Patents by Inventor Katherine Young

Katherine Young has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230227546
    Abstract: Methods for treating coronavirus disease 2019 (COVID-19), the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, is described. The methods can be used to reduce the severity of outcomes related to COVID-19, such as hospitalization and ventilation. For example, treatment of a subject with a therapeutic agent that neutralizes interleukin 13 (IL-13) can result in reduced risk for mechanical ventilation in the subject. Also described are methods of predicting risk of mechanical ventilation in subjects with COVID-19.
    Type: Application
    Filed: June 17, 2021
    Publication date: July 20, 2023
    Inventors: William A. Petri, JR., Alexandra N. Donlan, Mary Katherine Young, Mayuresh M. Abhyankar, Barbara J. Mann
  • Patent number: 11338730
    Abstract: Lighting assemblies for interiors of vehicles, interior panels for interiors of vehicles, and vehicles are provided herein. In one example, the lighting assembly includes a backing structure having a first backing surface configured to face the interior when the lighting assembly is mounted in the vehicle. A bezel comprises a wall that extends from an outer edge portion to an inner edge portion. The inner edge portion is spaced apart from the first backing surface to define a gap and surrounds an opening that is configured to expose at least a portion of the first backing surface to the interior. A light source is disposed between the backing structure and the bezel and is covered by the wall. The light source is operative to produce light that passes from the light source through the gap onto the first backing surface and is reflected therefrom through the opening to the interior.
    Type: Grant
    Filed: October 8, 2020
    Date of Patent: May 24, 2022
    Assignee: Gulfstream Aerospace Corporation
    Inventors: Joe Guthrie, Katherine Young
  • Patent number: 11242889
    Abstract: An adjustable tie rod includes a first end defined by a screw rod, wherein the screw rod includes a threaded portion, and a second end opposite the first end, wherein an overall length of the adjustable tie rod is defined as a distance between the first end and the second end along a longitudinal axis of the adjustable tie rod. A tie rod shaft extends between and couples the first end and the second end, and a gearbox is fixed with respect to the tie rod shaft. An adjustment actuator is operatively coupled to the gearbox such that selective actuation of the adjustment actuator causes translation of the screw rod along the longitudinal axis and with respect to the gearbox when the first end is prevented from rotating about the longitudinal axis, thereby adjusting the overall length of the adjustable tie rod.
    Type: Grant
    Filed: August 29, 2019
    Date of Patent: February 8, 2022
    Assignee: The Boeing Company
    Inventors: Nathanial C. Cuddy, Samuel Alexander Mori, Jonah Gary Hanson, Allyssa Katherine Young
  • Patent number: 11180504
    Abstract: This invention relates to carbapenem compounds of the following formula: wherein A, Z, X, R1, and R4 are as described herein, as well as stereoisomers, pharmaceutically acceptable salts or N-oxides thereof, which may be useful for the treatment of bacterial infections, particularly drug-resistant bacterial infections, as well as the processes for the preparation of compounds, the pharmaceutical compositions of these compounds and their use in the treatment of bacterial infection.
    Type: Grant
    Filed: March 15, 2017
    Date of Patent: November 23, 2021
    Assignees: ORCHID PHARMA LTD., MERCK SHARP & DOHME CORP.
    Inventors: Gopalan Balasubramanian, Maneesh Paul-Satyaseela, Chidambaram Venkateswaran Srinivasan, Sridhar Ramanathan Iyer, Hariharan Periasamy, Venkatesan Parameswaran, Bharani Thirunavukkarasu, Prabhakar Rao Gunturu, Manjula Devi Deshkumar, Venkateshwarlu Jakkala, Michael Miller, Ravi P. Nargund, Sheo Singh, Shuzhi Dong, Hongwu Wang, Katherine Young
  • Publication number: 20210114515
    Abstract: Lighting assemblies for interiors of vehicles, interior panels for interiors of vehicles, and vehicles are provided herein. In one example, the lighting assembly includes a backing structure having a first backing surface configured to face the interior when the lighting assembly is mounted in the vehicle. A bezel comprises a wall that extends from an outer edge portion to an inner edge portion. The inner edge portion is spaced apart from the first backing surface to define a gap and surrounds an opening that is configured to expose at least a portion of the first backing surface to the interior. A light source is disposed between the backing structure and the bezel and is covered by the wall. The light source is operative to produce light that passes from the light source through the gap onto the first backing surface and is reflected therefrom through the opening to the interior.
    Type: Application
    Filed: October 8, 2020
    Publication date: April 22, 2021
    Applicant: Gulfstream Aerospace Corporation
    Inventors: Joe Guthrie, Katherine Young
  • Patent number: 10947205
    Abstract: The present invention relates to oxazolidinone compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein A, E, and R1 are as defined herein. The present invention also relates to compositions which comprise at least one oxazolidinone compound of the invention. The invention also provides methods for inhibiting growth of mycobacterial cells as well as a method of treating mycobacterial infections by Mycobacterium tuberculosis comprising administering a therapeutically effective amount of an oxazolidinone of the invention and/or a pharmaceutically acceptable salt thereof, or a composition comprising such compound and/or salt.
    Type: Grant
    Filed: April 29, 2019
    Date of Patent: March 16, 2021
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Mihir B. Mandal, David B. Olsen, Jing Su, Lihu Yang, Katherine Young, Takao Suzuki, Lanying You
  • Publication number: 20210061777
    Abstract: The present invention relates to oxazolidinone compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein A, E, and R1 are as defined herein. The present invention also relates to compositions which comprise at least one oxazolidinone compound of the invention. The invention also provides methods for inhibiting growth of mycobacterial cells as well as a method of treating mycobacterial infections by Mycobacterium tuberculosis comprising administering a therapeutically effective amount of an oxazolidinone of the invention and/or a pharmaceutically acceptable salt thereof, or a composition comprising such compound and/or salt.
    Type: Application
    Filed: November 10, 2020
    Publication date: March 4, 2021
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Mihir B. Mandal, David B. Olsen, Jing Su, Lihu Yang, Katherine Young, Takao Suzuki, Lanying You
  • Publication number: 20210062861
    Abstract: An adjustable tie rod includes a first end defined by a screw rod, wherein the screw rod includes a threaded portion, and a second end opposite the first end, wherein an overall length of the adjustable tie rod is defined as a distance between the first end and the second end along a longitudinal axis of the adjustable tie rod. A tie rod shaft extends between and couples the first end and the second end, and a gearbox is fixed with respect to the tie rod shaft. An adjustment actuator is operatively coupled to the gearbox such that selective actuation of the adjustment actuator causes translation of the screw rod along the longitudinal axis and with respect to the gearbox when the first end is prevented from rotating about the longitudinal axis, thereby adjusting the overall length of the adjustable tie rod.
    Type: Application
    Filed: August 29, 2019
    Publication date: March 4, 2021
    Inventors: Nathanial C. Cuddy, Samuel Alexander Mori, Jonah Gary Hanson, Allyssa Katherine Young
  • Publication number: 20210024196
    Abstract: An interior panel for an aircraft, an aircraft including an interior panel, and a method for making an interior panel for an aircraft are provided. In one example, the interior panel includes a support substrate that has a substrate surface. A first trim section is coupled to the support substrate. The first trim section has a first exposed surface that extends to a first edge portion. A second trim section is coupled to the support substrate. The second trim section has a second exposed surface that extends to a second edge portion that is disposed adjacent to the first edge portion. The first edge portion is offset from the second edge portion to define a gap. A light source is substantially covered by the first exposed surface and generates light that passes through the gap and illuminates at least a portion of the second exposed surface.
    Type: Application
    Filed: July 25, 2019
    Publication date: January 28, 2021
    Applicant: Gulfstream Aerospace Corporation
    Inventors: Kevin Sethapun, Katherine Young
  • Publication number: 20200291029
    Abstract: This invention relates to carbapenem compounds, their stereoisomers, pharmaceutically acceptable salts or N-oxides thereof, which may be useful for the treatment of bacterial infections, particularly drug-resistant bacterial infections, as well as the processes for the preparation of compounds, the pharmaceutical compositions of these compounds and their use in the treatment of bacterial infection.
    Type: Application
    Filed: March 15, 2017
    Publication date: September 17, 2020
    Inventors: Gopalan Balasubramanian, Maneesh Paul-Satyaseela, Chidambaram Venkateswaran Srinivasan, Sridhar Ramanathan Iyer, Hariharan Periasamy, Venkatesan Parameswaran, Bharani Thirunavukkarasu, Prabhakar Rao Gunturu, Manjula Devi Deshkumar, Venkateshwarlu Jakkala, Michael Miller, Ravi P. Nargund, Sheo Singh, Shuzhi Dong, Hongwu Wang, Katherine Young
  • Patent number: 10544130
    Abstract: The present invention relates to metallo-?-lactamase inhibitor compounds of Formula I: and pharmaceutically acceptable salts thereof, wherein Z, RA, X1, X2 and R1 are as defined herein. The present invention also relates to compositions which comprise a metallo-?-lactamase inhibitor compound of the invention or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, optionally in combination with a beta lactam antibiotic and/or a beta-lactamase inhibitor. The invention further relates to methods for treating a bacterial infection comprising administering to a patient a therapeutically effective amount of a compound of the invention, in combination with a therapeutically effective amount of one or more ?-lactam antibiotics and optionally in combination with one or more beta-lactamase inhibitor compounds. The compounds of the invention are useful in the methods described herein for overcoming antibiotic resistance.
    Type: Grant
    Filed: January 10, 2019
    Date of Patent: January 28, 2020
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Frank Bennett, Jinlong Jiang, Alexander Pasternak, Shuzhi Dong, Xin Gu, Jack D. Scott, Haiqun Tang, Zhiqiang Zhao, Yuhua Huang, Dexi Yang, Katherine Young, Li Xiao, Zhibo Zhang, Jianmin Fu
  • Publication number: 20190248753
    Abstract: The present invention relates to oxazolidinone compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein A, E, and R1 are as defined herein. The present invention also relates to compositions which comprise at least one oxazolidinone compound of the invention. The invention also provides methods for inhibiting growth of mycobacterial cells as well as a method of treating mycobacterial infections by Mycobacterium tuberculosis comprising administering a therapeutically effective amount of an oxazolidinone of the invention and/or a pharmaceutically acceptable salt thereof, or a composition comprising such compound and/or salt.
    Type: Application
    Filed: April 29, 2019
    Publication date: August 15, 2019
    Inventors: Mihir B. Mandal, David B. Olsen, Jing Su, Lihu Yang, Katherine Young, Takao Suzuki, Lanying You
  • Publication number: 20190144432
    Abstract: The present invention relates to metallo-?-lactamase inhibitor compounds of Formula I: and pharmaceutically acceptable salts thereof, wherein Z, RA, X1, X2 and R1 are as defined herein. The present invention also relates to compositions which comprise a metallo-?-lactamase inhibitor compound of the invention or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, optionally in combination with a beta lactam antibiotic and/or a beta-lactamase inhibitor. The invention further relates to methods for treating a bacterial infection comprising administering to a patient a therapeutically effective amount of a compound of the invention, in combination with a therapeutically effective amount of one or more ?-lactam antibiotics and optionally in combination with one or more beta-lactamase inhibitor compounds. The compounds of the invention are useful in the methods described herein for overcoming antibiotic resistance.
    Type: Application
    Filed: January 10, 2019
    Publication date: May 16, 2019
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Frank Bennett, Jinlong Jiang, Alexander Pasternak, Shuzhi Dong, Xin Gu, Jack D. Scott, Haiqun Tang, Zhiqiang Zhao, Yuhua Huang, Dexi Yang, Katherine Young, Li Xiao, Zhibo Zhang, Jianmin Fu
  • Patent number: 10227331
    Abstract: The present invention relates to metallo-?-lactamase inhibitor compounds of Formula I: (I) and pharmaceutically acceptable salts thereof, wherein Z, RA, X1, X2 and RB are as defined herein. The present invention also relates to compositions which comprise a metallo-?-lactamase inhibitor compound of the invention or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, optionally in combination with a beta lactam antibiotic and/or a beta-lactamase inhibitor. The invention further relates to methods for treating a bacterial infection comprising administering to a patient a therapeutically effective amount of a compound of the invention, in combination with a therapeutically effective amount of one or more ?-lactam antibiotics and optionally in combination with one or more beta-lactamase inhibitor compounds. The compounds of the invention are useful in the methods described herein for overcoming antibiotic resistance.
    Type: Grant
    Filed: June 24, 2016
    Date of Patent: March 12, 2019
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Frank Bennett, Jinlong Jiang, Alexander Pasternak, Shuzhi Dong, Xin Gu, Jack D. Scott, Haiqun Tang, Zhiqiang Zhao, Yuhua Huang, David Hunter, Dexi Yang, Katherine Young, Li Xiao, Zhibo Zhang, Jianmin Fu, Yunfeng Bai, Zhixiang Zheng, Xu Zhang
  • Patent number: 10221163
    Abstract: The present invention relates to metallo-beta-lactamase inhibitor compounds of Formula I: and pharmaceutically acceptable salts thereof, wherein Z, RA, X1, X2 and R1 are as defined herein. The present invention also relates to compositions which comprise a metallo-beta-lactamase inhibitor compound of the invention or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, optionally in combination with a beta-lactam antibiotic and/or a beta-lactamase inhibitor. The invention further relates to methods for treating a bacterial infection comprising administering to a patient a therapeutically effective amount of a compound of the invention, in combination with a therapeutically effective amount of one or more ?-lactam antibiotics and optionally in combination with one or more beta-lactamase inhibitor compounds. The compounds of the invention are useful in the methods described herein for overcoming antibiotic resistance.
    Type: Grant
    Filed: June 24, 2016
    Date of Patent: March 5, 2019
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Frank Bennett, Jinlong Jiang, Alexander Pasternak, Shuzhi Dong, Xin Gu, Jack D. Scott, Haiqun Tang, Zhiqiang Zhao, Yuhua Huang, Dexi Yang, Katherine Young, Li Xiao, Zhibo Zhang, Jianmin Fu
  • Patent number: 10144741
    Abstract: The present invention relates to novel nargenicin related compounds which can inhibit DnaE and have antibacterial, particularly antimycobacterial activity against Mycobacterium tuberculosis. The present invention also relates to method for inhibiting growth of mycobacterial cells as well as a method of treating mycobacterial infections by Mycobacterium tuberculosis by administering an antimycobacterially effective amount of nargenicin or a nargenicin-related compound and/or their pharmaceutically acceptable salts.
    Type: Grant
    Filed: March 2, 2018
    Date of Patent: December 4, 2018
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Katherine Young, David B. Olsen, Sheo B. Singh, Jing Su, Robert R. Wilkening, James M. Apgar, Dongfang Meng, Dann Parker, Mihir Mandal, Lihu Yang, Ronald E. Painter, Qun Dang, Takao Suzuki
  • Publication number: 20180290987
    Abstract: The present invention relates to oxazolidinone compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein A, E, and R1 are as defined herein. The present invention also relates to compositions which comprise at least one oxazolidinone compound of the invention. The invention also provides methods for inhibiting growth of mycobacterial cells as well as a method of treating mycobacterial infections by Mycobacterium tuberculosis comprising administering a therapeutically effective amount of an oxazolidinone of the invention and/or a pharmaceutically acceptable salt thereof, or a composition comprising such compound and/or salt.
    Type: Application
    Filed: October 17, 2016
    Publication date: October 11, 2018
    Inventors: Mihir B. Mandal, David B. Olsen, Jing Su, Lihu Yang, Katherine Young, Takao Suzuki, Lanying You
  • Patent number: D906002
    Type: Grant
    Filed: October 18, 2019
    Date of Patent: December 29, 2020
    Assignee: Gulfstream Aerospace Corporation
    Inventors: Timothy O'Hara, Kevin Sethapun, Salvador Gonzalez, Katherine Young
  • Patent number: D976800
    Type: Grant
    Filed: July 25, 2019
    Date of Patent: January 31, 2023
    Assignee: Gulfstream Aerospace Corporation
    Inventors: Kevin Sethapun, Katherine Young
  • Patent number: D1011570
    Type: Grant
    Filed: October 17, 2019
    Date of Patent: January 16, 2024
    Inventors: Joe Guthrie, Katherine Young