Patents by Inventor Katharine K. Duncan

Katharine K. Duncan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PYRAZOLE MAGL INHIBITORS
    Publication number: 20230219897
    Abstract: Provided herein are pyrazole compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of monoacylglycerol lipase (MAGL). Furthermore, the subject compounds and compositions are useful for the treatment of pain.
    Type: Application
    Filed: March 16, 2023
    Publication date: July 13, 2023
    Inventors: Cheryl A. GRICE, John J.M. WIENER, Olivia D. WEBER, Katharine K. DUNCAN
  • Pyrazole MAGL inhibitors
    Patent number: 11655217
    Abstract: Provided herein are pyrazole compounds and pharmaceutical compositions comprising the same. The compounds and compositions are useful as modulators of monoacylglycerol lipase (MAGL). Furthermore, the compounds and compositions are useful for the treatment of pain.
    Type: Grant
    Filed: May 22, 2018
    Date of Patent: May 23, 2023
    Assignee: H. LUNDBECK A/S
    Inventors: Cheryl A. Grice, John J. M. Wiener, Olivia D. Weber, Katharine K. Duncan
  • DUAL MAGL AND FAAH INHIBITORS
    Publication number: 20210386734
    Abstract: Provided herein are compounds and pharmaceutical compositions comprising said compounds useful as modulators of MAGL and/or FAAH. The subject compounds and compositions are useful for the treatment of pain and neurological disorders.
    Type: Application
    Filed: August 25, 2021
    Publication date: December 16, 2021
    Inventors: Cheryl A. Grice, Justin S. Cisar, Katharine K. Duncan, Yu Feng, John J.M. Wiener, Olivia D. Weber
  • Pyrazole MAGL inhibitors
    Patent number: 11149037
    Abstract: Provided herein are pyrazole compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of MAGL. Furthermore, the subject compounds and compositions are useful for the treatment of pain.
    Type: Grant
    Filed: May 22, 2018
    Date of Patent: October 19, 2021
    Assignee: H. LUNDBECK A/S
    Inventors: Cheryl A. Grice, Olivia D. Weber, Daniel J. Buzard, Michael B. Shaghafi, John J. M. Wiener, Justin S. Cisar, Katharine K. Duncan
  • Dual MAGL and FAAH inhibitors
    Patent number: 11129827
    Abstract: Provided herein are compounds and pharmaceutical compositions comprising said compounds useful as modulators of MAGL and/or FAAH. The subject compounds and compositions are useful for the treatment of pain and neurological disorders.
    Type: Grant
    Filed: June 4, 2019
    Date of Patent: September 28, 2021
    Assignee: Abide Therapeutics, Inc.
    Inventors: Cheryl A. Grice, Justin S. Cisar, Katharine K. Duncan, Yu Feng, John J. M. Wiener, Olivia D. Weber
  • PYRAZOLE MAGL INHIBITORS
    Publication number: 20210053960
    Abstract: Provided herein are pyrazole compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of monoacylglycerol lipase (MAGL). Furthermore, the subject compounds and compositions are useful for the treatment of pain.
    Type: Application
    Filed: May 22, 2018
    Publication date: February 25, 2021
    Inventors: Cheryl A. GRICE, John J.M. WIENER, Olivia D. WEBER, Katharine K. DUNCAN
  • Pyrazole MAGL inhibitors
    Patent number: 10927105
    Abstract: Provided herein are pyrazole compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of monoacylglycerol lipase (MAGL). Furthermore, the subject compounds and compositions are useful for the treatment of pain.
    Type: Grant
    Filed: June 12, 2020
    Date of Patent: February 23, 2021
    Assignee: LUNDBECK LA JOLLA RESEARCH CENTER, INC.
    Inventors: Cheryl A. Grice, John J. M. Wiener, Olivia D. Weber, Katharine K. Duncan
  • PYRAZOLE MAGL INHIBITORS
    Publication number: 20200087304
    Abstract: Provided herein are pyrazole compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of MAGL. Furthermore, the subject compounds and compositions are useful for the treatment of pain.
    Type: Application
    Filed: May 22, 2018
    Publication date: March 19, 2020
    Inventors: Cheryl A. GRICE, Olivia D. WEBER, Daniel J. BUZARD, Michael B. SHAGHAFI, John J.M. WIENER, Justin S. CISAR, Katharine K. DUNCAN
  • DUAL MAGL AND FAAH INHIBITORS
    Publication number: 20190282568
    Abstract: Provided herein are compounds and pharmaceutical compositions comprising said compounds useful as modulators of MAGL and/or FAAH. The subject compounds and compositions are useful for the treatment of pain and neurological disorders.
    Type: Application
    Filed: June 4, 2019
    Publication date: September 19, 2019
    Inventors: Cheryl A. Grice, Justin S. Cisar, Katharine K. Duncan, Yu Feng, John J.M. Wiener, Olivia D. Weber
  • Pyrazole compounds and methods of making and using same
    Patent number: 10385057
    Abstract: Provided herein are pyrazole compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of MAGL and/or FAAH. Furthermore, the subject compounds and compositions are useful for the treatment of, for example, pain.
    Type: Grant
    Filed: November 18, 2016
    Date of Patent: August 20, 2019
    Assignee: LUNDBECK LA JOLLA RESEARCH CENTER, INC.
    Inventors: Cheryl A. Grice, Todd K. Jones, Katharine K. Duncan, Olivia D. Weber, Justin S. Cisar, Jeffrey E. Merit
  • Dual MAGL and FAAH inhibitors
    Patent number: 10350205
    Abstract: Provided herein are compounds and pharmaceutical compositions comprising said compounds useful as modulators of MAGL and/or FAAH. The subject compounds and compositions are useful for the treatment of pain and neurological disorders.
    Type: Grant
    Filed: March 12, 2018
    Date of Patent: July 16, 2019
    Assignee: Abide Therapeutics, Inc.
    Inventors: Cheryl A. Grice, Justin S. Cisar, Katharine K. Duncan, Yu Feng, John J. M. Wiener, Olivia D. Weber
  • Pyrazole compounds and methods of making and using same
    Patent number: 10323038
    Abstract: Provided herein are pyrazole compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of MAGL and/or FAAH. Furthermore, the subject compounds and compositions are useful for the treatment of, for example, pain.
    Type: Grant
    Filed: November 18, 2016
    Date of Patent: June 18, 2019
    Assignee: ABIDE THERAPEUTICS, INC.
    Inventors: Cheryl A. Grice, Todd K. Jones, Katharine K. Duncan, Justin S. Cisar, Jeffrey E. Merit, Olivia D. Weber
  • Pyrazole MAGL inhibitors
    Patent number: 10266497
    Abstract: Provided herein are pyrazole compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of monoacylglycerol lipase (MAGL). Furthermore, the subject compounds and compositions are useful for the treatment of pain.
    Type: Grant
    Filed: May 22, 2018
    Date of Patent: April 23, 2019
    Assignee: ABIDE THERAPEUTICS, INC.
    Inventors: Cheryl A. Grice, John J. M. Wiener, Olivia D. Weber, Katharine K. Duncan
  • PYRAZOLE MAGL INHIBITORS
    Publication number: 20180339970
    Abstract: Provided herein are pyrazole compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of monoacylglycerol lipase (MAGL). Furthermore, the subject compounds and compositions are useful for the treatment of pain.
    Type: Application
    Filed: May 22, 2018
    Publication date: November 29, 2018
    Inventors: Cheryl A. GRICE, John J. M. WIENER, Olivia D. WEBER, Katharine K. DUNCAN
  • PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME
    Publication number: 20180327416
    Abstract: Provided herein are pyrazole compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of MAGL and/or FAAH. Furthermore, the subject compounds and compositions are useful for the treatment of, for example, pain.
    Type: Application
    Filed: November 18, 2016
    Publication date: November 15, 2018
    Inventors: Cheryl A. GRICE, Todd K. JONES, Katharine K. DUNCAN, Justin S. CISAR, Jeffrey E. MERIT, Olivia D. WEBER
  • DUAL MAGL AND FAAH INHIBITORS
    Publication number: 20180256566
    Abstract: Provided herein are compounds and pharmaceutical compositions comprising said compounds useful as modulators of MAGL and/or FAAH. The subject compounds and compositions are useful for the treatment of pain and neurological disorders.
    Type: Application
    Filed: March 12, 2018
    Publication date: September 13, 2018
    Inventors: Cheryl A. GRICE, Justin S. CISAR, Katharine K. DUNCAN, Yu FENG, John J.M. WIENER, Olivia D. WEBER
  • Salvinorin derivatives and uses thereof
    Patent number: 8492564
    Abstract: The invention features salvinorin compositions that are selective for kappa opioid receptors; methods of treating mania by using a selective kappa receptor agonist; and methods of treating mood disorders, such as depressive disorders and manic disorders, using salvinorin compositions.
    Type: Grant
    Filed: December 14, 2009
    Date of Patent: July 23, 2013
    Assignees: The McLean Hospital Corporation, Temple University School of Medicine
    Inventors: Cecile Beguin, Justin Stephen Potuzak, Thomas Anthony Munro, Katharine K. Duncan, William A. Carlezon, Bruce M. Cohen, Lee-yuan Liu-Chen