Patents by Inventor Karsten M. Kragh
Karsten M. Kragh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8986970Abstract: The present compositions and methods relate to an endo-?-mannanase cloned from Bacillus agaradhaerens, polynucleotides encoding the endo-?-mannanase, and methods of use thereof. Formulations containing the endo-?-mannanase are highly suitable for use as detergents.Type: GrantFiled: July 1, 2014Date of Patent: March 24, 2015Assignee: Danisco US Inc.Inventors: Brian E. Jones, Marc Kolkman, Zhen Qian, Brian Sogaard Laursen, Karsten M. Kragh, Sina Pricelius, Zheyong Yu, Lilia Maria Babe, Melodie Estabrook
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Publication number: 20150017700Abstract: The present invention provides lipolytic enzyme variants. Specifically, the present invention provides lipolytic enzyme variants having two, three, or more modifications as compared to a parent lipolytic enzyme having at least one improved property. In addition, the present invention provides compositions comprising a lipolytic enzyme variant of the invention. The present invention also provides methods of cleaning using compositions comprising a lipolytic enzyme variant of the invention.Type: ApplicationFiled: December 20, 2012Publication date: January 15, 2015Inventors: David A. Estell, Thomas P. Graycar, Lene Bojsen Jensen, Anja Hemmingsen Kellett-Smith, Karsten M. Kragh, Rie Mejldal, Sina Pricelius, Jian Yao
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Publication number: 20140377841Abstract: The present compositions and methods relate to an endo-?-mannanase cloned from Bacillus agaradhaerens, polynucleotides encoding the endo-?-mannanase, and methods of use thereof. Formulations containing the endo-?-mannanase are highly suitable for use as detergents.Type: ApplicationFiled: July 1, 2014Publication date: December 25, 2014Applicant: DANISCO US INC.Inventors: Brian E. Jones, Marc Kolkman, Zhen Qian, Brian Sogaard Laursen, Karsten M. Kragh, Sina Pricelius, Zheyong Yu, Lilia Maria Babe, Melodie Estabrook
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Patent number: 8802388Abstract: The present compositions and methods relate to an endo-?-mannanase cloned from Bacillus agaradhaerens, polynucleotides encoding the endo-?-mannanase, and methods of use thereof. Formulations containing the endo-?-mannanase are highly suitable for use as detergents.Type: GrantFiled: April 27, 2012Date of Patent: August 12, 2014Assignee: Danisco US Inc.Inventors: Brian E. Jones, Marc Kolkman, Zhen Qian, Brian Sogaard Laursen, Karsten M. Kragh, Sina Pricelius, Zheyong Yu, Lilia Maria Babe, Melodie Estabrook
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Publication number: 20140187468Abstract: The present invention provides lipolytic enzyme variants. Specifically, the present invention provides lipolytic enzyme variants having one or more modifications as compared to a parent lipolytic enzyme having at least one improved property. In addition, the present invention provides compositions comprising a lipolytic enzyme variant of the invention. The present invention also provides methods of cleaning using compositions comprising a lipolytic enzyme variant of the invention.Type: ApplicationFiled: August 30, 2012Publication date: July 3, 2014Applicant: DANISCO US INC.Inventors: David A. Estell, Lene Bojsen Jensen, Karsten M. Kragh, Rie Mejldal, Sina Pricelius
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Publication number: 20140135252Abstract: The present compositions and methods relate to an endo-B-mannanase cloned from Geobacillus tepidamans, polynucleotides encoding the endo-B-mannanase, and methods of use thereof. Formulations containing the endo-?-mannanase are highly suitable for use as detergents.Type: ApplicationFiled: April 27, 2012Publication date: May 15, 2014Applicant: Danisco US Inc.Inventors: Brian E. Jones, Marc Kolkman, Zhen Qian, Brian Sogaard Laursen, Karsten M. Kragh, Sina Pricelius, Zheyong Yu, Lilia Maria Babe, Melodie Estabrook, Ling Hua
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Publication number: 20140073030Abstract: The present compositions and methods relate to an endo-?-mannanase cloned from Bacillus agaradhaerens, polynucleotides encoding the endo-?-mannanase, and methods of use thereof. Formulations containing the endo-?-mannanase are highly suitable for use as detergents.Type: ApplicationFiled: April 27, 2012Publication date: March 13, 2014Applicant: Danisco US Inc.Inventors: Brian E. Jones, Marc Kolkman, Zhen Qian, Brian Sogaard Laursen, Karsten M. Kragh, Sina Pricelius, Zheyong Yu, Lilian Maria Babe, Melodie Estabrook
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Publication number: 20140073548Abstract: The present compositions and methods relate to an endo-B-mannanase cloned from a Bacillus sp., polynucleotides encoding the endo-B-mannanase, and methods of use thereof. Formulations containing the endo-?-mannanase are highly suitable for use as detergents.Type: ApplicationFiled: April 27, 2012Publication date: March 13, 2014Applicant: Danisco US Inc.Inventors: Brian E. Jones, Marc Kolkman, Zhen Qian, Brian Sogaard Laursen, Karsten M. Kragh, Sina Pricelius, Zheyong Yu, Lilia Maria Babe, Melodie Estabrook, Ling Hua
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Patent number: 8318451Abstract: Pseudomonas saccharophila G4-forming amylase (PS4), and variants thereof, advantageously can be used in an enzyme-catalyzed high temperature liquefaction step to produce ethanol from starch, e.g., cornstarch. PS4 produces significant amounts of maltotrioses, which can be utilized by S. cerevisiae in a subsequent fermentation step to produce ethanol. This property of PS4 advantageously allows ethanol to be produced from liquefacted starch in the absence of a saccharification step. PS4 variants are provided that exhibit improved properties, such as thermostability and/or altered exo-specific and endo-specific amylase activity.Type: GrantFiled: December 30, 2008Date of Patent: November 27, 2012Assignee: Danisco US Inc.Inventors: Andrew Shaw, Regina Chin, Karsten M. Kragh
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Publication number: 20120252101Abstract: Variants of Bacillus sp. TS-23 strain alpha-amylases exhibit improved enzymatic performance, including increased themostability, reduced calcium dependence, increased washing/cleaning performance, and baking ability. Compositions comprising these variants are useful in methods of starch processing, starch liquefaction, fermatation, starch saccharification, cleaning, laundrying, textile desizing, baking, and biofilm removal.Type: ApplicationFiled: March 2, 2012Publication date: October 4, 2012Applicant: Danisco US Inc.Inventors: Claudine Y. Chang, Clement Choy, Melodie Estabrook, Mansi Goyal, Thomas P. Graycar, Victoria E. Huang, Brian E. Jones, Marc Kolkman, Karsten M. Kragh, Chris Leeflang, Scott D. Power, Sandra W. Ramer, Andrew SHAW, Casper Vroemen, Walter Weyler
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Patent number: 8153412Abstract: Variants of Bacillus sp. TS-23 strain alpha-amylases exhibit improved enzymatic performance, including increased themostability, reduced calcium dependence, increased washing/cleaning performance, and baking ability. Compositions comprising these variants are useful in methods of starch processing, starch liquefaction, fermatation, starch saccharification, cleaning, laundrying, textile desizing, baking, and biofilm removal.Type: GrantFiled: November 3, 2008Date of Patent: April 10, 2012Assignee: Danisco US Inc.Inventors: Claudine Y. Chang, Clement Choy, Melodie Estabrook, Mansi Goyal, Thomas P. Graycar, Victoria E. Huang, Brian E. Jones, Marc Kolkman, Karsten M. Kragh, Chris Leeflang, Scott D. Power, Sandra W. Ramer, Andrew Shaw, Casper Vroemen, Walter Weyler
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Patent number: 7803598Abstract: An enzyme is described which enzyme is derived from family 13 of ?-amylases. The enzyme variant is obtainable by modifying a CGTase or a maltogenic ?-amylase. The enzyme is useful in preparing a food or a food product such as bakery products.Type: GrantFiled: September 12, 2005Date of Patent: September 28, 2010Assignee: Danisco A/SInventors: Karsten M. Kragh, Hans Leemhuis, Lubbert Dijkhuizen, Bauke W. Dijkstra
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Publication number: 20100021587Abstract: Variants of Bacillus sp. TS-23 strain alpha-amylases exhibit improved enzymatic performance, including increased themostability, reduced calcium dependence, increased washing/cleaning performance, and baking ability. Compositions comprising these variants are useful in methods of starch processing, starch liquefaction, fermatation, starch saccharification, cleaning, laundrying, textile desizing, baking, and biofilm removal.Type: ApplicationFiled: November 3, 2008Publication date: January 28, 2010Applicant: Danisco US Inc., Genencor DivisionInventors: CLAUDINE Y. CHANG, CLEMENT CHOY, MELODIE ESTABROOK, MANSI GOYAL, THOMAS P. GRAYCAR, VICTORIA E. HUANG, BRIAN E. JONES, MARC KOLKMAN, KARSTEN M. KRAGH, CHRIS LEEFLANG, SCOTT D. POWER, SANDRA W. RAMER, ANDREW SHAW, CASPER VROEMEN, WALTER WEYLER
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Publication number: 20090311764Abstract: Pseudomonas saccharophila G4-forming amylase (PS4), and variants thereof, advantageously can be used in an enzyme-catalyzed high temperature liquefaction step to produce ethanol from starch, e.g., cornstarch. PS4 produces significant amounts of maltotrioses, which can be utilized by S. cerevisiae in a subsequent fermentation step to produce ethanol. This property of PS4 advantageously allows ethanol to be produced from liquefacted starch in the absence of a saccharification step. PS4 variants are provided that exhibit improved properties, such as thermostability and/or altered exo-specific and endo-specific amylase activity.Type: ApplicationFiled: December 30, 2008Publication date: December 17, 2009Applicant: Danisco US Inc., Genencor DivisionInventors: Andrew Shaw, Regina Chin, Karsten M. Kragh
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Patent number: 6890572Abstract: The present invention relates to the use of non-maltogenic exoamylases of retarding the detrimental retrogradation of starch. Furthermore, the invention relates to a novel non-maltogenic exoamylase from Bacillus Clausii.Type: GrantFiled: September 25, 2003Date of Patent: May 10, 2005Assignee: Danisco A/SInventors: Karsten M. Kragh, Bjarne Larsen, Preben Rasmussen, Lene Duedahl-Olesen, Wolfgang Zimmermann
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Publication number: 20040043109Abstract: The present invention relates to the use of non-maltogenic exoamylases of retarding the detrimental retrogradation of starch. Furthermore, the invention relates to a novel non-maltogenic exoamylase from Bacillus Clausii.Type: ApplicationFiled: September 25, 2003Publication date: March 4, 2004Applicant: Danisco A/SInventors: Karsten M. Kragh, Bjarne Larsen, Preben Rasmussen, Lene Duedahl-Olesen, Wolfgang Zimmermann
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Patent number: 6667065Abstract: The present invention relates to a process for making a bread product. The process includes the addition of a non-maltogenic exoamylase that hydrolyses starch to a starch medium, and the application of heat to the starch medium. The non-maltogenic exomylase cleaves one or more linear malto-oligosaccharides, predominantly consisting of from four to eight D-glucopyranosyl units, from non-reducing ends of amylopectin side chains. The non-maltogenic exoamylase has an endoamylase activity of less than 0.5 endoamylase units (EAU) per unit of exoamylase activity.Type: GrantFiled: February 28, 2001Date of Patent: December 23, 2003Assignee: Danisco A/SInventors: Karsten M. Kragh, Bjarne Larsen, Preben Rasmussen, Lene Duedahl-Olesen, Wolfgang Zimmermann
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Patent number: 5608151Abstract: Anti-microbial proteins isolated from sugar beet, wherein the anti-microbial proteins exclude chitinases and glucanases. Said proteins include a pure protein selected from those depicted in SEQ ID Nos 2, 5 and 8, or a functionally equivalent analogue thereof in which one or more amino acids have been added, substituted or removed without substantially reducing the protein's anti-microbial activity, or mixtures of such proteins or analogues. A synergistic anti-fungal effect is observed if at least one of the AX proteins is combined with a WIN protein. The invention also provides recombinant DNA comprising a sequence encoding a protein according to the invention, a vector comprising said DNA and transformed plants comprising said DNA. The invention further provides an anti-microbial composition containing one or more of the said proteins, and a process for combatting fungi or bacteria which comprises exposing them to said proteins or compositions.Type: GrantFiled: April 12, 1995Date of Patent: March 4, 1997Assignee: Sandoz Ltd.Inventors: Kirsten Bojsen, Karsten M. Kragh, J.o slashed.rn D. Mikkelsen, Klaus K. Nielsen, John E. Nielsen
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Patent number: 5607919Abstract: Anti-microbial proteins isolated from sugar beet, wherein the anti-microbial proteins exclude chitinases and glucanases. Said proteins include a pure protein selected from those depicted in SEQ ID Nos 2, 5 and 8, or a functionally equivalent analogue thereof in which one or more amino acids have been added, substituted or removed without substantially reducing the protein's anti-microbial activity, or mixtures of such proteins or analogues. A synergistic anti-fungal effect is observed if at least one of the AX proteins is combined with a WIN protein. The invention also provides recombinant DNA comprising a sequence encoding a protein according to the invention, a vector comprising said DNA and transformed plants comprising said DNA. The invention further provides an anti-microbial composition containing one or more of the said proteins, and a process for combatting fungi or bacteria which comprises exposing them to said proteins or compositions.Type: GrantFiled: October 13, 1995Date of Patent: March 4, 1997Assignee: Sandoz Ltd.Inventors: Kirsten Bojsen, Karsten M. Kragh, J.o slashed.rn D. Mikkelsen, Klaus K. Nielsen, John E. Nielsen