Patents by Inventor Kateri Hayashi DuBay

Kateri Hayashi DuBay has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and apparatus for assessing polypeptide aggregation
    Patent number: 8155888
    Abstract: A method of determining aggregation rate data predicting an aggregation rate of a polypeptide defined by an amino acid sequence, the method comprising determining a hydrophobicity value, a charge value, and at least one shape propensity value for said sequence; identifying one or more aggregation-influencing patterns within said sequence; determining a pattern value for the sequence responsive to said identifying; and determining said aggregation rate data by determining a weighted combination of said hydrophobicity value, said charge value, said at least one shape propensity value, said pattern value and at least one factor extrinsic to said amino acid sequence.
    Type: Grant
    Filed: March 8, 2010
    Date of Patent: April 10, 2012
    Assignee: Cambridge University Technical Services Ltd.
    Inventors: Christopher Dobson, Fabrizio Chiti, Jesus Zurdo, Kateri Hayashi DuBay, Michele Vendruscolo
  • METHOD AND APPARATUS FOR ASSESSING POLYPEPTIDE AGGREGATION
    Publication number: 20100261882
    Abstract: A method of determining aggregation rate data predicting an aggregation rate of a polypeptide defined by an amino acid sequence, the method comprising determining a hydrophobicity value, a charge value, and at least one shape propensity value for said sequence; identifying one or more aggregation-influencing patterns within said sequence; determining a pattern value for the sequence responsive to said identifying; and determining said aggregation rate data by determining a weighted combination of said hydrophobicity value, said charge value, said at least one shape propensity value, said pattern value and at least one factor extrinsic to said amino acid sequence.
    Type: Application
    Filed: March 8, 2010
    Publication date: October 14, 2010
    Applicant: Cambridge University Technical Services Ltd.
    Inventors: Christopher Doboson, Fabrizio Chiti, Jesus Zurdo, Kateri Hayashi DuBay, Michele Vendruscolo
  • Method and apparatus for assessing polypeptide aggregation
    Patent number: 7698070
    Abstract: A method of determining aggregation rate data predicting an aggregation rate of a polypeptide defined by an amino acid sequence, the method comprising determining a hydrophobicity value, a charge value, and at least one shape propensity value for said sequence; identifying one or more aggregation-influencing patterns within said sequence; determining a pattern value for the sequence responsive to said identifying; and determining said aggregation rate data by determining a weighted combination of said hydrophobicity value, said charge value, said at least one shape propensity value, said pattern value and at least one factor extrinsic to said amino acid sequence.
    Type: Grant
    Filed: May 4, 2006
    Date of Patent: April 13, 2010
    Assignee: Cambridge University Technical Services Ltd.
    Inventors: Christopher Dobson, Fabrizio Chiti, Jesus Zurdo, Kateri Hayashi DuBay, Michele Vendruscolo