Abstract: The invention relates to thiazole derivatives corresponding to the general formula: ##STR1## in which: - R.sub.1 and R.sub.2 each independently represent hydrogen; a C.sub.1 -C.sub.4 alkyl group; a phenyl group or a phenyl group monosubstituted or polysubstituted by a halogen atom, a C.sub.1 -C.sub.4 alkyl group, a C.sub.1 -C.sub.4 alkoxy, nitro or hydroxyl group; or one of the groups R.sub.1 and R.sub.2 denotes hydrogen and the other represents a naphthyl group; a benzyl group; an .alpha.,.alpha.-dimethyl-benzyl group; a cyclohexyl group; a biphenyl group; a thienyl group or an adamantyl group; or alternatively R.sub.1 and R.sub.2, taken together, represent a group; ##STR2## in which the phenyl group is bonded to the 4-position of the thiazole and the group (CH.sub.2).sub.m to the 5-position, m represents an integer equal to 2 or 3 and R.sub.5 denotes hydrogen or a nitro group, R.sub.3 is H or an alkyl group and R.sub.4 is notably an alkyl substituted by an amino group, a pyrrolidino, or a pydridino group.

Abstract: The invention relates to thiazole derivatives corresponding to the general formula: ##STR1## in which: R.sub.1 and R.sub.2 each independently represent hydrogen; a C.sub.1 -C.sub.4 alkyl group; a phenyl group or a phenyl group monosubstituted or polysubstituted by a halogen atom, a C.sub.1 -C.sub.4 alkyl group, a C.sub.1 -C.sub.4 alkoxy, nitro or hydroxyl group; or one of the groups R.sub.1 and R.sub.2 denotes hydrogen and the other represents a naphthyl group; a benzyl group; an .alpha.,.alpha.-dimethyl-benzyl group; a cyclohexyl group; a biphenyl group; a thienyl group of an adamantyl group; or alternatively R.sub.1 and R.sub.2, taken together, represent a group; ##STR2## in which the phenyl group is bonded to the 4-position of the thiazole and the group (CH.sub.2).sub.m to the 5-position, m represents an integer equal to 2 or 3 and R.sub.5 denotes hydrogen or a nitro group, R.sub.3 is H or an alkyl group and R.sub.4 is notably an alkyl substituted by an amino group, a pyrrolidino, or a pyridino group.

Abstract: The invention relates to novel tricyclic derivatives which are agonists of cholinergic receptors and to drugs containing them.These derivatives have the following formula: ##STR1## in which: X represents a group (CH.sub.2).sub.n, n representing an integer equal to 2, 3 or 4, or alternatively a vinylene group or a methylvinylene group;R.sub.1 and R.sub.2, considered independently, represent hydrogen or a substituent occupying one of the free positions of the benzene ring and selected from the group comprising halogens, a lower alkyl group, a lower alkoxy group, a hydroxyl group, a thiol group, a nitro group and an optionally substituted amino group;Y represents oxygen, sulfur or a group --NH--; andR.sub.3 is an amino groupApplication: agonists of the cholinergic receptors.

Abstract: The invention relates to the pyridazine derivatives of the formula: ##STR1## in which R.sub.1 is H, a substituted or unsubstituted phenyl group, a naphthyl group, a cyclohexyl group, a thien-2-yl group, a thien-3-yl group or an indol-3-yl group, R.sub.2 is H or an alkyl or phenyl group, R.sub.3 is H, an alkyl, or phenyl group in formula Ib and a cyano group in formula Ia, and Alk is (CH.sub.2).sub.n where n is 2, 3 or 4, or --CH.sub.2 --C.ident.C--, and X.sup.- is halide, a process for the preparation of the said products and their application as medicaments.

Abstract: The present invention relates to derivatives of 4-methyl 6-phenyl pyridazine of formula: ##STR1## in which R is OH or H, R.sub.1 is H or ##STR2## n being 0 or 1, X being H, Y being H or alkyl or X and Y forms an ethylene or oxoethylene group;it also relates to a process for preparing the products of formula (I) and to drugs containing at least one product of formula (I).

Abstract: The invention relates to pyridazine derivatives substituted in the 4-position by a cyano group. It also relates to a process for the preparation of these products and their application as medicaments.

Abstract: The present invention relates to the compounds of formula ##STR1## in which X.sub.1 represents N or ##STR2## X.sub.2 represents N or ##STR3## provided that X.sub.1 and X.sub.2 are different from each other; R.sub.1 and R.sub.2 being --(CH.sub.2).sub.n OH wherein n is 1 to 4 or ##STR4## represents a saturated heterocycle with 5 or 6 groupings containing one nitrogen atom as heteroatom, substituted in 3 or 4 position for example by (CH.sub.2).sub.m OR.sub.6 where R.sub.6 is H or an acyl radical or an amido radical; to a process for preparing said compounds; and to the drugs containing said compounds active in particular on the central nervous system.

Abstract: The invention relates to compounds with a nitrogen-containing heterocyclic nucleus, of the general formula: ##STR1## in which: Ar represents a group ##STR2## or a naphthyl group optionally substituted by a halogen, A represents a heterocyclic nucleus chosen from the group consisting of the pyridine, pyrimidine and triazine nuclei, andX and Y, taken separately, denote a hydrogen atom in one case and a group OR.sub.3 (hydroxyl, carbamate or ester) in the other.The invention also relates to a process for the preparation of these compounds and their application as drugs acting on the central nervous system.

Abstract: The invention relates to pyrrolidinones of the general formula: ##STR1## in which: R.sub.1 represents hydrogen or alkylR.sub.2 represents alkyl, phenyl or trimethylsilyl.R.sub.3 represents 2-thienyl or a phenyl possibly substituted once or twice with halogen, methyl, methoxy or a trifluoromethyl group. It relates also to a process for the production of these compounds and to the pharmaceutical compositions containing them.

Abstract: The present invention relates to derivatives of 4-methyl 6-phenyl pyridazine of formula: ##STR1## in which R is OH or H, R.sub.1 is H or ##STR2## n being 0 or 1, X being H, Y being H or alkyl or X and Y forms an ethylene or oxoethylene group;it also relates to a process for preparing the products of formula (I) and to drugs containing at least one product of formula (I).

Abstract: This invention relates to pyridazine derivatives substituted in the 4-position by a cyano group having psychotropic activity. It also relates to a process for the preparation of these products and their application as medicaments.

Abstract: The present invention relates to a process for preparing 2-(1-piperazinyl) pyrimidines of formula: ##STR1## in which one of the groups T and Q represents hydrogen, a hydroxyl or lower alkanoyloxy group, and the other represents hydrogen; and X represents:a group --CO--R.sub.1a group ##STR2## an alkylene-COOY group an alkylene-CO--W group,according to which a 2-(1-piperazinyl) pyrimidine of formula: ##STR3## is reacted with a compound of formula AX in which A is selected from an atom of halogen and an activator group of the carboxylic function of the radical X.

Abstract: The present invention relates to new derivatives of formula: ##STR1## in which: R.sub.3 denotes a halogen, preferably chlorine, or a nitro group,R.sub.4 represents hydrogen or a lower alkyl group having from 1 to 4 atoms of carbon,R.sub.5 represents an atom of halogen, preferably chlorine or fluorine.It also relates to a process for preparing products of formula (II) and to the drugs containing at least one product of formula (II).

Abstract: The present invention relates to aminated derivatives of pyridazine of formula: ##STR1## in which: . R.sub.1 designates a 2-thienyl, 3-thienyl or cyclohexyl group;R.sub.2 represents a lower alkyl group (1 to 4 atoms of carbon), or an atom of hydrogen as well as the salts of said derivatives with the acids; which compounds effect the central nervous system and may be used in human medicine to treat depression. It also relates to a process for preparing said derivatives and the drugs containing them.

Abstract: The present invention relates to derivatives of 4-methyl 6-phenyl pyridazine of formula: ##STR1## in which R is OH or H,R.sub.1 is ##STR2## n being 0 or 1, X and Y forms an ethylene or oxoethylene group;it also relates to a process for preparing the products of formula (I) and to drugs containing at least one product of formula (I).

Abstract: The present invention relates to amino derivatives of pyridazine of general formula: ##STR1## in which one of the substituents R.sub.1, R.sub.2 or R.sub.3 represents a phenyl or hydroxyphenyl group, while the other two represent hydrogen or an alkyl group with C.sub.1 -C.sub.4 ;A represents a linear or branched alkylene group having 2 to 5 carbon atoms;X represents hydrogen or an alkyl group with C.sub.1 -C.sub.4, as well as the salts of said derivatives with the pharmaceutically acceptable acids, and also relates to a process for preparing the products of formula (I) and to drugs containing a product of formula (I).

Abstract: The present invention relates to novel derivatives of 4-phenyl quinazoline of general formula: ##STR1## in which R.sub.2 is H or halogen or R.sub.1 is a hydroxyamino derivative of type ##STR2## in which at least R.sub.3 or R.sub.4 comprises an OH group or ##STR3## in which R.sub.5 comprises an OH group or ##STR4## it also relates to the drugs which may be used as minor tranquilizers, hypnotics and antiepileptics containing a product of formula (I).