Abstract: Method and compositions are described for treating an acute medical condition in a subject with a lipophilic agent, where the lipophilic agent is formulated in an oil, the formulation optionally including benzyl alcohol. The formulation is suited for administering the lipophilic agent subcutaneously to achieve rapid uptake by the blood and thereafter sustained delivery.

Abstract: The present invention provides methods of conferring protection on a population of cells in a subject following an acute degenerative event, comprising: administering an effective amount of the compound in an oil formulation over a course that includes at least one dose within a time that is effectively proximate to the ischemic event, so as to confer protection on the population of cells.

Abstract: The present invention provides methods of conferring protection on a population of cells associated with ischemia in a subject following an ischemic event, comprising: (a) providing a sulfated form of an estrogen compound intravenously; and (b) administering the effective amount of the compound over a course that includes at least one dose within a time that is effectively proximate to the ischemic event, so as to confer protection on the population of cells. Examples of ischemic events treatable according to the invention are cerebrovascular disease or stroke, subarachnoid subhemorrhage, myocardial infarct, surgery and trauma.

Abstract: Method and compositions are described for treating an acute medical condition in a subject with a lipophilic agent, where the lipophilic agent is formulated in an oil, the formulation optionally including benzyl alcohol. The formulation is suited for administering the lipophilic agent subcutaneously to achieve rapid uptake by the blood and thereafter sustained delivery.

Abstract: The present invention provides methods of conferring protection on a population of cells associated with ischemia in a subject following an ischemic event, comprising: (a) providing an estrogen compound; and (b) administering the effective amount of the compound over a course that includes at least one dose within a time that is effectively proximate to the ischemic event, so as to confer protection on the population of cells. Novel methods are provided for the delivery of an estrogen compound. Examples of ischemic events treatable according to the invention are cerebrovascular disease or stroke, subarachnoid subhemorrhage, myocardial infarct, surgery and trauma. A method of treating ischemic damage utilizing non-sex hormones is also provided.

Abstract: The present invention provides methods of conferring protection on a population of cells associated with ischemia in a subject following an ischemic event, comprising: (a) providing an estrogen compound; and (b) administering the effective amount of the compound over a course that includes at least one dose within a time that is effectively proximate to the ischemic event, so as to confer protection on the population of cells. Novel methods are provided for the intravenous administration of an estrogen compound. Examples of ischemic events treatable according to the invention are cerebrovascular disease or stroke, subarachnoid subhemorrhage, myocardial infarct, surgery and trauma. A method of treating ischemic damage utilizing non-sex hormones is also provided.

Abstract: The invention comprises methods for conferring a cytoprotective effect on a population of cells, such as providing a polycyclic phenolic compound in a physiologically acceptable formulation, and administering the formulation in an effective dose to the population of cells.

Abstract: Androgens and their derivates and analogs, such as anabolic agents, are characterized by at least one substituent or substituent grouping with radical trapping properties.