Patents by Inventor Katherine Delaria

Katherine Delaria has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF RENATURATION OF RECOMBINANT PROTEINS
    Publication number: 20110034678
    Abstract: The present invention provides large-scale methods for renaturation of proteins comprising adding a solution of denatured, chemically modified or reduced proteins to a refolding buffer containing sulfate derived from H2SO4 and/or MgSO4 in the presence of guanidine. The present invention further provides methods of isolating a refolded protein at a concentration of about 0.4 to 3.0 gm/L by using a hydrophobic interaction chromatography (HIC) column.
    Type: Application
    Filed: March 12, 2010
    Publication date: February 10, 2011
    Applicant: AEROVANCE, INC.
    Inventors: Wayne Froland, Katherine Delaria, David Boisvert, Robert Kuhn
  • Human bikunin
    Patent number: 7452859
    Abstract: The instant invention provides for proteins, polypeptides, nucleic acid sequences, constructs, expression vectors, host cells, pharmaceutical compositions of, and methods for using human placental bikunin, serine protease inhibitor domains, and fragments thereof.
    Type: Grant
    Filed: March 27, 2006
    Date of Patent: November 18, 2008
    Assignee: Aerovance, Inc.
    Inventors: Paul P. Tamburini, Gary Davis, Katherine A. Delaria, Christopher W. Marlor, Daniel K. Muller
  • Human bikunin
    Publication number: 20060172946
    Abstract: The instant invention provides for proteins, polypeptides, nucleic acid sequences, constructs, expression vectors, host cells, pharmaceutical compositions of, and methods for using human placental bikunin, serine protease inhibitor domains, and fragments thereof.
    Type: Application
    Filed: March 27, 2006
    Publication date: August 3, 2006
    Inventors: Paul Tamburini, Gary Davis, Katherine Delaria, Christopher Marlor, Daniel Muller
  • Human bikunin
    Patent number: 7019123
    Abstract: The instant invention provides for proteins, polypeptides, nucleic acid sequences, constructs, expression vectors, host cells, pharmaceutical compositions of, and methods for using human placental bikunin, serine protease inhibitor domains, and fragments thereof
    Type: Grant
    Filed: October 10, 2001
    Date of Patent: March 28, 2006
    Assignee: Bayer Corporation
    Inventors: Paul P. Tamburini, Gary Davis, Katherine A. Delaria, Christopher W. Marlor, Daniel K. Muller
  • Human bikunin
    Publication number: 20030194398
    Abstract: The instant invention provides for proteins, polypeptides, nucleic acid sequences, constructs, expression vectors, host cells, pharmaceutical compositions of, and methods for using human placental bikunin, serine protease inhibitor domains, and fragments thereof.
    Type: Application
    Filed: October 10, 2001
    Publication date: October 16, 2003
    Inventors: Paul P. Tamburini, Gary Davis, Katherine A. Delaria, Christopher W. Marlor, Daniel K. Muller
  • Human bikunin
    Patent number: 6583108
    Abstract: The instant invention provides for proteins, polypeptides, nucleic acid sequences, constructs, expression vectors, host cells, pharmaceutical compositions of, and methods for using human placental bikunin, serine protease inhibitor domains, and fragments thereof.
    Type: Grant
    Filed: August 31, 1998
    Date of Patent: June 24, 2003
    Assignee: Bayer Corporation
    Inventors: Paul P. Tamburini, Gary Davis, Katherine A. Delaria, Christopher W. Marlor, Daniel K. Muller
  • Cytotoxic T-lymphocyte antigen as cysteine protease inhibitor
    Patent number: 5973110
    Abstract: Disclosed are molecules which inhibit the proteolytic activity of cysteine proteases such as Cathepsin H, Cathepsin L and papain, and methods for using molecules which have the biological properties of cytotoxic T-lymphocyte antigen for inhibiting cysteine proteases and inhibiting proteoglycan degradation.
    Type: Grant
    Filed: May 18, 1995
    Date of Patent: October 26, 1999
    Assignee: Bayer Corporation
    Inventors: Daniel Muller, Katherine Delaria, Linda Wallace, Elise Brownell
  • Cytotoxic T-lymphocyte antigen as cysteine protease inhibitor
    Patent number: 5962633
    Abstract: Disclosed are molecules which inhibit the proteolytic activity of cysteine proteases such as Cathespin H, Cathespin L and papain, and methods for using molecules which have the biological properties of cytotoxic T-lymphoyte antigen for inhibiting cysteins proteases and inhibiting proteolglycan degradation.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: October 5, 1999
    Assignee: Bayer Corporation
    Inventors: Daniel Muller, Katherine Delaria, Linda Wallace, Elise Brownell
  • Secretory leukocyte protease inhibitor as an inhibitor of tryptase
    Patent number: 5633227
    Abstract: This invention concerns methods of treating mast-cell mediated conditions in mammals, the methods comprising administering to the mammals pharmacologically active fragments or muteins of SLPI; methods of treating asthma or allergic rhinitis in mammals, the methods comprising administering to the mammals SLPI or pharmacologically active fragments or muteins thereof; methods for inhibiting tryptase; methods for identifying inhibitors of tryptase; and certain fragments and muteins of SLPI.
    Type: Grant
    Filed: September 12, 1994
    Date of Patent: May 27, 1997
    Assignee: Miles, Inc.
    Inventors: Daniel K. Muller, Elise Brownell, Katherine A. Delaria