Patents by Inventor Kasper Huus

Kasper Huus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical formulations comprising an insulin derivative
    Patent number: 9034818
    Abstract: The invention concerns a soluble pharmaceutical formulation comprising an insulin derivative wherein the formulation further comprises more than 4 zinc atoms per 6 molecules of the insulin derivative, and a citric acid monohydrate and/or a histidine compound used in an amount sufficient to increase the tendency of the insulin derivative to self-associate into dodecamers. The invention further comprises a process for preparing the soluble pharmaceutical formulation.
    Type: Grant
    Filed: June 12, 2008
    Date of Patent: May 19, 2015
    Assignee: Novo Nordisk A/S
    Inventors: Christian Poulsen, Kasper Huus, Frantisek Hubalek, Dorte Bjerre Steensgaard, Svend Havelund
  • GLP-1 COMPOSITIONS
    Publication number: 20140045754
    Abstract: The present invention relates to pharmaceutical compositions comprising a GLP-1 compound, a divalent metal and a polycationic compound. The invention is characterised in that the GLP-1:divalent metal molar ratio is 1:>2. The compositions of the invention are particularly useful in the treatment of diabetes.
    Type: Application
    Filed: January 19, 2012
    Publication date: February 13, 2014
    Inventors: Joern Drustrup, Kasper Huus, Per Balschmidt
  • GLP-1 PARTICLES AND COMPOSITIONS
    Publication number: 20140004198
    Abstract: The present invention relates to compositions and particles comprising a GLP-1 compound, a divalent metal and a polycationic compound. The invention is characterised that the particle comprises a core and a surrounding layer, the core comprising the GLP-1 compound and the divalent metal, and the surrounding layer comprising the polycationic compound. The invention is particularly useful for the treatment of metabolic diseases, including diabetes.
    Type: Application
    Filed: January 19, 2012
    Publication date: January 2, 2014
    Applicant: Novo Nordisk A/S
    Inventors: Per Balschmidt, Joern Drustrup, Kasper Huus
  • Pharmaceutical Formulations Comprising an Insulin Derivative
    Publication number: 20100167990
    Abstract: The invention concerns a soluble pharmaceutical formulation comprising an insulin derivative wherein the formulation further comprises more than 4 zinc atoms per 6 molecules of the insulin derivative, and a citric acid monohydrate and/or a histidine compound used in an amount sufficient to increase the tendency of the insulin derivative to self-associate into dodecamers. The invention further comprises a process for preparing the soluble pharmaceutical formulation.
    Type: Application
    Filed: June 12, 2008
    Publication date: July 1, 2010
    Applicant: NOVO NORDISK A/S
    Inventors: Christian Poulsen, Kasper Huus, Frantisek Hubalek, Dorte Bjerre Steensgaard, Sven Havelund
  • Polyamino acid-based particle insulin preparation
    Publication number: 20040005999
    Abstract: This invention relates to sustained release preparations of insulin comprising polyamino acid particles, insulin and one or more preservative agents, and a method of preparing such preparations.
    Type: Application
    Filed: March 7, 2003
    Publication date: January 8, 2004
    Inventors: Kasper Huus Andreasen, Per Balschmidt, Lone Kimer
  • Polyamino acid-based particle insulin formulation
    Publication number: 20030211976
    Abstract: This invention relates to dual-release formulations of insulin comprising polyamino acid particles and insulin, and a method of preparing such formulations
    Type: Application
    Filed: March 7, 2003
    Publication date: November 13, 2003
    Inventors: Kasper Huus Andreasen, Lone Kimer