Patents by Inventor Katalin Pallagi
Katalin Pallagi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20120108607Abstract: The present invention relates to the enantiomers of 5,7-dichloro-3-{4-[4-(4-chlorophenyl)-piperazin-1-yl]butyl}-3-ethyl-1,3-dihydro-2H-indol-2-one of the Formula (II) pharmaceutically acceptable salts thereof, process for the preparation thereof, medicinal products containing said enantiomers and the use thereof and their pharmaceutically acceptable salts in the treatment of the disorders of the central nervous system.Type: ApplicationFiled: February 5, 2010Publication date: May 3, 2012Inventors: Balázs Volk, József Barkóczy, István Gacsalyi, Elemér Fogassy, József Schindler, Gábor Gigler, Hajnalka Kompagne, Iidikó Nagyné Gyoenos, Katalin Pallagi, Márta Porcs-Makkay, Gábor Szénási, Tibor Mezel, Gyula Lukács, Gyoergy Lévay, András Egyed, László Gábor Hársing
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Patent number: 7910591Abstract: The present invention is concerned with new indol-2-one derivatives of Formula (I), which have favorable activity profile for the prophylaxis and treatment of disorders in the central nervous or in the cadiovascular system.Type: GrantFiled: May 11, 2005Date of Patent: March 22, 2011Assignee: EGIS Gyogyszergyar NYRT.Inventors: Balázs Volk, József Barkóczy, Gyula Simig, Tibor Mezei, Rita Kapillerné Dezsöfi, István Gacsályi, Katalin Pallagi, Gábor Gigler, György Lévay, Krisztina Móricz, Csilla Leveleki, Nóra Sziray, Gábor Szenasi, András Egyed, László Gábor Hársing
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Patent number: 7786129Abstract: The present invention is concerned with new 3,3-disubstituted indol-2-one derivatives of the general Formula (I), wherein R1 stands for hydrogen, halogen, alkyl having 1-7 carbon atom(s) or sulfonamido; R2 represents hydrogen or halogen; R3 denotes hydrogen, alkyl having 1-7 carbon atom(s) optionally carrying an aryl substituent or aryl optionally carrying one or two halogen substituent(s); R4 stands for alkyl having 1-7 carbon atom(s); R5 represents a group of the general Formula (II a) or (II b), wherein Q and W each represents nitrogen or CH; R6, R7 and R8 each stands for hydrogen, halogen, trifluoromethyl, alkyl or alkoxy having 1-7 carbon atom(s), or R6 and R7 together represent ethylenedioxy; m is 0, 1, or 2; a is a single, double or triple bond; n is 0, 1 or 2; and pharmaceutically acceptable acid addition salts thereof which are useful in the treatment or prophylaxis of diseases of the central nervous system, the gastrointestinal system and the cardiovascular system.Type: GrantFiled: May 11, 2005Date of Patent: August 31, 2010Assignee: Egis Gyogyszergyar NyrtInventors: Balázs Volk, József Barkóczy, Gyula Simig, Tibor Mezei, Rita Kapillerné Dezsöfi, Endréné Flórian, István Gacsályi, Katalin Pallagi, Gábor Gigler, György Lévay, Krisztina Móricz, Csilla Leveleki, Nóra Sziray, Gábor Szénási, András Egyed, László Gábor Hársing
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Publication number: 20090306144Abstract: New 3,3-disubstituted indol-2-one derivatives of the general formula (I) Compounds according to the invention are useful for the prophylaxis or treatment of the disorders of the central nervous system.Type: ApplicationFiled: July 28, 2009Publication date: December 10, 2009Inventors: Balazs VOLK, József Barkóczy, Gyula Simig, Tibor Mezei, Rita Kapillerné Dezsòfi, István Gacsályi, Katalin Pallagi, Gábor Gigler, György Lévay, Krisztina Móricz, Csilla Leveleki, Nóra Sziray, Gabor Szénási, András Egyed, Lászió Gábor Hársing
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Publication number: 20090281137Abstract: The present invention is related to new 3,3-disubstituted indol-2-one derivatives of the general Formula (I) The new compounds are useful for the treatment or prophylaxis of the central nervous system, the gastrointestinal system or the cardiovascular system.Type: ApplicationFiled: July 9, 2009Publication date: November 12, 2009Inventors: Balázs Volk, József Barkóczy, Gyula Simig, Tibor Mezei, Rita Kapillerné Dezsófi, István Gacsályi, Katalin Pallagi, Gábor Gigler, Gyôrgy Lévay, Krisztina Móricz, Csilla Leveleki, Nóra Sziray, Gábor Szénási, András Egyed, László Gábor Hársing
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Publication number: 20080161323Abstract: The present invention is concerned with new indol-2-one derivatives of Formula (I), which have favourable activity profile for the prophylaxis and treatment of disorders in the central nervous or in the cadiovascular system.Type: ApplicationFiled: May 11, 2005Publication date: July 3, 2008Applicant: EGIS GYOGYSZERGYAR RT.Inventors: Balazs Volk, Jozsef Barkoczy, Gyula Simig, Tibor Mezei, Rita Kapillerne Dezsofi, Istvan Gacsalyi, Katalin Pallagi, Gabor Gigler, Gyorgy Levay, Krisztina Moricz, Csilla Leveleki, Nora Sziray, Gabor Szenasi, Andras Egyed, Laszlo Gabor Harsing
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Publication number: 20070265300Abstract: The present invention is concerned with new 3,3-disubstituted indol-2-one derivatives of the general Formula (I). Compounds according to the invention are useful for the prophylaxis or treatment of the disorders of the central nervous system.Type: ApplicationFiled: May 10, 2005Publication date: November 15, 2007Applicant: Egis gyogyszergyar rt.Inventors: Balazs Volk, Jozsef Barkoczy, Gyula Simig, Tibor Mezei, Rita Kapillerne Dezsofi, Istvan Gacsalyi, Katalin Pallagi, Gabor Gigler, Gyorgy Levay, Krisztina Moricz, Csilla Leveleki, Nora Sziray, Gabor Szenasi, Andras Egyed, Laszlo Harsing
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Publication number: 20070232662Abstract: The present invention is related to new 3,3-disubstituted indol-2-one derivatives of the general Formula (I). The new compounds are useful for the treatment or prophylaxis of the central nervous system, the gastrointestinal system or the cardiovascular system.Type: ApplicationFiled: May 11, 2005Publication date: October 4, 2007Applicant: Egis Gyogyszergyar RT.Inventors: Balazs Volk, Jozsef Barkoczy, Gyula Simig, Tibor Mezei, Rita Kapillerne Dezsofi, Istvan Gacsalyi, Katalin Pallagi, Gabor Gigler, Gyorgy Levay, Krisztina Moricz, Csilla Leveleki, Nora Sziray, Gabor Szenasi, Andras Egyed, Laszlo Harsing
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Publication number: 20070232619Abstract: The present invention is concerned with new 3,3-disubstituted indol-2-one derivatives of the general Formula (I), wherein R1 stands for hydrogen, halogen, alkyl having 1-7 carbon atom(s) or sulfonamido; R2 represents hydrogen or halogen; R3 denotes hydrogen, alkyl having 1-7 carbon atom(s) optionally carrying an aryl substituent or aryl optionally carrying one or two halogen substituent(s); R4 stands for alkyl having 1-7 carbon atom(s); R5 represents a group of the general Formula (II a) or (II b), wherein Q and W each represents nitrogen or CH; R6, R7 and R8 each stands for hydrogen, halogen, trifluoromethyl, alkyl or alkoxy having 1-7 carbon atom(s), or R6 and R7 together represent ethylenedioxy; m is 0, 1, or 2; a is a single, double or triple bond; n is 0, 1 or 2; and pharmaceutically acceptable acid addition salts thereof which are useful in the treatment or prophylaxis of diseases of the central nervous system, the gastrointestinal system and the cardiovascular system.Type: ApplicationFiled: May 11, 2005Publication date: October 4, 2007Applicant: EGIS GYOGYSZERGYAR RT.Inventors: Balazs Volk, Jozsef Barkoczy, Gyula Simig, Tibor Mezei, Rita Dezsofi, Endrene Florian, Istvan Gacsalyi, Katalin Pallagi, Gabor Gigler, Gyorgy Levay, Krisztina Moricz, Csilla Leveleki, Nora Sziray, Gabor Szenasl, Andras Egyed, Laszlo Harsing
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Publication number: 20070219209Abstract: The present invention is concerned with new indol-2-one derivatives of the general Formula (I). The new compounds are useful for the treatment or prevention of the disorders of the central nervous system or the cardiovascular system.Type: ApplicationFiled: May 10, 2005Publication date: September 20, 2007Applicant: GYÓGYSZERGYÁR RT.Inventors: Balazs Volk, Jozsef Barkoczy, Gyula Simig, Tibor Mezei, Rita Kapillerne Dezsofi, Istvan Gacsalyi, Katalin Pallagi, Gabor Gigler, Gyorgy Levay, Krisztina Moricz, Csilla Leveleki, Nora Sziray, Gabor Szenasi, Andras Egyed, Laszlo Harsing
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Patent number: 7098210Abstract: The invention refers to novel 2H-pyridazine-3-one derivatives of the formula I, pharmaceutical compositions containing the same and a process for the preparation of the active ingredient. The novel compounds possess neuroleptic effect and can be used, primarily, for the treatment of schizophrenia. In formula I, R stands for a hydrogen atom or a C1-4, alkyl group, X and Y represent, independently, a hydrogen atom, a halogen atom or a group of the formula II, with the proviso that one of X and Y means always a group of the formula II, and then the other one stands for a hydrogen atom or a halogen atom, wherein in formula II n has a value of 1 or 2.Type: GrantFiled: July 24, 2002Date of Patent: August 29, 2006Assignee: Egis Gyógyszergyár Rt.Inventors: József Barkóczy, Péter Kótay Nagy, Gyula Simig, György Lévay, István Gacsályi, András Egyed, Judit Ráczné Bajnógel, Katalin Pallagi, Éva Schmidt, Gábor Szénási, Anikó Miklósné Kovács, János Wellmann
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Publication number: 20040186170Abstract: The present invention is a piperazinylalkylbenzofuran derivative of the formula 1Type: ApplicationFiled: December 15, 2003Publication date: September 23, 2004Applicant: EGIS GYOGYSZERGYARInventors: Katalin Ivanicsne Megyeri, Aniko Miklosne Kovacs, Ildiko Nagyne Gyonos, Bela Agai, Jozsef Reiter, Gyula Simig, Endre Rivo, Zoltan Tamas Nagy, Levente Ondi, Szabolcs Keriesz, Gabor Szenasi, Eva Schmidt, Katalin Pallagi, Istvan Gacsalyi, Istvan Gyeriyan, Tamas Szabados, Gyorgy Levay, Andras Egyed
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Publication number: 20040171619Abstract: The invention refers to novel 2H-pyridazine-3-one derivatives of the formula I, pharmaceutical compositions containing the same and a process for the preparation of the active ingredient. The novel compounds possess neuroleptic effect and can be used, primarily, for the treatment of schizophrenia. In formula I, R stands for a hydrogen atom or a C1-4, alkyl group, X and Y represent, independently, a hydrogen atom, a halogen atom or a group of the formula II, with the proviso that one of X and Y means always a group of the formula II, and then the other one stands for a hydrogen atom or a halogen atom, wherein in formula II n has a value of 1 or 2.Type: ApplicationFiled: April 23, 2004Publication date: September 2, 2004Inventors: Jozsef Barkoczy, Peter Kotay Nagy, Gyula Simig, Gyorgy Levay, Istvan Gacsalyi, Andras Egyed, Judit Raczne Bajnogel, Katalin Pallagi, Eva Schmidt, Gabor Szenasi, Aniko Miklosne Kovacs, Janos Wellmann
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Patent number: 6191152Abstract: The invention refers to novel 2-(1,2,4-triazole-1-yl)-1,3,4-thiadiazole derivatives of formula (I) having an influence on the heart and the central nervous system, furthermore pharmaceutical compositions containing the above derivatives, and a process for the preparations of the novel compounds.Type: GrantFiled: September 20, 1999Date of Patent: February 20, 2001Assignee: EGIS Gyógyszergyar Rt.Inventors: József Reiter, József Barkóczy, Gábor Berecz, Gyula Simig, András Egyed, Katalin Ivanicsné Megyeri, Sándor Drabant, Szabolcs Kertész, Anikó Miklósné Kovács, Ildikó Nagyné Gyönös, Mária Szécseyné Hegedüs, Gábor Szénási, János Wellmann, Katalin Pallagi, Éva Schmidt, Károly Tihanyi, Péter Trinka, Margit Csörgö
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Patent number: 5889018Abstract: The invention relates to anxiolytic pharmaceutical compositions comprising as active ingredient 1-sytrylisoquinoline derivatives of general formula (I), whereinn is 1, 2, 3 or 4;R may be the same or different and represent(s) hydrogen, lower alkyl, lower alkoxy or hydroxy, or two substituents R attached to adjacent carbon atoms may form together an alkylenedioxy group;R.sup.1 represents hydrogen or lower alkyl, andAr stands for an optionally substituted aryl or heteroaryl,Some of the compounds of general formula (I) is known, but the majority thereof has not so far described in the literature.The invention also encompasses the preparation of the new compounds of general formula (I), which comprises reacting a compound of general formula (II) with an aldehyde or general formula (III) in the presence of a condensing agent or an acidic catalyst.Type: GrantFiled: May 3, 1995Date of Patent: March 30, 1999Assignee: Egis Gyogyszergyar RT.Inventors: Gyula Balogh, deceased, Imre Doman, Gabor Blasko, Gyula Simig, Erzsebet Kovacs nee Kaszab, Istvan Gyertyan, Andras Egyed, Istvan Gacsalyi, Andras Bilkei-Gorzo, Katalin Pallagi, Katalin Szemeredi, Klara Kazo nee Daroczi
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Patent number: 4616025Abstract: New thiazolidine compounds of the formula (I) having anti-ulcer activity are disclosed: ##STR1## wherein Ar is a 2-furyl or a phenyl, naphthyl or pyridyl group optionally substituted by one or more C.sub.1-4 -alkyl, C.sub.1-4 -alkoxy, halo-C.sub.1-4 -alkoxy, dihalomethyl, trihalomethyl, hydroxyl or nitro groups or by a group of the formula (II), ##STR2## wherein Y is nitrogen or CH;Z is cyano or carbamoyl if Y is nitrogen, and represents a nitro group if Y is CH.Also disclosed are several processes for preparing the new compounds as well as pharmaceutical compositions and method of treatment employing same.Type: GrantFiled: March 16, 1984Date of Patent: October 7, 1986Assignee: Richter Gedeon Vegyeszeti Gyar RTInventors: Elemer Ezer, Kalman Harsanyi, Gyorgy Domany, Laszlo Szporny, Judit Matuz, Bela Hegedus, Katalin Pallagi, Istvan Szabadkai, Peter Tetenyi