Patents by Inventor Kastuhide Kamei

Kastuhide Kamei has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process of production of 4-substituted-3-halogeno-1,4-benzoxazepine derivative and salts thereof
    Patent number: 6114522
    Abstract: A process for producing 4-substituted-3-halogeno-1,4-benzoxazepin derivative or the salt thereof comprising: deprotonizing a benzoxazepine derivative having the formula (II): ##STR1## with a base; and then, reacting the deprotonized product with a phosphate halide to produce an intermediate having the formula (IV): ##STR2## and then, reacting the resultant intermediate (IV) with a reagent selected from (i) a complex of a phosphine with chlorine or bromine, (ii) a phosphine and a chlorine gas or liquid bromine, (iii) a phosphine and tetrachloromethane or tetrabromomethane, or (iv) a halogenated phosphite ester to produce a 4-substituted-3-halogeno-1,4-benzoxazepine derivative having the formula (I) ##STR3## wherein X indicates a chlorine atom or a bromine atom, or its salt.
    Type: Grant
    Filed: November 24, 1999
    Date of Patent: September 5, 2000
    Assignee: Suntory Limited
    Inventors: Kastuhide Kamei, Noriko Maeda, Toshio Tatsuoka