Patents by Inventor Katherine Tooley

Katherine Tooley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PAN-CANCER T CELL EXHAUSTION GENES
    Publication number: 20210130438
    Abstract: The present invention provides novel pan-cancer T cell exhaustion regulators. CXCR6 expressed in CD8+ T cells was specifically identified as regulating anti-tumor immunity. Modulating CXCR6-CXCL16 interaction is useful in modulating anti-tumor immunity. The identified genes may be modulated in T cells for use in adoptive cell transfer. The identified genes may be modulated in vivo.
    Type: Application
    Filed: October 28, 2020
    Publication date: May 6, 2021
    Inventors: Livnat Jerby-Arnon, Ana Carrizosa Anderson, Aviv Regev, Katherine Tooley, Vijay K. Kuchroo