Patents by Inventor Katherine Wright
Katherine Wright has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11763240Abstract: Some embodiments provide a non-transitory machine-readable medium that stores a program executable by a device. The program identifies a set of visualizations associated with the user. The program further determines, for each visualization in the set of visualizations, a score associated with changes in the visualization. The program also determines a subset of the set of visualizations based on the set of scores. The program further provides to the user notifications associated with the subset of the set of visualizations.Type: GrantFiled: October 12, 2020Date of Patent: September 19, 2023Assignee: BUSINESS OBJECTS SOFTWARE LTDInventors: Jiandong Shi, Katherine Wright, Flavia Moser, Ahmet Yoldemir
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Patent number: 11747421Abstract: The present application provides a system and method for quantifying perfusion using a dictionary matching approach. In some aspects, the method comprises performing a predetermined pulse sequence using an MRI system to acquire MRI data from the subject after having delivered a dose of a contrast agent to the subject. The method also includes comparing the MRI data to a dictionary to determine perfusion information, and generating, using the perfusion information, a report indicative of perfusion within the subject.Type: GrantFiled: May 20, 2019Date of Patent: September 5, 2023Assignee: Case Western Reserve UniversityInventors: Vikas Gulani, Satyam Ghodasara, Katherine Wright, Nicole Seiberlich, Mark A. Griswold
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Patent number: 11340325Abstract: Apparatus, methods, and other embodiments associated with NMR fingerprinting are described. One example NMR apparatus includes an NMR logic that repetitively and variably samples a (k, t, E) space associated with an object to acquire a set of NMR signals that are associated with different points in the (k, t, E) space. Sampling is performed with t and/or E varying in a non-constant way. Sampling is performed in response to a diffusion-weighted double-echo pulse sequence. Sampling acquires transient-state signals of the double-echo sequence. The NMR apparatus may also include a signal logic that produces an NMR signal evolution from the NMR signals, and a characterization logic that characterizes a resonant species in the object as a result of comparing acquired signals to reference signals.Type: GrantFiled: May 6, 2019Date of Patent: May 24, 2022Assignee: Case Western Reserve UniversityInventors: Mark Griswold, Vikas Gulani, Dan Ma, Yun Jiang, Katherine Wright
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Publication number: 20220114526Abstract: Some embodiments provide a non-transitory machine-readable medium that stores a program executable by a device. The program identifies a set of visualizations associated with the user. The program further determines, for each visualization in the set of visualizations, a score associated with changes in the visualization. The program also determines a subset of the set of visualizations based on the set of scores. The program further provides to the user notifications associated with the subset of the set of visualizations.Type: ApplicationFiled: October 12, 2020Publication date: April 14, 2022Inventors: Jiandong Shi, Katherine Wright, Flavia Moser, Ahmet Yoldemir
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Patent number: 11096999Abstract: There are provided antigens, vectors encoding the antigens, and antibodies and other binding compounds to the antigens and uses thereof in the prevention or treatment of malaria. In particular, compositions are provided comprising fragments of Reticulocyte-binding protein Homologue 5 (PfRH5). In particular, the invention provides fragments of PfRH5 rationally designed on the basis of the PfRH5 crystal structure, wherein said fragments which lack disordered regions, particularly the flexible N-terminal region and/or flexible central linker.Type: GrantFiled: July 30, 2015Date of Patent: August 24, 2021Assignee: OXFORD UNIVERSITY INNOVATION LIMITEDInventors: Simon Draper, Matthew Higgins, Katherine Wright, Alexander Douglas
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Patent number: 10859654Abstract: A method for determining quantitative parameters for dynamic contrast-enhanced MR data includes acquiring a set of contrast-enhanced MR data for a region of interest using a T1-weighted pulse sequence, generating at least one contrast concentration curve based on the set of contrast-enhanced MR data, accessing a comprehensive dictionary of contrast concentration curves and generating a grouped dictionary that has a plurality of groups based on the comprehensive dictionary. Each group includes a plurality of correlated contrast concentration curves and a group representative signal for the group. The method also includes comparing a contrast concentration curve with the group representative signal of each group to select a group, comparing the contrast concentration curve to the plurality of correlated contrast concentration curves in the selected group to identify a set of quantitative parameters for the concentration curve and generating a report including the set of quantitative parameter.Type: GrantFiled: March 12, 2019Date of Patent: December 8, 2020Assignee: CASE WESTERN RESERVE UNIVERSITYInventors: Vikas Gulani, Satyam Ghodasara, Katherine Wright, Nicole Seiberlich, Mark A. Griswold
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Patent number: 10693997Abstract: Embodiments of the present disclosure pertain to network based machine learning generated simulations. In one embodiment, the present disclosure includes a computer implemented method comprising sending first code comprising a programmable calculator from a server system to a client system across a network. A data request is sent to a database, the data request configured to retrieve data from the database comprising a plurality of fields and a target field. The retrieved data is processed using a machine learning algorithm to produce a weight for each field of the plurality of fields and a scoring data structure. The fields and the scoring data structure are sent to the client system across the network. A user selects values for the plurality of fields and the programmable calculator is configured based on the scoring data structure to generate a simulated value for the target field based on the user selected values.Type: GrantFiled: December 15, 2017Date of Patent: June 23, 2020Assignee: SAP SEInventors: Katherine Wright, Sepideh Hashtroodi, Teresa Hsin Yi Su, Flavia Moser, Sajjad Gholami, Zeyu Ni, Geoffrey Neil Peters
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Publication number: 20190353736Abstract: The present application provides a system and method for quantifying perfusion using a dictionary matching approach. In some aspects, the method comprises performing a predetermined pulse sequence using an MRI system to acquire MRI data from the subject after having delivered a dose of a contrast agent to the subject. The method also includes comparing the MRI data to a dictionary to determine perfusion information, and generating, using the perfusion information, a report indicative of perfusion within the subject.Type: ApplicationFiled: May 20, 2019Publication date: November 21, 2019Inventors: Vikas Gulani, Satyam Ghodasara, Katherine Wright, Nicole Seiberlich, Mark A. Griswold
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Publication number: 20190285712Abstract: A method for determining quantitative parameters for dynamic contrast-enhanced MR data includes acquiring a set of contrast-enhanced MR data for a region of interest using a T1-weighted pulse sequence, generating at least one contrast concentration curve based on the set of contrast-enhanced MR data, accessing a comprehensive dictionary of contrast concentration curves and generating a grouped dictionary that has a plurality of groups based on the comprehensive dictionary. Each group includes a plurality of correlated contrast concentration curves and a group representative signal for the group. The method also includes comparing a contrast concentration curve with the group representative signal of each group to select a group, comparing the contrast concentration curve to the plurality of correlated contrast concentration curves in the selected group to identify a set of quantitative parameters for the concentration curve and generating a report including the set of quantitative parameter.Type: ApplicationFiled: March 12, 2019Publication date: September 19, 2019Inventors: Vikas Gulani, Satyam Ghodasara, Katherine Wright, Nicole Seiberlich, Mark A. Griswold
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Publication number: 20190265322Abstract: Apparatus, methods, and other embodiments associated with NMR fingerprinting are described. One example NMR apparatus includes an NMR logic that repetitively and variably samples a (k, t, E) space associated with an object to acquire a set of NMR signals that are associated with different points in the (k, t, E) space. Sampling is performed with t and/or E varying in a non-constant way. Sampling is performed in response to a diffusion-weighted double-echo pulse sequence. Sampling acquires transient-state signals of the double-echo sequence. The NMR apparatus may also include a signal logic that produces an NMR signal evolution from the NMR signals, and a characterization logic that characterizes a resonant species in the object as a result of comparing acquired signals to reference signals.Type: ApplicationFiled: May 6, 2019Publication date: August 29, 2019Inventors: Mark A. Griswold, Vikas Gulani, Dan Ma, Yun Jiang, Katherine Wright
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Patent number: 10379189Abstract: Embodiments associated with combined magnetic resonance angiography and perfusion (MRAP) and nuclear magnetic resonance (NMR) fingerprinting are described. One example apparatus repetitively and variably samples a (k, t, E) space associated with an object to acquire a set of NMR signals that are associated with different points in the (k, t, E) space. Sampling is performed with t and/or E varying in a non-constant way. The apparatus includes a signal logic that produces an NMR signal evolution from the NMR signals and a characterization logic that characterizes a resonant species in the object as a result of comparing acquired signals to reference signals. The apparatus includes an MRAP logic that simultaneously performs MR angiography and produces quantitative perfusion maps. A multi-factor MR bio-imaging panel is produced from a combination of the data provided by the MRAP and NMR fingerprinting. Diagnoses may be made from the multi-factor MR bio-imaging panel.Type: GrantFiled: July 28, 2014Date of Patent: August 13, 2019Assignee: Case Western Reserve UniversityInventors: Vikas Gulani, Mark Griswold, Dan Ma, Katherine Wright, Nicole Seiberlich
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Publication number: 20190191009Abstract: Embodiments of the present disclosure pertain to network based machine learning generated simulations. In one embodiment, the present disclosure includes a computer implemented method comprising sending first code comprising a programmable calculator from a server system to a client system across a network. A data request is sent to a database, the data request configured to retrieve data from the database comprising a plurality of fields and a target field. The retrieved data is processed using a machine learning algorithm to produce a weight for each field of the plurality of fields and a scoring data structure. The fields and the scoring data structure are sent to the client system across the network. A user selects values for the plurality of fields and the programmable calculator is configured based on the scoring data structure to generate a simulated value for the target field based on the user selected values.Type: ApplicationFiled: December 15, 2017Publication date: June 20, 2019Applicant: SAP SEInventors: Katherine Wright, Sepideh Hashtroodi, Teresa Hsin Yi Su, Flavia Moser, Sajjad Gholami, Zeyu Ni, Geoffrey Neil Peters
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Patent number: 10281547Abstract: Apparatus, methods, and other embodiments associated with NMR fingerprinting are described. One example NMR apparatus includes an NMR logic that repetitively and variably samples a (k, t, E) space associated with an object to acquire a set of NMR signals that are associated with different points in the (k, t, E) space. Sampling is performed with t and/or E varying in a non-constant way. Sampling is performed in response to a diffusion-weighted double-echo pulse sequence. Sampling acquires transient-state signals of the double-echo sequence. The NMR apparatus may also include a signal logic that produces an NMR signal evolution from the NMR signals, and a characterization logic that characterizes a resonant species in the object as a result of comparing acquired signals to reference signals.Type: GrantFiled: April 21, 2014Date of Patent: May 7, 2019Assignee: Case Western Reserve UniversityInventors: Mark Griswold, Vikas Gulani, Dan Ma, Yun Jiang, Katherine Wright
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Patent number: 10147314Abstract: Example apparatus and methods provide improved spatial and temporal resolution over conventional magnetic resonance renography (MRR). Example apparatus and methods reconstruct under-sampled three-dimensional (3D) data associated with nuclear magnetic resonance (NMR) signals acquired from a kidney. The data is reconstructed using a 3D through-time non-Cartesian generalized auto-calibrating partially parallel acquisitions (GRAPPA) approach. Example apparatus and methods produce a quantized value for a contrast agent concentration in the kidney from a signal intensity in the data based, at least in part, on a two compartment model of the kidney. The two compartment model includes a plasma compartment and a tubular compartment. The quantized value describes a perfusion parameter for the kidney or a filtration parameter for the kidney.Type: GrantFiled: November 20, 2013Date of Patent: December 4, 2018Assignee: Case Western Reserve UniversityInventors: Vikas Gulani, Katherine Wright, Nicole Seiberlich, Mark Griswold
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Publication number: 20170209558Abstract: There are provided antigens, vectors encoding the antigens, and antibodies and other binding compounds to the antigens and uses thereof in the prevention or treatment of malaria. In particular, compositions are provided comprising fragments of Reticulocyte-binding protein Homologue 5 (PfRH5). In particular, the invention provides fragments of PfRH5 rationally designed on the basis of the PfRH5 crystal structure, wherein said fragments which lack disordered regions, particularly the flexible N-terminal region and/or flexible central linker.Type: ApplicationFiled: July 30, 2015Publication date: July 27, 2017Inventors: Simon Draper, Matthew Higgins, Katherine Wright, Alexander Douglas
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Publication number: 20160025835Abstract: Embodiments associated with combined magnetic resonance angiography and perfusion (MRAP) and nuclear magnetic resonance (NMR) fingerprinting are described. One example apparatus repetitively and variably samples a (k, t, E) space associated with an object to acquire a set of NMR signals that are associated with different points in the (k, t, E) space. Sampling is performed with t and/or E varying in a non-constant way. The apparatus includes a signal logic that produces an NMR signal evolution from the NMR signals and a characterization logic that characterizes a resonant species in the object as a result of comparing acquired signals to reference signals. The apparatus includes an MRAP logic that simultaneously performs MR angiography and produces quantitative perfusion maps. A multi-factor MR bio-imaging panel is produced from a combination of the data provided by the MRAP and NMR fingerprinting. Diagnoses may be made from the multi-factor MR bio-imaging panel.Type: ApplicationFiled: July 28, 2014Publication date: January 28, 2016Inventors: Vikas Gulani, Mark Griswold, Dan Ma, Katherine Wright, Nicole Seiberlich
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Publication number: 20140294734Abstract: Example apparatus and methods provide improved spatial and temporal resolution over conventional magnetic resonance renography (MRR). Example apparatus and methods reconstruct under-sampled three-dimensional (3D) data associated with nuclear magnetic resonance (NMR) signals acquired from a kidney. The data is reconstructed using a 3D through-time non-Cartesian generalized auto-calibrating partially parallel acquisitions (GRAPPA) approach. Example apparatus and methods produce a quantized value for a contrast agent concentration in the kidney from a signal intensity in the data based, at least in part, on a two compartment model of the kidney. The two compartment model includes a plasma compartment and a tubular compartment. The quantized value describes a perfusion parameter for the kidney or a filtration parameter for the kidney.Type: ApplicationFiled: November 20, 2013Publication date: October 2, 2014Inventors: Vikas Gulani, Katherine Wright, Nicole Seiberlich, Mark Griswold