Patents by Inventor Katarzyna Crissy

Katarzyna Crissy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thermostable viral reverse transcriptase
    Patent number: 11807667
    Abstract: The present invention provides novel engineered polypeptides that support both reverse transcription and DNA amplification in manganese-independent reactions. The present invention also provides methods for amplifying template nucleic acids using such polypeptides. This invention addresses deficiencies in the current state of the art in nucleic acid amplification-based detection of template nucleic acids, especially RNA targets, including deficiencies in detection sensitivity, specificity, enzyme stability, inhibitor tolerance and time to result compared with manganese-dependent thermostable reverse transcriptases and two-enzyme solutions.
    Type: Grant
    Filed: April 30, 2019
    Date of Patent: November 7, 2023
    Assignee: QIAGEN BEVERLY, LLC.
    Inventors: Thomas William Schoenfeld, Ryan Charles Heller, Katarzyna Crissy, Suhman Chung
  • THERMOSTABLE VIRAL REVERSE TRANSCRIPTASE
    Publication number: 20210171580
    Abstract: The present invention provides novel engineered polypeptides that support both reverse transcription and DNA amplification in manganese-independent reactions. The present invention also provides methods for amplifying template nucleic acids using such polypeptides. This invention addresses deficiencies in the current state of the art in nucleic acid amplification-based detection of template nucleic acids, especially RNA targets, including deficiencies in detection sensitivity, specificity, enzyme stability, inhibitor tolerance and time to result compared with manganese-dependent thermostable reverse transcriptases and two-enzyme solutions.
    Type: Application
    Filed: April 30, 2019
    Publication date: June 10, 2021
    Inventors: Thomas William Schoenfeld, Ryan Charles Heller, Katarzyna Crissy, Suhman Chung