Patents by Inventor Katalin Horváth
Katalin Horváth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20080269202Abstract: Disclosed are novel 2,3-benzodiazepine derivatives and methods of making the same.Type: ApplicationFiled: April 2, 2008Publication date: October 30, 2008Applicant: Teva Pharmaceutical Industries Ltd.Inventors: Emese Csuzdi, Sandor Solyom, Pal Berzsenyi, Ferenc Andrasi, Istvan Sziraki, Katalin Horvath, Zoltan Nagy
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Patent number: 6602865Abstract: Pyridazino(4,5-b)(1,5)oxazepinone, thiazepinone and diazepinone compounds of formula(I) and their tautomers and the acid-addition salts of all these compounds show memory-enhancing and neuroprotective properties.Type: GrantFiled: November 15, 1999Date of Patent: August 5, 2003Assignee: IVAX Drug Research Institute, Ltd.Inventors: Ferenc Andrasi, Agnes Angyal nee Pataky, Pal Berzsenyi, Sandor Boros, Laszlo Harsing, Katalin Horvath, Peter Matyus, Imre Moravcsik, Agnes Papp nee Behr, Antal Simay, Erzsebet Szabo nee Bagdy, Katalin Szabo nee Pusztai, Istvan Tarnawa, Ildiko Varga
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Patent number: 6600036Abstract: Compounds of formula I are described, their production and use in pharmaceutical agents.Type: GrantFiled: November 27, 2001Date of Patent: July 29, 2003Assignee: Schering AktiengesellschaftInventors: Ernese Csuzdi, Tamas Hamori, Gizella Abraham, Sandor Solyom, Istvan Tarnawa, Pal Berzsenyi, Ferenc Andrasi, Istvan Ling, Antal Simay, Melinda Gal, Katalin Horvath, Eszter Szentkuti, Marta Szollosy, Istvan Pallagi
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Patent number: 6482819Abstract: 2,3-Benzodiazepines of formula (I), their stereoisomers and acid addition salts, wherein the variables have the meaning given in the specification, and pharmaceutical compositions containing them which are suitable for treating conditions associated with muscle spasms, epilepsy as well as acute and chronic forms of neurodegenerative diseases are disclosed.Type: GrantFiled: April 10, 2000Date of Patent: November 19, 2002Assignee: Gyogyszerkutato Intezet Kft.Inventors: Gizella Ábrahám, Emese Csuzdi, Sándor Sólyom, Pál Berzsenyi, István Tarnawa, Ferenc Andrási, István Ling, Tamás Hámori, Katalin Horváth, Imre Moravcsik, István Pallagi, Antal Simay
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Publication number: 20020052364Abstract: Compounds of formula I are described, their production and use in pharmaceutical agents.Type: ApplicationFiled: November 27, 2001Publication date: May 2, 2002Inventors: Ernese Csuzdi, Tamas Hamori, Gizella Abraham, Sandor Solyom, Istvan Tarnawa, Pal Berzsenyl, Ferenc Andrasi, lstvan Ling, Antal Simay, Melinda Gal, Katalin Horvath, Eszter Szentkuti, Marta Szollosy, Istvan Pallagi
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Patent number: 6323197Abstract: The invention concerns compounds of formula (I), in which R1, R2, R3 and R4 mean hydrogen or different substituents; X means hydrogen or halogen; Y means C1-6 alkoxy or X and Y together mean —O—(CH2)n—O—; n means 1, 2 or 3; and A together with nitrogen forms a saturated or unsaturated five-member heterocycle which can contain between 1 and 3 nitrogen atoms and/or an oxygen atom and/or one or two carbonyl groups. Owing to their non-competitive inhibiting of the AMPA receptors, these compounds can be used as medicaments for treating diseases of the central nervous system.Type: GrantFiled: November 5, 1998Date of Patent: November 27, 2001Assignee: Schering AktiengesellschaftInventors: Ernese Csuzdi, Tamas Hámori, Gizella Ábrahám, Sändor Sólyom, István Tarnawa, Pál Berzsenyi, Ferenc Andrási, István Ling, Antal Simay, Melinda Gál, Katalin Horváth, Eszter Szentkuti, Márta Szöllosy, István Pallagi
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Patent number: 6248907Abstract: The invention relates to R-2-[3-([1,4]benzodioxan-2-ylmethylamino)-1-propyl]-3(2H)-pyridazinone of formula (1), and to S-2-[3-([1,4]benzodioxan-2-ylmethylamino)-1-propyl]-3(2H)-pyridazinone of formula (2), and to acid-addition salts thereof as well as pharmaceutical compositions containing these compounds. Furthermore, the invention relates to a process for the preparation of the above compounds. The new starting compounds of formulae (4) and (5) are also involved in the scope of the invention. The compounds according to the invention possess &agr;1- and &agr;2-adrenoceptor antagonistic effects and urogenital selectivity. Thus, they are useful for the treatment of the benign prostate hyperplasia.Type: GrantFiled: August 28, 2000Date of Patent: June 19, 2001Assignee: Gyogyszerkutato Intezet Kft.Inventors: Péter Mátyus, László Hársing, Marianne Tapfer née Karim, Judit Kosáry, Ágnes Papp née Behr, Antal Simay, Yemane Tilahun, Éva Tomori née Joszt, Edit Horváth, Katalin Horváth, Ildikó Varga, Erzsébet Zára née Kaczián, Margit Bidló née Iglóy, Alice Druga, György Rabloczky, Márta Varga, Egon Kárpáti, Endre Kasztreiner, István Király, Ildikó Máthé née Gyóry, György Máthé, László Sebestyén, Nándor Makk
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Patent number: 6200970Abstract: A compound of formula I in which X means hydrogen or halogen, Y means —NR3— or —N═, R1 and R2 are the same or different and mean hydrogen, C1-C6 alkyl, nitro, halogen, the group —NR8R9, —O—C1-4 alkyl, —CF3, OH or C1-6 alkanoyloxy, R3 means hydrogen, the group —CO—R10, C1-6 alkyl or C3-7 cycloalkyl, R4 means optionally substituted C1-C6 alkyl, R5 means hydrogen or R4 and R5 together mean oxygen, R6 means C1-4 alkyl, R8 and R9 are the same or different and mean hydrogen, C1-C6 alkyl or —CO—C1-6 alkyl, R10 means hydrogen, optionally substituted C1-C6 alkyl, optionally substituted C6-10 aryl, the group —NR11R12, —O—C1-6 alkyl, C3-7 cycloalkyl, C2-6 alkenyl or —O—C3-7 cycloalkyl, R11 and R12 are the same or different and mean hydrogen, optionally substituted C1-C6 alkyl or optionally substituted C6-10 aryl and —C...C...Type: GrantFiled: November 5, 1998Date of Patent: March 13, 2001Assignee: Schering AktiengesellschaftInventors: István Ling, Gizella Ábrahám, Sándor Sólyom, Tamás Hámori, István Tarnawa, Pál Berzsenyi, Ferenc Andrási, Emese Csuzdi, Márta Szöllósy, Antal Simay, István Lagi, Katalin Horváth
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Patent number: 6194411Abstract: The invention relates to R-2-[3-([1,4]benzodioxan-2-ylmethylamino)-1-propyl]-3(2H)-pyridazionone of formula (1) and to S-2-[3-([1,4]benzodioxan-2-ylmethylamino)-1-propyl]-3(2H)-pyridazionone of formula (2) and to acid-addition salts thereof as well as pharmaceutical compositions containing these compounds. Furthermore, the invention relates to a process for the preparation of the above compounds. The new starting compounds of formula (4) and (5) are also involved in the scope of the invention. The compounds according to the invention possess &agr;1- and &agr;2-adrenoceptor antagonistic effects and urogenital selectivity. Thus, they are useful for the treatment of the benign prostate hyperplasia.Type: GrantFiled: July 20, 1998Date of Patent: February 27, 2001Assignee: Gyogyszerkutato Intezet Kft.Inventors: Péter Mátyus, László Hársing, Mariann née Tapfer Karim, Judit Kosáry, Ágnes née Behr Papp, Antal Simay, Yemane Tilahun, Éva née Joszt Tomori, Edit Horváth, Katalin Horváth, Ildikó Varga, Erzsébet née Kaczián Zára, Margit née Iglóy Bidló, Alice Druga, György Rabloczky, Márta Varga, Egon Kárpáti, Endre Kasztreiner, István Király, Ildikó née Gyóry Máthé, György Máthé, László Sebestyén, Nándor Makk
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Patent number: 6075018Abstract: The invention relates to new 1-[2-(substituted vinyl)]-3,4-dihydro-5H-2,3-benzodiazepine derivatives, a process for the preparation thereof and pharmaceutical compositions comprising them. The new 1-[2-(substituted vinyl)]-3,4-dihidro-5H-2,3-benzodiazepine derivatives according to the invention correspond to the general formula (I), ##STR1## wherein the variables are hereinbelow defined: The new compounds according to the invention affect the central nervous system and can be used to advantage in the therapy.Type: GrantFiled: February 9, 1996Date of Patent: June 13, 2000Assignee: Egis Gyogyszergyar Rt.Inventors: Pal Vago, Jozsef Reiter, Istvan Gyertyan, Gabor Gigler, Ferenc Andrasi, Anna Bakonyi, Pal Berzsenyi, Peter Botka, deceased, Erszebet Birkas, Tamas Hamori, Edit Horvath, Katalin Horvath, Jeno Korosi, deceased, Gyorgyne Mate, Imre Moravcsik, Gyorgy Somogyi, Eszter Szentkuti, Gabor Zolyomi
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Patent number: 5942506Abstract: This invention relates to new 1-?2-(substituted vinyl)!-5H-2,3-benzodiazepine derivatives, a process for the preparation thereof, pharmaceutical compositions comprising the same, to the use of the said benzodiazepine derivatives for the treatment of diseases and for the preparation of pharmaceutical compositions suitable for the treatment of diseases. The compounds according to the invention correspond to the general formula (I), ##STR1## wherein the variables are herein below defined, and the compounds possess central nervous activities.Type: GrantFiled: February 9, 1996Date of Patent: August 24, 1999Assignee: GIS Gyogyszergyar Rt.Inventors: Pal Vago, Jozsef Reiter, Istvan Gyertyan, Istvan Gacsalyi, Andras Bilkei-Gorzo, Andras Egyed, Ferenc Andrasi, Anna Bakonyi, Pal Berzsenyi, Hilda Botka, Tamas Hamori, Cecilia Salamon Haskane, Edit Horvath, Katalin Horvath, Peter Korosi, Gyorgyne Mate, Imre Moravcsik, Eszter Szentkuti, Gabor Zolyomi, Gabor Blasko, Klara Daroczi Kazone, Gyula Simig, Karoly Tihanyi, Judit Bajnogel
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Patent number: 5807851Abstract: Derivatives of 2,3-benzodiazepine are substituted by one or two halogen atom(s) and have the general formula ##STR1## These derivatives are non-competitive AMPA antagonists and are used in pharmaceutical compositions.Type: GrantFiled: April 4, 1997Date of Patent: September 15, 1998Assignee: Egis Gyogyszergyar Rt.Inventors: Istvan Ling, Gizella Abraham, Pal Berzsenyi, Istvan Tarnawa, Sandor Solyom, Ferenc Andrasi, Tamas Hamori, Emese Csuzdi, Katalin Horvath, Melinda Gal, Imre Moravcsik, Marta Szollosy
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Patent number: 5122607Abstract: New intermediate compounds are disclosed of the formula I, ##STR1## wherein R.sub.1 and R.sub.2 are independently alkyl having 1 to 4 carbon atoms,or acid-addition salts thereof of formula Ib, ##STR2## wherein X represents an acid residue, and a process for the preparation of the intermediate compounds.Type: GrantFiled: June 21, 1990Date of Patent: June 16, 1992Assignee: Richter Gedeon Vegyesczeti Gyar RT.Inventors: Janos Kreidl, Csaba Szantay, Lajos Szaho, Maria Farkas nee Kirjak, Gyorgy Kalaus, Katalin Nogradi, Andras Nemes, Judit Meszaros nee Brill, Zsuzsanna Aracs nee Tischler, Bela Stefko, Janos Sapi, Ida Deutsch nee Juhasz, Istvan Hegedus, Bela Benke, Kalman Graf, Kalmam Gaf, Katalin Horvath nee Berki