Abstract: The disclosure provides compounds of formula I, II, III, IV, and V, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.

Abstract: A bracelet for counting calories is formed by a plurality of counting beads each having an aperture there through. A monofilament line is threaded in a looping manner through the aperture of each counting bead such that the line overlaps itself within the aperture. Using this configuration and a freespace along the line, the counting beads may be selectively slid along the length of the line and retained in position, permitting the wearer to keep track of daily calorie intake by the movement and placement of the beads. A plurality of summing beads are also included and these are strung one per every five counting beads. This way, the counting beads are assigned an associative value of 100 calories per bead and are subdivided into groups of 500 calories by inter-positioned summing beads.

Abstract: A bracelet for counting calories is formed by a plurality of counting beads each having an aperture there through. A monofilament line is threaded in a looping manner through the aperture of each counting bead such that the line overlaps itself within the aperture. Using this configuration and a freespace along the line, the counting beads may be selectively slid along the length of the line and retained in position, permitting the wearer to keep track of daily calorie intake by the movement and placement of the beads. A plurality of summing beads are also included and these are strung one per every five counting beads. This way, the counting beads are assigned an associative value of 100 calories per bead and are subdivided into groups of 500 calories by inter-positioned summing beads.