Abstract: The present invention relates to a microfluidic device (10) suitable for accommodating an aqueous liquid, the device having essentially a planar shape, which device comprises at least one conduit (11) fluidically connecting at least two structures selected from compartments, reservoirs (14) and/or ports (15, 62). The conduit comprises at least one bend (12) describing an angle of between ?85° and ?275° around an axis orthogonal to the planar shape. The planar shape is arranged in an angle of between +45° and ?45° relative to the direction of the force of gravity (G), or a centrifugal force (Fc) applied to the microfluidic device.

Abstract: A composition is provided, including eukaryotic microalgae or an extract thereof for treatment of a viral disease such as coronavirus, and for use as an inhibitor of the binding of Spike protein receptor binding domain (RBD) to Angiotensin-Converting Enzyme 2 (ACE2). A compound derivable from the eukaryotic microalgae is also provided for treatment of a viral disease. A composition is also provided, including prokaryotic microalgae or an extract thereof for treatment of a viral disease.

Abstract: Methods of forming, dissolving, and functionalizing an extracellular matrix gel on demand based on cross-linking, modification, and dissolution of hydrogels using transpeptidase (e.g. sortase) are disclosed. Also provided are hydrogels comprising one or more macromers crosslinked to a mixture of peptides, wherein all or a portion of the peptides in the mixture comprise a recognition motif cleavable by a transpeptidase (e.g., sortase).