Abstract: The disclosure generally describes computer-implemented methods, software, and systems, including a method for creating and incorporating an optimization solution into a workload placement system. An optimization model is defined for a workload placement system. The optimization model includes information for optimizing workflows and resource usage for in-memory database clusters. Parameters are identified for the optimization model. Using the identified parameters, an optimization solution is created for optimizing the placement of workloads in the workload placement system. The creating uses a multi-start approach including plural initial conditions for creating the optimization solution. The created optimization solution is refined using at least the multi-start approach. The optimization solution is incorporated into workload placement system.