Abstract: A composition having effective broad spectrum preservation activity comprising benzyl alcohol, salicylic acid, sorbic acid and a compound selected from the group consisting of 1,3-propanediol, glycerin and combinations thereof.

Abstract: A composition comprising coated particles of a salt of pyrithione selected from the group consisting of monovalent and polyvalent pyrithione salts, and combinations thereof, partially or fully coated with a lipophilic agent. The composition is characterized by enhanced anti-fungal and anti-dandruff efficacy in shampoos. Also disclosed is a personal care composition, preferably a shampoo, containing a topical carrier and coated particles of a salt of pyrithione selected from the group consisting of monovalent and polyvalent pyrithione salts, and combinations thereof, partially or fully coated with a lipophilic agent.

Abstract: The present invention is directed to a composition for treating recirculating water systems, comprising: (1) a biocidal effective amount of a first nonoxidizing biocide comprising biguanide; and (2) a biocidal effective amount of a second nonoxidizing biocide comprising dibromonitrilopropionamide (DBNPA); wherein the composition is substantially free from oxidants. The present invention is also directed to a method of controlling the growth of microorganisms in recirculating water systems, comprising the step of treating the recirculating water systems with the above composition.

Abstract: A composition having effective broad spectrum preservation activity comprising benzyl alcohol, salicylic acid, sorbic acid and a compound selected from the group consisting of 1,3-propanediol, glycerin and combinations thereof.

Abstract: A composition having effective broad spectrum preservation activity comprising a mixture of caprylyl glycol or one or more analogs thereof, or mixtures thereof with a preservative selected from the group consisting of: (1) chloroxylenol and 2-phenoxyethanol, (2) chloroxylenol and chlorphenesin, (3) chlorphenesin and 2-phenoxyethanol, and (4) chloroxylenol, chlorphenesin and 2-phenoxyethanol.

Abstract: Disclosed is a formulation and method for the treatment of fungal infections of the nail (onychomycosis) utilizing a topical composition comprising zinc pyrithione, a solubilizer for the zinc pyrithione, a film former, and a volatile solvent. The formulation is preferably in the form of a lacquer. The composition containing the metal pyrithione complex is topically applied to the infected nail preferably as a nail polish or lacquer which may be applied with a dropper, swab or the like to the afflicted nail surface. The treatment can be done at least two times a day, with a course of treatment lasting from several weeks to several months or until a cure is effected or a significant reduction of the infection is achieved.

Abstract: The present invention is directed to a composition for reducing the levels of microorganisms in recreational water systems, comprising: (1) a biocidal effective amount of dibromonitrilopropionamide (DBNPA); (2) optionally, a biocidal effective amount of an algaecide selected from the group consisting of didecyldimethylammonium chloride (DDAC), zinc, and copper; and (3) optionally, a compound capable of in situ activation to form an oxidizing agent; wherein the composition is effective for reducing the levels of microorganisms in recreational water systems. The present invention is also directed to a method of controlling the growth of microorganisms in recreational water systems, comprising the step of providing the above composition; and adding the composition to a recreational water system.

Abstract: The present invention is directed to a composition for treating recirculating water systems, comprising: (1) a biocidal effective amount of a first nonoxidizing biocide comprising biguanide; and (2) a biocidal effective amount of a second nonoxidizing biocide comprising dibromonitrilopropionamide (DBNPA); wherein the composition is substantially free from oxidants. The present invention is also directed to a method of controlling the growth of microorganisms in recirculating water systems, comprising the step of treating the recirculating water systems with the above composition.

Abstract: Disclosed is a method for delivering excess zinc to eukaryotic cells to inhibit the metabolism of the cell, the method comprising treating the cells with a zinc ionophoric that is capable of delivering a zinc ion across a cellular membrane wherein the minimum inhibitory concentration (MIC) of the zinc ionophoric material is less than about 500 ppm. Further disclosed is a method for delivering excess zinc to eukaryotic cells to inhibit the metabolism of the cell, the method comprising treating the cells with a zinc ionophoric material that is capable of delivering a zinc ion across a cellular membrane wherein the zinc ionophoric material is in combination with a zinc containing material and further wherein there is an increase in an intracellular zinc level by 1.5 fold more than would occur in the absence of the zinc ionophoric material.

Abstract: This invention is directed to a detergent composition comprising the microbial lipase SD2 and dodecylbenzene sulfonate. In the detergent composition, the lipase SD2 is characterized by having (i) optimum pH for activity of about 8.+-.0.5; (ii) an optimum temperature for activity of about 30.degree. to 55.degree. C. and (iii) a molecular weight as measured by gel permeation chromatography of about 8.8.times.10.sup.4.

Abstract: A water monitoring system, and more particularly a method and kit for detecting the presence of live undesirable or indicator microorganisms in water after treatment of the water with chlorine or bromine.

Abstract: Water monitoring systems, and more specifically, to a method and kit for detecting the presence of only living undesirable or indicator microorganisms in water after treatment of the water with chlorine or bromine.