Patents by Inventor Karsten Sternickel

Karsten Sternickel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9655564
    Abstract: The use of machine learning for pattern recognition in magnetocardiography (MCG) that measures magnetic fields emitted by the electrophysiological activity of the heart is disclosed herein. Direct kernel methods are used to separate abnormal MCG heart patterns from normal ones. For unsupervised learning, Direct Kernel based Self-Organizing Maps are introduced. For supervised learning Direct Kernel Partial Least Squares and (Direct) Kernel Ridge Regression are used. These results are then compared with classical Support Vector Machines and Kernel Partial Least Squares. The hyper-parameters for these methods are tuned on a validation subset of the training data before testing. Also investigated is the most effective pre-processing, using local, vertical, horizontal and two-dimensional (global) Mahanalobis scaling, wavelet transforms, and variable selection by filtering.
    Type: Grant
    Filed: October 30, 2015
    Date of Patent: May 23, 2017
    Assignee: Cardio Mag Imaging, Inc.
    Inventors: Karsten Sternickel, Boleslaw Szymanski, Mark Embrechts
  • Publication number: 20160066860
    Abstract: The use of machine learning for pattern recognition in magnetocardiography (MCG) that measures magnetic fields emitted by the electrophysiological activity of the heart is disclosed herein. Direct kernel methods are used to separate abnormal MCG heart patterns from normal ones. For unsupervised learning, Direct Kernel based Self-Organizing Maps are introduced. For supervised learning Direct Kernel Partial Least Squares and (Direct) Kernel Ridge Regression are used. These results are then compared with classical Support Vector Machines and Kernel Partial Least Squares. The hyper-parameters for these methods are tuned on a validation subset of the training data before testing. Also investigated is the most effective pre-processing, using local, vertical, horizontal and two-dimensional (global) Mahanalobis scaling, wavelet transforms, and variable selection by filtering.
    Type: Application
    Filed: October 30, 2015
    Publication date: March 10, 2016
    Inventors: Karsten Sternickel, Boleslaw Szymanski, Mark Embrechts
  • Patent number: 9173614
    Abstract: The use of machine learning for pattern recognition in magnetocardiography (MCG) that measures magnetic fields emitted by the electrophysiological activity of the heart is disclosed herein. Direct kernel methods are used to separate abnormal MCG heart patterns from normal ones. For unsupervised learning, Direct Kernel based Self-Organizing Maps are introduced. For supervised learning Direct Kernel Partial Least Squares and (Direct) Kernel Ridge Regression are used. These results are then compared with classical Support Vector Machines and Kernel Partial Least Squares. The hyper-parameters for these methods are tuned on a validation subset of the training data before testing. Also investigated is the most effective pre-processing, using local, vertical, horizontal and two-dimensional (global) Mahanalobis scaling, wavelet transforms, and variable selection by filtering.
    Type: Grant
    Filed: May 28, 2014
    Date of Patent: November 3, 2015
    Assignee: CardioMag Imaging, Inc.
    Inventors: Karsten Sternickel, Boleslaw Szymanski, Mark Embrechts
  • Publication number: 20140343396
    Abstract: The use of machine learning for pattern recognition in magnetocardiography (MCG) that measures magnetic fields emitted by the electrophysiological activity of the heart is disclosed herein. Direct kernel methods are used to separate abnormal MCG heart patterns from normal ones. For unsupervised learning, Direct Kernel based Self-Organizing Maps are introduced. For supervised learning Direct Kernel Partial Least Squares and (Direct) Kernel Ridge Regression are used. These results are then compared with classical Support Vector Machines and Kernel Partial Least Squares. The hyper-parameters for these methods are tuned on a validation subset of the training data before testing. Also investigated is the most effective pre-processing, using local, vertical, horizontal and two-dimensional (global) Mahanalobis scaling, wavelet transforms, and variable selection by filtering.
    Type: Application
    Filed: May 28, 2014
    Publication date: November 20, 2014
    Applicant: CardioMag Imaging, Inc.
    Inventors: Karsten Sternickel, Boleslaw Szymanski, Mark Embrechts
  • Patent number: 8744557
    Abstract: The use of machine learning for pattern recognition in magnetocardiography (MCG) that measures magnetic fields emitted by the electrophysiological activity of the heart is disclosed herein. Direct kernel methods are used to separate abnormal MCG heart patterns from normal ones. For unsupervised learning, Direct Kernel based Self-Organizing Maps are introduced. For supervised learning Direct Kernel Partial Least Squares and (Direct) Kernel Ridge Regression are used. These results are then compared with classical Support Vector Machines and Kernel Partial Least Squares. The hyper-parameters for these methods are tuned on a validation subset of the training data before testing. Also investigated is the most effective pre-processing, using local, vertical, horizontal and two-dimensional (global) Mahanalobis scaling, wavelet transforms, and variable selection by filtering.
    Type: Grant
    Filed: February 20, 2013
    Date of Patent: June 3, 2014
    Assignee: Cardio Mag Imaging, Inc.
    Inventors: Karsten Sternickel, Boleslaw Szymanski, Mark Embrechts
  • Patent number: 8527435
    Abstract: A novel Levenberg-Marquardt like second-order algorithm for tuning the Parzen window ? in a Radial Basis Function (Gaussian) kernel. Each attribute has its own sigma parameter. The values of the optimized ? are then used as a gauge for variable selection. Kernel Partial Least Squares (K-PLS) model is applied to several benchmark data sets to estimate effectiveness of second-order sigma tuning procedure for an RBF kernel. The variable subset selection method based on these sigma values is then compared with different feature selection procedures such as random forests and sensitivity analysis. The sigma-tuned RBF kernel model outperforms K-PLS and SVM models with a single sigma value. K-PLS models also compare favorably with Least Squares Support Vector Machines (LS-SVM), epsilon-insensitive Support Vector Regression and traditional PLS.
    Type: Grant
    Filed: July 13, 2011
    Date of Patent: September 3, 2013
    Assignee: CardioMag Imaging, Inc.
    Inventors: Long Han, Mark Embrechts, Boleslaw Szymanski, Karsten Sternickel, Alexander Ross
  • Patent number: 8391963
    Abstract: The use of machine learning for pattern recognition in magnetocardiography (MCG) that measures magnetic fields emitted by the electrophysiological activity of the heart is disclosed herein. Direct kernel methods are used to separate abnormal MCG heart patterns from normal ones. For unsupervised learning, Direct Kernel based Self-Organizing Maps are introduced. For supervised learning Direct Kernel Partial Least Squares and (Direct) Kernel Ridge Regression are used. These results are then compared with classical Support Vector Machines and Kernel Partial Least Squares. The hyper-parameters for these methods are tuned on a validation subset of the training data before testing. Also investigated is the most effective pre-processing, using local, vertical, horizontal and two-dimensional (global) Mahanalobis scaling, wavelet transforms, and variable selection by filtering.
    Type: Grant
    Filed: June 18, 2010
    Date of Patent: March 5, 2013
    Assignee: CardioMag Imaging, Inc.
    Inventors: Karsten Sternickel, Boleslaw Szymanski, Mark Embrechts
  • Publication number: 20110047105
    Abstract: The use of machine learning for pattern recognition in magnetocardiography (MCG) that measures magnetic fields emitted by the electrophysiological activity of the heart is disclosed herein. Direct kernel methods are used to separate abnormal MCG heart patterns from normal ones. For unsupervised learning, Direct Kernel based Self-Organizing Maps are introduced. For supervised learning Direct Kernel Partial Least Squares and (Direct) Kernel Ridge Regression are used. These results are then compared with classical Support Vector Machines and Kernel Partial Least Squares. The hyper-parameters for these methods are tuned on a validation subset of the training data before testing. Also investigated is the most effective pre-processing, using local, vertical, horizontal and two-dimensional (global) Mahanalobis scaling, wavelet transforms, and variable selection by filtering.
    Type: Application
    Filed: June 18, 2010
    Publication date: February 24, 2011
    Applicant: CARDIO MAG IMAGING, INC.
    Inventors: Karsten Sternickel, Mark J. Embrechts, Boleslaw Szymanski
  • Patent number: 7742806
    Abstract: The use of machine learning for pattern recognition in magnetocardiography (MCG) that measures magnetic fields emitted by the electrophysiological activity of the heart is disclosed herein. Direct kernel methods are used to separate abnormal MCG heart patterns from normal ones. For unsupervised learning, Direct Kernel based Self-Organizing Maps are introduced. For supervised learning Direct Kernel Partial Least Squares and (Direct) Kernel Ridge Regression are used. These results are then compared with classical Support Vector Machines and Kernel Partial Least Squares. The hyper-parameters for these methods are tuned on a validation subset of the training data before testing. Also investigated is the most effective pre-processing, using local, vertical, horizontal and two-dimensional (global) Mahanalobis scaling, wavelet transforms, and variable selection by filtering. The results, similar for all three methods, were encouraging, exceeding the quality of classification achieved by the trained experts.
    Type: Grant
    Filed: July 1, 2004
    Date of Patent: June 22, 2010
    Assignee: CardioMag Imaging, Inc.
    Inventors: Karsten Sternickel, Boleslaw Szymanski, Mark Embrechts
  • Publication number: 20070167846
    Abstract: The use of machine learning for pattern recognition in magnetocardiography (MCG) that measures magnetic fields emitted by the electrophysiological activity of the heart is disclosed herein. Direct kernel methods are used to separate abnormal MCG heart patterns from normal ones. For unsupervised learning, Direct Kernel based Self-Organizing Maps are introduced. For supervised learning Direct Kernel Partial Least Squares and (Direct) Kernel Ridge Regression are used. These results are then compared with classical Support Vector Machines and Kernel Partial Least Squares. The hyper-parameters for these methods are tuned on a validation subset of the training data before testing. Also investigated is the most effective pre-processing, using local, vertical, horizontal and two-dimensional (global) Mahanalobis scaling, wavelet transforms, and variable selection by filtering. The results, similar for all three methods, were encouraging, exceeding the quality of classification achieved by the trained experts.
    Type: Application
    Filed: July 1, 2004
    Publication date: July 19, 2007
    Applicant: CardioMag Imaging, Inc.
    Inventors: Karsten Sternickel, Boleslaw Szymanski, Mark Embrechts