Patents by Inventor Katherine KOZAK

Katherine KOZAK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • High Throughput Multiparametric Immune Cell Engager Screening Assay
    Publication number: 20230341379
    Abstract: The present disclosure provides methods and systems for high throughput assays for testing immune cell engager molecules and potential immune cell engager molecules. In some embodiments, multiple parameters, for example, in connection with engagement of tumor cells by immune cells such as T cells and in connection with tumor cell death, may be analyzed from the same samples in the assays, and, in some cases, may be analyzed simultaneously. In some embodiments, the methods and systems allow for determining the kinetics of various parameters.
    Type: Application
    Filed: March 23, 2023
    Publication date: October 26, 2023
    Applicant: Genentech Inc.
    Inventors: Katherine Kozak, Josefa dela Cruz Chuh
  • Cysteine Engineered Antibodies and Conjugates
    Publication number: 20230130874
    Abstract: Cysteine engineered antibodies comprising a free cysteine amino acid in the heavy chain or light chain are prepared by mutagenizing a nucleic acid sequence of a parent antibody and replacing one or more amino acid residues by cysteine to encode the cysteine engineered antibody; expressing the cysteine engineered antibody; and isolating the cysteine engineered antibody.
    Type: Application
    Filed: May 13, 2022
    Publication date: April 27, 2023
    Applicant: Genentech, Inc.
    Inventors: Sunil Bhakta, Hans Erickson, Jagath R. Junutula, Katherine Kozak, Rachana Ohri, Thomas Harden Pillow
  • CYSTEINE ENGINEERED ANTIBODIES AND CONJUGATES
    Publication number: 20200017601
    Abstract: Cysteine engineered antibodies comprising a free cysteine amino acid in the heavy chain or light chain are prepared by mutagenizing a nucleic acid sequence of a parent antibody and replacing one or more amino acid residues by cysteine to encode the cysteine engineered antibody; expressing the cysteine engineered antibody; and isolating the cysteine engineered antibody.
    Type: Application
    Filed: March 14, 2019
    Publication date: January 16, 2020
    Applicant: Genentech, Inc.
    Inventors: Sunil BHAKTA, Hans ERICKSON, Jagath R. JUNUTULA, Katherine KOZAK, Rachana OHRI, Thomas PILLOW
  • Cysteine engineered antibodies and conjugates
    Patent number: 10077318
    Abstract: Cysteine engineered antibodies comprising a free cysteine amino acid in the heavy chain or light chain are prepared by mutagenizing a nucleic acid sequence of a parent antibody and replacing one or more amino acid residues by cysteine to encode the cysteine engineered antibody; expressing the cysteine engineered antibody; and isolating the cysteine engineered antibody.
    Type: Grant
    Filed: September 11, 2015
    Date of Patent: September 18, 2018
    Assignee: Genentech, Inc.
    Inventors: Sunil Bhakta, Hans Erickson, Jagath R. Junutula, Katherine Kozak, Rachana Ohri, Thomas Pillow
  • CYSTEINE ENGINEERED ANTIBODIES AND CONJUGATES
    Publication number: 20160130358
    Abstract: Cysteine engineered antibodies comprising a free cysteine amino acid in the heavy chain or light chain are prepared by mutagenizing a nucleic acid sequence of a parent antibody and replacing one or more amino acid residues by cysteine to encode the cysteine engineered antibody; expressing the cysteine engineered antibody; and isolating the cysteine engineered antibody.
    Type: Application
    Filed: September 11, 2015
    Publication date: May 12, 2016
    Applicant: Genentech, Inc.
    Inventors: Sunil BHAKTA, Hans ERICKSON, Jagath R. JUNUTULA, Katherine KOZAK, Rachana OHRI, Thomas PILLOW