Abstract: A screen sharing and video conferencing method and system comprising a presenter device, one or more attendee devices and a streaming server for receiving and rebroadcasting video and audio streams from the presenter and the attendee devices. The presenter device and the attendee devices each comprise a browser-based video and audio streaming components configured to transmit camera video and microphone audio to the streaming server and playback video and audio streams from the streaming server. The presenter device further comprises an installed screen capture and system audio capture component configured to compress and transmit video data from a desktop and/or video source of the presenter device and to transmit system audio to the streaming server. The attendee devices further receive video and audio streams from the streaming server of camera, microphone, system audio and screen capture sources.