Patents by Inventor Kathleen A. Donovan

Kathleen A. Donovan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IL1-?: a new target for myeloma therapy
    Patent number: 7820167
    Abstract: Diagnostic methods for the detection of multiple myeloma (MM) and the identification of high-risk patients with multiple myeloma-related plasma proliferative disorders, such as MGUS or SMM, likely to progress to active MM are described. The diagnosis is based on the determination of concentrations of bioactive IL-1? produced by the bone marrow plasma cells of these patients. Also described are therapeutic methods for the treatment of MM and for the chemoprevention of the progression from disorders such as MGUS and SMM to active MM, involving the administration of inhibitors of IL-1?.
    Type: Grant
    Filed: January 26, 2005
    Date of Patent: October 26, 2010
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Kathleen A. Donovan, John A. Lust
  • IL1-beta: a new target for myeloma therapy
    Publication number: 20050164312
    Abstract: Diagnostic methods for the detection of multiple myeloma (MM) and the identification of high-risk patients with multiple myeloma-related plasma proliferative disorders, such as MGUS or SMM, likely to progress to active MM are described; The diagnosis is based on the determination of concentrations of bioactive IL-1? produced by the bone marrow plasma cells of these patients. Also described are therapeutic methods for the treatment of MM and for the chemoprevention of the progression from disorders such as MGUS and SMM to active MM, involving the administration of inhibitors of IL-1?.
    Type: Application
    Filed: January 26, 2005
    Publication date: July 28, 2005
    Inventors: Kathleen Donovan, John Lust
  • IL1-?: a new target for myeloma therapy
    Patent number: 6864047
    Abstract: Diagnostic methods for the detection of multiple myeloma (MM) and the identification of high-risk patients with multiple myeloma-related plasma proliferative disorders, such as MGUS or SMM, likely to progress to active MM are described. The diagnosis is based on the determination of concentrations of bioactive IL-1? produced by the bone marrow plasma cells of these patients. Also described are therapeutic methods for the treatment of MM and for the chemoprevention of the progression from disorders such as MGUS and SMM to active MM, involving the administration of inhibitors of IL-1?.
    Type: Grant
    Filed: March 29, 2001
    Date of Patent: March 8, 2005
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Kathleen A. Donovan, John A. Lust
  • Use of genetically engineered antibodies to treat multiple myeloma
    Publication number: 20040141982
    Abstract: A fusion polypeptide comprising an antibody or a fragment thereof is provided. The fusion polypeptide is useful in a therapeutic composition to treat multiple myeloma.
    Type: Application
    Filed: November 7, 2003
    Publication date: July 22, 2004
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: John A. Lust, Kathleen A. Donovan
  • IL1-beta: a new target for myeloma therapy
    Publication number: 20020176857
    Abstract: Diagnostic methods for the detection of multiple myeloma (MM) and the identification of high-risk patients with multiple myeloma-related plasma proliferative disorders, such as MGUS or SMM, likely to progress to active MM are described. The diagnosis is based on the determination of concentrations of bioactive IL-1&bgr; produced by the bone marrow plasma cells of these patients. Also described are therapeutic methods for the treatment of MM and for the chemoprevention of the progression from disorders such as MGUS and SMM to active MM, involving the administration of inhibitors of IL-1&bgr;.
    Type: Application
    Filed: March 29, 2001
    Publication date: November 28, 2002
    Inventors: Kathleen A. Donovan, John A. Lust
  • Use of genetically engineered antibodies to treat multiple myeloma
    Publication number: 20010031261
    Abstract: A fusion polypeptide comprising an antibody or a fragment thereof is provided. The fusion polypeptide is useful in a therapeutic composition to treat multiple myeloma.
    Type: Application
    Filed: December 5, 2000
    Publication date: October 18, 2001
    Inventors: John A. Lust, Kathleen A. Donovan