Patents by Inventor Katarzyna Ewa Rusin

Katarzyna Ewa Rusin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3-phenylpropionic acid derivatives
    Patent number: 7919515
    Abstract: The invention relates to new compounds, being 3-phenylpropionic acid derivatives of formula I wherein W represents COOH group or its bioisosters, or —COO—C1-C4-alkyl group; Y represents NH, N—C1-C10-alkyl, O, or S; Z represents NH, N—C1-C10-alkyl, N-aryl, N-heteroaryl, S, or O; X represents O, S, NH, N—C1-C10-alkyl, N-aryl, NSO2—C1-C10-alkyl, N—SO2-aryl, or N—SO2-heteroaryl; R, to R8 each independently represent hydrogen atom or a substituent defined in the description; A is as defined in the description; n represents an integer from 0 to 4, inclusive; and pharmaceutically acceptable salts thereof. The compounds are the ligands of PPAR-gamma receptor and are useful as medicaments.
    Type: Grant
    Filed: April 26, 2007
    Date of Patent: April 5, 2011
    Assignee: Adamed Sp. z o.o.
    Inventors: Zbigniew Majka, Katarzyna Ewa Rusin, Andrzej Wojciech Sawicki, Krzysztof Kurowski, Katarzyna Joanna Matusiewicz, Tomasz Stawinski, Daniel Sulikowski
  • 3-phenylpropionic acid derivatives
    Patent number: 7629370
    Abstract: The invention relates to a method of treatment and/or prophylaxis of diseases and conditions mediated by peroxysome proliferator-activated receptor gamma (PPAR?) in a mammal subject in need thereof, said method comprising administration to said mammal a compound of formula (I) or a pharmaceutically acceptable salt thereof in a therapeutically or prophylactically effective amount wherein in formula (I) W represents a COOH group or its bioisosters, or COO—C1-C4-alkyl group; Y represents NH or N—C1-C10-alkyl; Z represents NH, N—C1-C10-alkyl, N-aryl, N-heteroaryl, S, or O; X represents O, S, NH, N—C1-C10-alkyl, N-aryl, NSO2—C1-C10-alkyl, N—SO2-aryl, or N S02-heteroaryl; R1 to R6 each independently represents a hydrogen atom or a substituent defined in the description; A is as defined in the description; n represents an integer from 0 to 4, inclusive. The compounds of formula (I) are the ligands of PPAR-gamma receptor.
    Type: Grant
    Filed: March 6, 2007
    Date of Patent: December 8, 2009
    Assignee: Adamed Sp. z o.o.
    Inventors: Zbigniew Majka, Katarzyna Ewa Rusin, Dominik Daniel Kludkiewicz, Krzysztof Kurowski, Katarzyna Joanna Matusiewicz, Tomasz Stawinski, Daniel Sulikowski, Piotr Kowalczyk
  • 3-phenylpropionic acid derivatives
    Patent number: 7312338
    Abstract: The invention relates to new compounds, being 3-phenylpropionic acid derivatives of formula I wherein W represents COOH group or its bioisosters, or —COO—C1-C4-alkyl group; Y represents NH, N—C1-C10-alkyl, O, or S; Z represents NH, N—C1-C10-alkyl, N-aryl, N-heteroaryl, S, or O; X represents O, S, NH, N—C1-C10-alkyl, N-aryl, NSO2—C1-C10-alkyl, N—SO2-aryl, or N—SO2-heteroaryl; R1 to R8 each independently represent hydrogen atom or a substituent defined in the description; A is as defined in the description; n represents an integer from 0 to 4, inclusive; and pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: December 8, 2005
    Date of Patent: December 25, 2007
    Assignee: Adamed, Sp. z.o.o.
    Inventors: Zbigniew Majka, Katarzyna Ewa Rusin, Andrzej Wojciech Sawicki, Krzysztof Kurowski, Katarzyna Joanna Matusiewicz, Tomasz Stawinski, Daniel Sulikowski, Piotr Kowalczyk
  • 3-phenylpropionic acid derivatives
    Patent number: 7309791
    Abstract: The invention relates to new compounds, being 3-phenylpropionic acid derivatives of formula I wherein W represents COOH group or its bioisosters, or —COO—C1–C4-alkyl group; Y represents NH, N—C1–C10-alkyl, O, or S; Z represents NH, N—C1–C10-alkyl, N-aryl, N-heteroaryl, S, or O; X represents O, S, NH, N—C1–C10-alkyl, N-aryl, NSO2—C1–C10-alkyl, N—SO2-aryl, or N—SO2-heteroaryl; R1, to R6 each independently represent hydrogen atom or a substituent defined in the description; A is as defined in the description; n represents an integer from 0 to 4, inclusive; and pharmaceutically acceptable salts thereof. The compounds are the ligands of PPAR-gamma receptor and are useful as medicaments.
    Type: Grant
    Filed: January 12, 2006
    Date of Patent: December 18, 2007
    Assignee: Adamed Sp. z.o.o
    Inventors: Zbigniew Majka, Katarzyna Ewa Rusin, Dominik Daniel Kludkiewicz, Krzysztof Kurowski, Katarzyna Joanna Matusiewicz, Tomasz Stawinski, Daniel Sulikowski, Piotr Kowalczyk
  • 3-phenylpropionic acid derivatives
    Patent number: 7220766
    Abstract: The invention relates to new compounds, 3-phenylpropionic acid derivatives of formula (I) wherein W represents COOH group or its bioisosters, or —COO—C1–C4-alkyl group; Y represents NH, N—C1–C10-alkyl, O, or S; X represents O, S, NH, N—C1–C10-alkyl, N-aryl, NSO2—C1–C10-alkyl, N—SO2-aryl, or N—SO2-heteroaryl; R1 to R8 each independently represents hydrogen atom or a substituent defined in the description; A is as defined in the description; n represents an integer from 0 to 4, inclusive; and pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: January 12, 2006
    Date of Patent: May 22, 2007
    Assignee: ADAMED, Sp. z.o.o.
    Inventors: Zbigniew Majka, Katarzyna Ewa Rusin, Andrzej Wojciech Sawicki, Krzysztof Kurowski, Katarzyna Joanna Matusiewicz, Tomasz Stawinski, Daniel Sulikowski, Dominik Daniel Kludkiewicz, Piotr Kowalczyk