Patents by Inventor Katarzyna Florys

Katarzyna Florys has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Monoclonal antibodies against hemagglutinin of h5-serotype influenza viruses and their uses, hybridomas producing said antibodies, compositions and diagnostic kits
    Patent number: 10696737
    Abstract: The object of the invention are monoclonal antibodies against hemagglutinin of H5-serotype influenza viruses selected from the group comprising G-1-31-22, G-2-14-10, G-5-32-5, G-6-42-42, G-7-24-17 and G-7-27-18, having a broad application in immunoprophylaxis and immunotherapy of infections evoked by H5-serotype influenza viruses in humans and animals. The invention also provides hybridomas producing said antibodies, as well as compositions and diagnostic kits containing said antibodies for the detection and typing of H5-serotype influenza viruses and antibodies against H5-serotype influenza viruses in biological samples.
    Type: Grant
    Filed: September 11, 2017
    Date of Patent: June 30, 2020
    Assignees: SIEC BADAWCZA LUKASIEWICZ—INSTYTUT BIOTECHNOLOGII I ANTYBIOTYKOW, UNIWERSYTET GDANSKI
    Inventors: Violetta Sączyńska, Violetta Cecuda-Adamczewska, Anna Porębska, Katarzyna Florys, Anna Bierczyńska-Krzysik, Piotr Baran, Agnieszka Romanik-Chruścielewska, Grażyna Płucienniczak, Andrzej Płucienniczak, Piotr Borowicz, Krzysztof Kucharczyk, Boguslaw Szewczyk
  • MONOCLONAL ANTIBODIES AGAINST HEMAGGLUTININ OF H5-SEROTYPE INFLUENZA VIRUSES AND THEIR USES, HYBRIDOMAS PRODUCING SAID ANTIBODIES, COMPOSITIONS AND DIAGNOSTIC KITS
    Publication number: 20190352375
    Abstract: The object of the invention are monoclonal antibodies against hemagglutinin of H5-serotype influenza viruses selected from the group comprising G-1-31-22, G-2-14-10, G-5-32-5, G-6-42-42, G-7-24-17 and G-7-27-18, having a broad application in immunoprophyiaxis and immunotherapy of infections evoked by H5-serotype influenza viruses in humans and animals. The invention also provides hybridomas producing said antibodies, as well as compositions and diagnostic kits containing said antibodies for the detection and typing of H5-serotype influenza viruses and antibodies against H5-serotype influenza viruses in biological samples.
    Type: Application
    Filed: September 11, 2017
    Publication date: November 21, 2019
    Inventors: Violetta SACZYNSKA, Violetta CECUDA-ADAMCZEWSKA, Anna POREBSKA, Katarzyna FLORYS, Anna BIERCZYNSKA-KRZYSIK, Piotr BARAN, Agnieszka ROMANIK-CHRUSCIELEWSKA, Grazyna PLUCIENNICZAK, Andrzej PLUCIENNICZAK, Piotr BOROWICZ, Krzysztof KUCHARCZYK, Boguslaw SZEWCZYK
  • Influenza virus hemagglutinin protein as a vaccine antigen
    Patent number: 10398770
    Abstract: The invention relates to an influenza viruses hemagglutinin protein as a vaccine antigen against influenza viruses, in particular to a protein being a fragment of H5 hemagglutinin from highly pathogenic avian influenza virus (HPAIV) H5N1 strain, expressed in a bacterial expression system. The protein according to the invention is a potential ingredient of an anti-HPAIV H5N1 vaccine, administered to chickens parenterally or through mucous membranes in the presence of adjuvants. The object of the invention is also a method of obtaining the vaccine protein.
    Type: Grant
    Filed: June 24, 2015
    Date of Patent: September 3, 2019
    Assignee: INSTYTUT BIOTECHNOLOGII I ANTY-BIOTYKOW
    Inventors: Violetta Sączyńska, Agnieszka Romanik, Katarzyna Florys, Violetta Cecuda-Adamczewska, Malgorzata Kęsik-Brodacka, Grażyna Plucienniczak, Andrzej Plucienniczak, Piotr Borowicz, Natalia Lukasiewicz, Iwona Sokolowska, Diana Mikiewicz, Agnieszka Sobolewska, Piotr Baran, Józef Kapusta, Michal Odrowąż-Sypniewski, Anna Bierczy{dot over (n)}ska-Krzysik, Zenon Minta, Krzysztof Śmietanka, Monika Olszewska, Boguslaw Szewczyk
  • Influenza Virus Hemagglutinin Protein as a Vaccine Antigen
    Publication number: 20170165352
    Abstract: The invention relates to an influenza viruses hemagglutinin protein as a vaccine antigen against influenza viruses, in particular to a protein being a fragment of H5 hemagglutinin from highly pathogenic avian influenza virus (HPAIV) H5N1 strain, expressed in a bacterial expression system. The protein according to the invention is a potential ingredient of an anti-HPAIV H5N1 vaccine, administered to chickens parenterally or through mucous membranes in the presence of adjuvants. The object of the invention is also a method of obtaining the vaccine protein.
    Type: Application
    Filed: June 24, 2015
    Publication date: June 15, 2017
    Applicant: INSTYTUT BIOTECHNOLGII ANTY-BIOTYKOW
    Inventors: Violetta SACZYNSKA, Agnieszka ROMANIK, Katarzyna FLORYS, Violetta CECUDA-ADAMCZEWSKA, Malgorzata KESIK-BRODACKA, Grazyna PLUCIENNICZAK, Andrzej PLUCIENNICZAK, Piotr BOROWICZ, Natalia LUKASIEWICZ, Iwona SOKOLOWSKA, Diana MIKIEWICZ, Agnieszka SOBOLEWSKA, Piotr BARAN, Józef KAPUSTA, Michal ODROWAZ-SYP-NIEWSKI, Anna BIERCZYNSKA-KRZYSIK, Zenon MINTA, Krzysztof SMIETANKA, Monika OLSZEWSKA, Boguslaw SZEWCZYK
  • DNA vaccine, method of inducing the immune response, method of immunisation, antibodies specifically recognising the H5 haemagglutinin of an influenza virus and use of the DNA vaccine
    Patent number: 9505806
    Abstract: The object of the invention is a DNA vaccine, method of inducing the immune response, antibodies specifically recognizing the haemagglutinin H5 of an influenza virus and application of the DNA vaccine. According to the invention, one or two-fold immunization of hens with DNA vaccine containing a cDNA encoding the modified H5 haemagglutinin HA protein, i.e. with the deletion of the cleavage site between HA subunits (this provides for greater safety of the vaccines). Moreover, the encoding region of the HA is modified in such a way that protein production in the bird cells should achieve maximal yield. The main modification is codon optimization for the hens and deletion of the site of proteolytic cleavage between subunits HA1 and HA2.
    Type: Grant
    Filed: September 21, 2012
    Date of Patent: November 29, 2016
    Assignee: INSTYTUT BIOCHEMII I BIOFIZYKI PAN
    Inventors: Agnieszka Sirko, Anna Góra-Sochacka, Włodzimierz Zagórski-Ostoja, Anna Stachyra, Róza Sawicka, Bogusław Szewczyk, Beata Gromadzka, Violetta Sączyńska, Katarzyna Florys, Zenon Minta, Krzysztof Śmietanka
  • DNA VACCINE, METHOD OF INDUCING THE IMMUNE RESPONSE, METHOD OF IMMUNISATION, ANTIBODIES SPECIFICALLY RECOGNISING THE H5 HAEMAGGLUTININ OF AN INFLUENZA VIRUS AND USE OF THE DNA VACCINE
    Publication number: 20140255343
    Abstract: The object of the invention is a DNA vaccine, method of inducing the immune response, antibodies specifically recognising the haemagglutinin H5 of an influenza virus and application of the DNA vaccine. According to the invention, one or two-fold immunisation of hens with DNA vaccine containing a cDNA encoding the modified H5 haemagglutinin HA protein, i.e. with the deletion of the cleavage site between HA subunits (this provides for greater safety of the vaccines). Moreover, the encoding region of the HA is modified in such a way that protein production in the bird cells should achieve maximal yield. The main modification is codon optimisation for the hens and deletion of the site of proteolytic cleavage between subunits HA1 and HA2.
    Type: Application
    Filed: September 21, 2012
    Publication date: September 11, 2014
    Inventors: Agnieszka Sirko, Anna Gora-Sochacka, Wlodzimierz Zagorski-Ostoja, Anna Stachyra, Roza Sawicka, Boguslaw Szewczyk, Beata Gromadzka, Violetta Saczynska, Katarzyna Florys, Zenon Minta, Krzysztof Smietanka