Patents by Inventor Kate D. MEYER

Kate D. MEYER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of enhancing translation ability of RNA molecules, treatments, and kits
    Patent number: 11685923
    Abstract: The present invention relates to methods and a kit for enhancing the translation ability of an RNA molecule. The methods involve the use of an RNA molecule comprising a methylated adenosine residue in a 5? untranslated region (UTR). Also disclosed are methods for eIF4E-independent translation of an RNA molecule and treatment methods.
    Type: Grant
    Filed: February 19, 2020
    Date of Patent: June 27, 2023
    Assignee: CORNELL UNIVERSITY
    Inventors: Samie R. Jaffrey, Kate D. Meyer
  • METHODS AND KIT FOR CHARACTERIZING THE MODIFIED BASE STATUS OF A TRANSCRIPTOME
    Publication number: 20210284996
    Abstract: This invention relates to a method of characterizing the modified base status of a transcriptome, which involves contacting a transcriptome comprising one or more modified bases with an antibody specific to the modified bases under conditions effective to bind the antibody to the modified bases; isolating, from the transcriptome, a pool of RNA transcripts to which the antibody binds; and identifying isolated RNA transcripts that are present in a higher abundance in the isolated pool relative to the transcriptome, where each of the isolated RNA transcripts that are present in a higher abundance in the isolated pool together characterize the modified base status of the transcriptome. Also disclosed are a method of diagnosis or prognosis of a disease, a method of determining the effect of a treatment on modified base levels in RNA, and a kit for characterizing the modified base status of a transcriptome.
    Type: Application
    Filed: May 27, 2021
    Publication date: September 16, 2021
    Inventors: Samie R. JAFFREY, Kate D. MEYER, Christophber E. MASON
  • Methods and kit for characterizing the modified base status of a transcriptome
    Patent number: 11021703
    Abstract: This invention relates to a method of characterizing the modified base status of a transcriptome, which involves contacting a transcriptome comprising one or more modified bases with an antibody specific to the modified bases under conditions effective to bind the antibody to the modified bases; isolating, from the transcriptome, a pool of RNA transcripts to which the antibody binds; and identifying isolated RNA transcripts that are present in a higher abundance in the isolated pool relative to the transcriptome, where each of the isolated RNA transcripts that are present in a higher abundance in the isolated pool together characterize the modified base status of the transcriptome. Also disclosed are a method of diagnosis or prognosis of a disease, a method of determining the effect of a treatment on modified base levels in RNA, and a kit for characterizing the modified base status of a transcriptome.
    Type: Grant
    Filed: February 18, 2013
    Date of Patent: June 1, 2021
    Assignee: CORNELL UNIVERSITY
    Inventors: Samie R. Jaffrey, Kate D. Meyer, Christopher E. Mason
  • METHODS OF ENHANCING TRANSLATION ABILITY OF RNA MOLECULES, TREATMENTS, AND KITS
    Publication number: 20200199601
    Abstract: The present invention relates to methods and a kit for enhancing the translation ability of an RNA molecule. The methods involve the use of an RNA molecule comprising a methylated adenosine residue in a 5? untranslated region (UTR). Also disclosed are methods for eIF4E-independent translation of an RNA molecule and treatment methods.
    Type: Application
    Filed: February 19, 2020
    Publication date: June 25, 2020
    Inventors: Samie R. JAFFREY, Kate D. MEYER
  • Methods of enhancing translation ability of RNA molecules, treatments, and kits
    Patent number: 10584343
    Abstract: The present invention relates to methods and a kit for enhancing the translation ability of an RNA molecule. The methods involve the use of an RNA molecule comprising a methylated adenosine residue in a 5? untranslated region (UTR). Also disclosed are methods for eIF4E-independent translation of an RNA molecule and treatment methods.
    Type: Grant
    Filed: July 15, 2016
    Date of Patent: March 10, 2020
    Assignee: Cornell University
    Inventors: Samie R. Jaffrey, Kate D. Meyer
  • METHODS OF ENHANCING TRANSLATION ABILITY OF RNA MOLECULES, TREATMENTS, AND KITS
    Publication number: 20180195077
    Abstract: The present invention relates to methods and a kit for enhancing the translation ability of an RNA molecule. The methods involve the use of an RNA molecule comprising a methylated adenosine residue in a 5? untranslated region (UTR). Also disclosed are methods for eIF4E-independent translation of an RNA molecule and treatment methods.
    Type: Application
    Filed: July 15, 2016
    Publication date: July 12, 2018
    Inventors: Samie R. JAFFREY, Kate D. MEYER
  • METHODS AND KIT FOR CHARACTERIZING THE MODIFIED BASE STATUS OF A TRANSCRIPTOME
    Publication number: 20160060622
    Abstract: This invention relates to a method of characterizing the modified base status of a transcriptome, which involves contacting a transcriptome comprising one or more modified bases with an antibody specific to the modified bases under conditions effective to bind the antibody to the modified bases; isolating, from the transcriptome, a pool of RNA transcripts to which the antibody binds; and identifying isolated RNA transcripts that are present in a higher abundance in the isolated pool relative to the transcriptome, where each of said isolated RNA transcripts that are present in a higher abundance in the isolated pool together characterize the modified base status of the transcriptome. Also disclosed are a method of diagnosis or prognosis of a disease, a method of determining the effect of a treatment on modified base levels in RNA, and a kit for characterizing the modified base status of a transcriptome.
    Type: Application
    Filed: February 18, 2013
    Publication date: March 3, 2016
    Inventors: Samie R. JAFFREY, Kate D. MEYER, Christopher E. MASON