Abstract: New compounds of the formula ##STR1## wherein R is hydrogen or methyl group,X y is a group of the formula ##STR2## and N IS AN INTEGER OF FROM 4 TO 10, ARE PREPARED BY ACYLATING THE APPROPRIATE LYSERGIC ACID-(3'-ALLYLOXY-2'-OXY-PROPYL)-AMIDE COMPOUNDS WITH CARBOXYLIC ACIDS OF 6 TO 12 CARBON ATOMS OR WITH THEIR REACTIVE DERIVATIVES. If desired, the new compounds can be converted into their pharmaceutically acceptable acid addition salts.The above compounds possess prolonged antidepressive activities.

Abstract: New compounds of the general formula (I) ##STR1## wherein R stands for hydrogen or methyl group,x y stands for a group of the formula ##STR2## and R.sub.1 stands for a group of the formula (III), (IV) or (V) ##STR3## wherein n is an integer from 4 to 10, ARE PREPARED BY ACYLATING A COMPOUND OF THE GENERAL FORMULA (II), ##STR4## wherein R and x y each have the same meanings as defined above, and R.sub.2 stands for a group of the formula (VI), (VII) or (VIII), ##STR5## with a C.sub.6-12 carboxylic acid or a C.sub.6-12 carboxylic acid halide. The new compounds of the general formula (I) and their acid addition salts can be used as antidepressants and antiserotonine agents with prolonged effects.