Patents by Inventor Kathia Lemdani

Kathia Lemdani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunomodulation after locoregional anti-tumoral treatment
    Patent number: 11723956
    Abstract: The present invention concerns a thermosensitive polymeric hydrogel comprising at least one thermosensitive copolymer, one aqueous solution, and a mucoadhesive excipient, wherein said thermosensitive polymeric hydrogel further comprises at least one immunostimulatory adjuvant and/or at least one cytokine and/or at least one chemokine and/or atleast one heat shockprotein. Another object of the invention is a thermosensitive polymeric hydrogel according to the invention for use in the treatment of tumors or metastasis in a subject having a cancer, preferably a metastatic cancer.
    Type: Grant
    Filed: August 31, 2017
    Date of Patent: August 15, 2023
    Assignees: Institut National de la Sante et de la Recherche Medicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Université de Paris, Assistance Publique—Hopitaux de Paris, Ecole Nationale Superieure de Chimie de Paris, Universite de Versailles—St. Quentin en Yvelines
    Inventors: Robert Malafosse, Nathalie Mignet, Vincent Boudy, Johanne Seguin, Kathia Lemdani, Claude Capron
  • Process for determining the infiltration of biological cells in a biological object of interest
    Patent number: 11263781
    Abstract: The invention relates to a process for determining an infiltration profile of biological cells of interest in a biological object of interest from a digital histopathological image of biological tissues, a histological stain having previously been applied to the biological tissues, comprising generating a biological cell detection image, pixels associated with the histological stain on the histopathological image being of a predetermined color on said image, determining a distance map comprising distance iso-curves to the boundary of the biological object, and, from the distance map, calculating a curve representative of the surface density of biological cells of interest as a function of distance to the boundary, by counting, for each boundary distance value, pixels that are both of the predetermined color on the detection image and located between the iso-curve associated with said distance value and the consecutive iso-curve.
    Type: Grant
    Filed: June 4, 2019
    Date of Patent: March 1, 2022
    Inventors: Kathia Lemdani, Johanne Seguin, Armand Tiede Djiro, Jean-Francois Emile, Camille Kurtz, Nicolas Lomenie
  • Process For Determining The Infiltration Of Biological Cells In A Biological Object Of Interest
    Publication number: 20190392612
    Abstract: The invention relates to a process for determining an infiltration profile of biological cells of interest in a biological object of interest from a digital histopathological image of biological tissues, a histological stain having previously been applied to the biological tissues, comprising generating a biological cell detection image, pixels associated with the histological stain on the histopathological image being of a predetermined color on said image, determining a distance map comprising distance iso-curves to the boundary of the biological object, and, from the distance map, calculating a curve representative of the surface density of biological cells of interest as a function of distance to the boundary, by counting, for each boundary distance value, pixels that are both of the predetermined color on the detection image and located between the iso-curve associated with said distance value and the consecutive iso-curve.
    Type: Application
    Filed: June 4, 2019
    Publication date: December 26, 2019
    Applicants: Centre National de la Recherche Scientifique (CNRS), Universite Paris Descartes, Ecole Nationale Superieure de Chimie de Paris, Assistance Publique-Hopitaux de Paris, Universite De Versailles-St Quentin En Yvelines, Institut National de la Sante et de la Recherche Medicale (INSERM)
    Inventors: Kathia Lemdani, Johanne Seguin, Armand Tiede Djiro, Jean-Francois Emile, Camille Kurtz, Nicolas Lomenie
  • IMMUNOMODULATION AFTER LOCOREGIONAL ANTI-TUMORAL TREAMENT
    Publication number: 20190201492
    Abstract: The present invention concerns a thermosensitive polymeric hydrogel comprising at least one thermosensitive copolymer, one aqueous solution, and a mucoadhesive excipient, wherein said thermosensitive polymeric hydrogel further comprises at least one immunostimulatory adjuvant and/or at least one cytokine and/or at least one chemokine and/or atleast one heat shockprotein. Another object of the invention is a thermosensitive polymeric hydrogel according to the invention for use in the treatment of tumors or metastasis in a subject having a cancer, preferably a metastatic cancer.
    Type: Application
    Filed: August 31, 2017
    Publication date: July 4, 2019
    Applicants: Institut National de la Sante et de la Recherche Medicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Universite Paris Descartes, Assistance Publique - Hopitaux de Paris, Ecole Nationale Superieure de Chimie de Paris, Universite de Versailles-St Quentin en Yvelines
    Inventors: Robert Malafosse, Nathalie Mignet, Vincent Boudy, Johanne Seguin, Kathia Lemdani, Claude Capron