Patents by Inventor Katherine E. Brighty

Katherine E. Brighty has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Penem prodrugs
    Patent number: 7795243
    Abstract: Orally bioavailable prodrugs of sulopenem, e.g., and solvates and hydrates thereof, preparation thereof, formulation thereof, and use to treat and prevent infection in mammals such as humans. This abstract is not limiting to the invention.
    Type: Grant
    Filed: June 28, 2007
    Date of Patent: September 14, 2010
    Assignee: Pfizer, Inc.
    Inventors: Katherine E. Brighty, Anthony Marfat, Dale G. McLeod, John P. O'Donnell
  • PENEM PRODRUGS
    Publication number: 20090042853
    Abstract: Orally bioavailable prodrugs of sulopenem, e.g., and solvates and hydrates thereof preparation thereof formulation thereof and use to treat and prevent infection in mammals such as humans. This abstract is not limiting to the invention.
    Type: Application
    Filed: June 30, 2008
    Publication date: February 12, 2009
    Inventors: Katherine E. BRIGHTY, Anthony Marfat, Dale G. Mcleod, John P. O'Donnell
  • PENEM PRODRUGS
    Publication number: 20080009474
    Abstract: Orally bioavailable prodrugs of sulopenem, e.g., and solvates and hydrates thereof, preparation thereof, formulation thereof, and use to treat and prevent infection in mammals such as humans. This abstract is not limiting to the invention.
    Type: Application
    Filed: June 28, 2007
    Publication date: January 10, 2008
    Inventors: Katherine E. BRIGHTY, Anthony Marfat, Dale G. McLeod, John P. O'Donnell
  • Hygromycin derivatives
    Patent number: 6562792
    Abstract: The present invention relates to compounds of the formula 1 and to pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein X, Y, V, W1, W2, Z1 and Z2 are as defined herein. The invention also relates to pharmaceutical compositions containing the above compounds and to methods of treating bacterial and protozoal infections in mammals by administering the above compounds.
    Type: Grant
    Filed: October 20, 2000
    Date of Patent: May 13, 2003
    Assignee: Pfizer Inc.
    Inventors: Katherine E. Brighty, Robert G. Linde, Takushi Kaneko, Matthew M. Hayward
  • C-4 substituted macrolide antibiotics
    Patent number: 6300316
    Abstract: This invention relates to compounds of the formula and to pharmaceutically acceptable salts thereof. The compounds of formula 1 are potent antibacterial and antiprotozoal agents that may be used to treat various bacterial and protozoal infections and disorders related to such infections. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and to methods of treating bacterial and protozoal infections by administering the compounds of formula 1.
    Type: Grant
    Filed: August 23, 1999
    Date of Patent: October 9, 2001
    Assignee: Pfizer Inc
    Inventors: Katherine E. Brighty, Takushi Kaneko, Robert G. Linde, II, Hiroko Masamune, Paul R. McGuirk, Wei-Guo Su, Yong-Jin Wu, Bingwei V. Yang
  • Aza bicyclo[3,1,0]hexane intermediates useful in the synthesis of quinolones
    Patent number: 5475116
    Abstract: This invention relates to certain azabicyclo hexane intermediates and processes for making and using the azabicyclo hexane intermediates. The intermediates are useful in the synthesis of quinolone antibacterial agents.
    Type: Grant
    Filed: April 29, 1994
    Date of Patent: December 12, 1995
    Assignee: Pfizer Inc.
    Inventors: Katherine E. Brighty, Tamim F. Braish
  • 3-aza-bicyclo[3.1.0]hexanes which are intermediates for anti-bacterial azabicyclo quinolone carboxylic acids
    Patent number: 5391763
    Abstract: Quinolone carboxylic acids 7 -substituted by azabicyclo groups have antibacterial activity.
    Type: Grant
    Filed: August 26, 1993
    Date of Patent: February 21, 1995
    Assignee: Pfizer Inc.
    Inventor: Katherine E. Brighty
  • Azatricyclo carboxylic acids useful as anti-bacterial agents
    Patent number: 5266569
    Abstract: Quinolone carboxylic acids 7-substituted by azabicyclo groups have antibacterial activity.
    Type: Grant
    Filed: February 2, 1993
    Date of Patent: November 30, 1993
    Assignee: Pfizer Inc.
    Inventor: Katherine E. Brighty
  • Anti-bacterial azabicyclo quinolone carboxylic acids
    Patent number: 5229396
    Abstract: Quinolone carboxylic acids 7-substituted by azabicyclo groups have antibacterial activity.
    Type: Grant
    Filed: July 24, 1992
    Date of Patent: July 20, 1993
    Assignee: Pfizer Inc.
    Inventor: Katherine E. Brighty
  • Thiazolyl and oxazolyl[5,4-c]piperidyl-substituted quinolone-carboxylic acid and related analogs thereof having antibacterial properties are disclosed
    Patent number: 5214051
    Abstract: Thiazolyl and oxazolyl [5,4-c] piperidyl-substituted quinolone-carboxylic acids and related analogs thereof having antibacterial properties are disclosed.
    Type: Grant
    Filed: May 16, 1991
    Date of Patent: May 25, 1993
    Assignee: Pfizer Inc.
    Inventors: Katherine E. Brighty, John A. Lowe, III, Paul R. McGuirk
  • Azabicyclo quinolone and naphthyridinone carboxylic acids
    Patent number: 5164402
    Abstract: Quinolone carboxylic acids 7-substituted by azabicyclo groups have antibacterial activity.
    Type: Grant
    Filed: February 4, 1991
    Date of Patent: November 17, 1992
    Assignee: Pfizer Inc
    Inventor: Katherine E. Brighty
  • Heterocycylic-substituted quinoline-carboxylic acids
    Patent number: 5037834
    Abstract: 1-Substituted-6-fluoro-7-heterocyclic-1,4-dihydroquino-1-(or dihydronaphthyridin)-4-one carboxylic acids have antibacterial properties. The 7-heterocyclic group is a bicyclic group, one of the rings of which is saturated and the other ring of which is unsaturated.
    Type: Grant
    Filed: August 1, 1989
    Date of Patent: August 6, 1991
    Assignee: Pfizer Inc.
    Inventors: Katherine E. Brighty, John A. Lowe, III, Paul R. McGuirk
  • Process for penem derivatives
    Patent number: 4782145
    Abstract: An efficient process for converting readily available 4-acetoxy-2-azetidinones to allyl 2-thioxopenam-3-carboxylates, intermediates useful for the synthesis of penem antibiotics.
    Type: Grant
    Filed: June 2, 1986
    Date of Patent: November 1, 1988
    Assignee: Pfizer Inc.
    Inventors: Katherine E. Brighty, David L. Lindner
  • Process for the synthesis of penems
    Patent number: 4782146
    Abstract: A process for the synthesis of penems from azetidinones via 1-aza-4,5-dithiabicyclo[4.2.0]oct-2-en-8-one-2-carboxylate esters.
    Type: Grant
    Filed: June 16, 1987
    Date of Patent: November 1, 1988
    Assignee: Pfizer Inc.
    Inventor: Katherine E. Brighty
  • 1-aza-4,5-dithiabicyclo [4.2.0] oct-2-en-8-one-2 carboxylate esters
    Patent number: 4695626
    Abstract: 1-aza-4,5-dithiabicyclo [4.2.0] oct-2-en-8-one-2 carboxylate ester intermediates useful for the synthesis of penems.
    Type: Grant
    Filed: July 29, 1986
    Date of Patent: September 22, 1987
    Assignee: Pfizer Inc.
    Inventor: Katherine E. Brighty