Abstract: A command line interface in a network device provides for specifying Virtual Local Area Network (VLAN) tag manipulations using range mappings to avoid error-prone repetitive configuration. A flexible VLAN tag range mapping is described, where the original and transformed ranges can be specified for both inner and outer positions, as long as the number of tags on either side of the transformation is the same.

Abstract: Each switch unit in a networking system shares its local state information among other switch units in the networking system, collectively referred to as the shared forwarding state. Each switch unit creates a respective set of output queues that correspond to ports on other switch unites based on the shared forwarding state. A received packet on an ingress switch unit operating in accordance with a first routing protocol instance can be enqueued on an output queue in the ingress switch; the packet is subsequently processed by the egress switch unit, operating in accordance with a second routing protocol instance that corresponds to the output queue.

Abstract: Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus.

Abstract: Anti-CCHFV antibodies with neutralizing potency and protective efficacy against CCHFV are provided, as well as methods for their identification, isolation, generation, and methods for their preparation and use are provided.

Abstract: The present invention is related to the development of therapeutics and prophylactics for the treatment and/or prevention of filovirus infection in humans and other mammals. A new class of small molecules is disclosed that inhibits the interaction of naturally processed (i.e., proteolytically cleaved) filovirus glycoprotein (GPCL) with its host receptor Niemann-Pick C1 (NPC1) protein and thus block infection of host cells by filoviruses. Also disclosed are methods of using the small molecule inhibitors in the treatment/prevention of filovirus infection.

Abstract: Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus.

Abstract: Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially, similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus.

Abstract: Each switch unit in a networking system shares its local state information among other switch units in the networking system, collectively referred to as the shared forwarding state. Each switch unit creates a respective set of output queues that correspond to ports on other switch unites based on the shared forwarding state. A received packet on an ingress switch unit operating in accordance with a first routing protocol instance can be enqueued on an output queue in the ingress switch; the packet is subsequently processed by the egress switch unit, operating in accordance with a second routing protocol instance that corresponds to the output queue.

Abstract: Methods and systems for modifying network traffic data. The method of modifying network traffic may include receiving a network traffic data unit that includes an identifier, at a proxy port; based on the identifier, performing a proxy port action set to obtain a modified network traffic data unit; and transmitting the modified network traffic data unit towards an egress port.

Abstract: Each switch unit in a networking system shares its local state information among other switch units in the networking system, collectively referred to as the shared forwarding state. Each switch unit creates a respective set of output queues that correspond to ports on other switch unites based on the shared forwarding state. A received packet on an ingress switch unit operating in accordance with a first routing protocol instance can be enqueued on an output queue in the ingress switch; the packet is subsequently processed by the egress switch unit, operating in accordance with a second routing protocol instance that corresponds to the output queue.

Abstract: Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus.

Abstract: Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus.

Abstract: Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially, similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus.

Abstract: Anti-CCHFV antibodies with neutralizing potency and protective efficacy against CCHFV are provided, as well as methods for their identification, isolation, generation, and methods for their preparation and use are provided.

Abstract: Disclosed are bispecific antibodies and bispecific fusion constructs that bind to Niemann-Pick C1 (NPC1) receptor for treating or preventing filovirus infections, pharmaceutical compositions comprising the bispecific antibodies, and therapeutic methods using the bispecific antibodies.

Abstract: The present invention addresses a need for antibodies useful for filovirus infections.

Abstract: Each switch unit in a networking system shares its local state information among other switch units in the networking system, collectively referred to as the shared forwarding state. Each switch unit creates a respective set of output queues that correspond to ports on other switch unites based on the shared forwarding state. A received packet on an ingress switch unit operating in accordance with a first routing protocol instance can be enqueued on an output queue in the ingress switch; the packet is subsequently processed by the egress switch unit, operating in accordance with a second routing protocol instance that corresponds to the output queue.

Abstract: Methods and systems for modifying network traffic data. The method of modifying network traffic data may include receiving a network traffic data unit by a switching engine; performing an analysis on the network traffic data unit to obtain network tunnel information; generating encryption information based on the network tunnel information; and securing the network traffic data unit, by an encryption engine, based on the encryption information.

Abstract: Methods and systems for controlling a denitrification reaction in a biological nitrogen removal reactor including denitrifying bacteria to favor denitratation of nitrate to nitrite and limit denitritation of nitrite to nitrogen gas are disclosed. pH, dissolved oxygen levels, solids retention time, and chemical oxygen demand to nitrogen ratio are controlled to favor this reaction. Wastewater or contaminated groundwater including concentrations of ammonium and nitrate are continuously fed to the biological nitrogen removal reactor along with a source of carbon and electrons as an influent, which is treated to form a nitrite effluent. The nitrite effluent may then be fed to an anammox reactor including anammox bacteria for production of nitrogen gas. The system may be operated under substantially anoxic conditions, which provides significant cost savings without sacrificing efficiency or productivity compared to traditional wastewater treatment systems and processes.

Abstract: The present invention addresses a need for antibodies useful for filovirus infections.