Patents by Inventor Katey Rayner

Katey Rayner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR DETECTION, RISK ASSESSMENT AND TREATMENT OF DIABETES, OBESITY, AND INFLAMMATION
    Publication number: 20200147118
    Abstract: Provided are compounds and compositions associated with obesity, diabetes and inflammation and methods of treating the same.
    Type: Application
    Filed: November 9, 2018
    Publication date: May 14, 2020
    Inventors: Katey Rayner, Denuja Karunakaran, Ruth McPherson
  • Use of heat-shock protein 27 for cardiovascular disease prevention and treatment
    Patent number: 8343916
    Abstract: A method of reducing cholesterol in a subject is provided. The method may be used to decrease serum cholesterol and/or arterial wall cholesterol. The method comprises administering a therapeutically effective amount of heat shock protein 27 (HSP27), or a co-factor, variant or analogue thereof. The method may be used to treat, prevent or reverse cardiovascular disease (including atherosclerosis); to decrease atherosclerotic lesion formation or rupture; to decrease apoptosis within a plaque; to decrease macrophage accumulation; and/or to reverse the accumulation of atherosclerotic plaque mass in a subject. Kits and pharmaceutical compositions comprising HSP27 for preventing or treating of cardiovascular disease, such as atherosclerosis, are also provided.
    Type: Grant
    Filed: November 3, 2010
    Date of Patent: January 1, 2013
    Assignee: Ottawa Heart Institute Research Corporation
    Inventors: Edward R. M. O'Brien, Katey Rayner, Yong-Xiang Chen, Xiaoli Ma
  • Use of heat-shock protein 27 for cardiovascular disease prevention and treatment
    Patent number: 8343915
    Abstract: A method of preventing or treating cardiovascular disease is provided. The method comprises administering heat shock protein 27 (HSP27), a co-factor, variant or analogue thereof. The cardiovascular disease can include atherosclerosis. A pharmaceutical composition comprising HSP27 for use in the prevention or treatment of cardiovascular disease is also provided.
    Type: Grant
    Filed: August 11, 2008
    Date of Patent: January 1, 2013
    Assignee: Ottawa Heart Institute Research Corporation
    Inventors: Edward R. M. O'Brien, Katey Rayner, Yong-Xiang Chen, Xiaoli Ma
  • USE OF HEAT-SHOCK PROTEIN 27 FOR CARDIOVASCULAR DISEASE PREVENTION AND TREATMENT
    Publication number: 20110124568
    Abstract: A method of reducing cholesterol in a subject is provided. The method may be used to decrease serum cholesterol and/or arterial wall cholesterol. The method comprises administering a therapeutically effective amount of heat shock protein 27 (HSP27), or a co-factor, variant or analogue thereof. The method may be used to treat, prevent or reverse cardiovascular disease (including atherosclerosis); to decrease atherosclerotic lesion formation or rupture; to decrease apoptosis within a plaque; to decrease macrophage accumulation; and/or to reverse the accumulation of atherosclerotic plaque mass in a subject. Kits and pharmaceutical compositions comprising HSP27 for preventing or treating of cardiovascular disease, such as atherosclerosis, are also provided.
    Type: Application
    Filed: November 3, 2010
    Publication date: May 26, 2011
    Applicant: Ottawa Heart Institute Research Corporation
    Inventors: Edward R.M. O'Brien, Katey Rayner, Yong-Xiang Chen, Xiaoli Ma
  • Use of heat-shock protein 27 for cardiovascular disease prevention and treatment
    Publication number: 20090054340
    Abstract: A method of preventing or treating cardiovascular disease is provided. The method comprises administering heat shock protein 27 (HSP27), a co-factor, variant or analogue thereof. The cardiovascular disease can include atherosclerosis. A pharmaceutical composition comprising HSP27 for use in the prevention or treatment of cardiovascular disease is also provided.
    Type: Application
    Filed: August 11, 2008
    Publication date: February 26, 2009
    Applicant: Ottawa Heart Institute Research Corporation
    Inventors: Yong-Xiang Chen, Xiaoli Ma, Edward O'Brien, Katey Rayner