining a work piece in accordance with one or more images projected onto the work piece is also provided.

Abstract: The tides which comprise an amino acid sequence consisting of a mutated functional Abl kinase domain, said mutated functional kinase domain being resistant to inhibition of its tyrosine kinase activity by N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-4-(4-methyl-piperazin-1-ylmethyl)-benzamide or a salt thereof, to the use of such polypeptides to screen for compounds which inhibit they tyrosine kinase activity of such polypeptides, to nucleic acid molecules encoding such polypeptides, to recombinant vectors and host cells comprising such nucleic acid molecules and to the use of such nucleic molecules in the production of such polypeptides for use in screening for compounds which inhibit the tyrosine kinase activity of such polypeptides.

Abstract: A method of displaying an image on a work piece positioned on a movable work surface. A method of processing a work piece, as well as a method of displaying an image on a moveable work surface, is also provided. A system for machining a work piece in accordance with one or more images projected onto the work piece is also provided.

Abstract: The present invention relates to isolated polypeptides which comprise an amino acid sequence consisting of a mutated functional Abl kinase domain, said mutated functional kinase domain being resistant to inhibition of its tyrosine kinase activity by N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-4-(4-methyl-piperazin-1-ylmethyl)-benzamide or a salt thereof, to the use of such polypeptides to screen for compounds which inhibit the tyrosine kinase activity of such polypeptides, to nucleic acid molecules encoding such polypeptides, to recombinant vectors and host cells comprising such nucleic acid molecules and to the use of such nucleic acid molecules in the production of such polypeptides for use in screening for compounds which inhibit the tyrosine kinase activity of such polypeptides.