Patents by Inventor KATHLEEN D.A. LOS

KATHLEEN D.A. LOS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11278494
    Abstract: Embodiments of the present application relate to commercial manufacturing processes for making bupivacaine multivesicular liposomes (MVLs) using independently operating dual tangential flow filtration modules.
    Type: Grant
    Filed: January 22, 2021
    Date of Patent: March 22, 2022
    Assignee: Pacira Pharmaceuticals, Inc.
    Inventors: Jeffrey S. Hall, David J. Turnbull, John J. Grigsby, Jr., Soroush M. Ardekani, Paige N. Davis, Louie D. Garcia, Stephanie M. Kurz, Kathleen D. A. Los
  • Patent number: 11185506
    Abstract: Embodiments of the present application relate to commercial manufacturing processes for making bupivacaine multivesicular liposomes (MVLs) using independently operating dual tangential flow filtration modules.
    Type: Grant
    Filed: May 13, 2021
    Date of Patent: November 30, 2021
    Assignee: Pacira Pharmaceuticals, Inc.
    Inventors: Jeffrey S. Hall, David J. Turnbull, John J. Grigsby, Jr., Soroush M. Ardekani, Paige N. Davis, Louie D. Garcia, Stephanie M. Kurz, Kathleen D. A. Los
  • Patent number: 11179336
    Abstract: Embodiments of the present application relate to commercial manufacturing processes for making bupivacaine multivesicular liposomes (MVLs) using independently operating dual tangential flow filtration modules.
    Type: Grant
    Filed: May 13, 2021
    Date of Patent: November 23, 2021
    Assignee: Pacira Pharmaceuticals, Inc.
    Inventors: Jeffrey S. Hall, David J. Turnbull, John J. Grigsby, Jr., Soroush M. Ardekani, Paige N. Davis, Louie D. Garcia, Stephanie M. Kurz, Kathleen D. A. Los
  • Patent number: 11033495
    Abstract: Embodiments of the present application relate to commercial manufacturing processes for making bupivacaine multivesicular liposomes (MVLs) using independently operating dual tangential flow filtration modules.
    Type: Grant
    Filed: January 22, 2021
    Date of Patent: June 15, 2021
    Assignee: Pacira Pharmaceuticals, Inc.
    Inventors: Jeffrey S. Hall, David J. Turnbull, John J. Grigsby, Jr., Soroush M. Ardekani, Paige N. Davis, Louie D. Garcia, Stephanie M. Kurz, Kathleen D. A. Los
  • Patent number: 10398648
    Abstract: The present invention generally relates to the field of pharmaceutical sciences. More specifically, the present invention includes apparatus and devices for the preparation of pharmaceutical formulations containing large diameter synthetic membrane vesicles, such as multivesicular liposomes, methods for preparing such formulations, and the use of specific formulations for therapeutic treatment of subjects in need thereof. Formation and use of the pharmaceutical formulations containing large diameter synthetic membrane vesicles produced by using the apparatus and devices for therapeutic treatment of subjects in need thereof is also contemplated.
    Type: Grant
    Filed: August 14, 2017
    Date of Patent: September 3, 2019
    Assignee: Pacira Pharmaceuticals, Inc.
    Inventors: Ernest George Schutt, Ronald Warren McGuire, Peter Andrew Walters, Kathleen D. A. Los
  • Patent number: 10045941
    Abstract: The present invention generally relates to the field of pharmaceutical sciences. More specifically, the present invention includes apparatus and devices for the preparation of pharmaceutical formulations containing large diameter synthetic membrane vesicles, such as multivesicular liposomes, methods for preparing such formulations, and the use of specific formulations for therapeutic treatment of subjects in need thereof. Formation and use of the pharmaceutical formulations containing large diameter synthetic membrane vesicles produced by using the apparatus and devices for therapeutic treatment of subjects in need thereof is also contemplated.
    Type: Grant
    Filed: March 6, 2013
    Date of Patent: August 14, 2018
    Assignee: Pacira Pharmaceuticals, Inc.
    Inventors: Ernest George Schutt, Ronald Warren McGuire, Peter Andrew Walters, Kathleen D. A. Los
  • Publication number: 20180092847
    Abstract: The present invention generally relates to the field of pharmaceutical sciences. More specifically, the present invention includes apparatus and devices for the preparation of pharmaceutical formulations containing large diameter synthetic membrane vesicles, such as multivesicular liposomes, methods for preparing such formulations, and the use of specific formulations for therapeutic treatment of subjects in need thereof. Formation and use of the pharmaceutical formulations containing large diameter synthetic membrane vesicles produced by using the apparatus and devices for therapeutic treatment of subjects in need thereof is also contemplated.
    Type: Application
    Filed: August 14, 2017
    Publication date: April 5, 2018
    Inventors: Ernest George Schutt, Ronald Warren McGuire, Peter Andrew Walters, Kathleen D.A. Los
  • Patent number: 9808424
    Abstract: The present invention generally relates to the field of pharmaceutical sciences. More specifically, the present invention includes apparatus and devices for the preparation of pharmaceutical formulations containing large diameter synthetic membrane vesicles, such as multivesicular liposomes, methods for preparing such formulations, and the use of specific formulations for therapeutic treatment of subjects in need thereof. Formation and use of the pharmaceutical formulations containing large diameter synthetic membrane vesicles produced by using the apparatus and devices for therapeutic treatment of subjects in need thereof is also contemplated.
    Type: Grant
    Filed: March 8, 2013
    Date of Patent: November 7, 2017
    Assignee: Pacira Pharmaceuticals, Inc.
    Inventors: Ernest George Schutt, Ronald Warren McGuire, Peter Andrew Walters, Kathleen D. A. Los
  • Patent number: 9757336
    Abstract: The present invention generally relates to the field of pharmaceutical sciences. More specifically, the present invention includes apparatus and devices for the preparation of pharmaceutical formulations containing large diameter synthetic membrane vesicles, such as multivesicular liposomes, methods for preparing such formulations, and the use of specific formulations for therapeutic treatment of subjects in need thereof. Formation and use of the pharmaceutical formulations containing large diameter synthetic membrane vesicles produced by using the apparatus and devices for therapeutic treatment of subjects in need thereof is also contemplated.
    Type: Grant
    Filed: March 6, 2013
    Date of Patent: September 12, 2017
    Assignee: Pacira Pharmaceuticals, Inc.
    Inventors: Ernest George Schutt, Ronald Warren McGuire, Peter Andrew Walters, Kathleen D. A. Los
  • Patent number: 9737482
    Abstract: The present invention generally relates to the field of pharmaceutical sciences. More specifically, the present invention includes apparatus and devices for the preparation of pharmaceutical formulations containing large diameter synthetic membrane vesicles, such as multivesicular liposomes, methods for preparing such formulations, and the use of specific formulations for therapeutic treatment of subjects in need thereof. Formation and use of the pharmaceutical formulations containing large diameter synthetic membrane vesicles produced by using the apparatus and devices for therapeutic treatment of subjects in need thereof is also contemplated.
    Type: Grant
    Filed: March 6, 2013
    Date of Patent: August 22, 2017
    Assignee: Pacira Pharmaceuticals, Inc.
    Inventors: Ernest George Schutt, Ronald Warren McGuire, Peter Andrew Walters, Kathleen D. A. Los
  • Patent number: 9737483
    Abstract: The present invention generally relates to the field of pharmaceutical sciences. More specifically, the present invention includes apparatus and devices for the preparation of pharmaceutical formulations containing large diameter synthetic membrane vesicles, such as multivesicular liposomes, methods for preparing such formulations, and the use of specific formulations for therapeutic treatment of subjects in need thereof. Formation and use of the pharmaceutical formulations containing large diameter synthetic membrane vesicles produced by using the apparatus and devices for therapeutic treatment of subjects in need thereof is also contemplated.
    Type: Grant
    Filed: March 6, 2013
    Date of Patent: August 22, 2017
    Assignee: Pacira Pharmaceuticals, Inc.
    Inventors: Ernest George Schutt, Ronald Warren McGuire, Peter Andrew Walters, Kathleen D. A. Los
  • Patent number: 9730892
    Abstract: The present invention generally relates to the field of pharmaceutical sciences. More specifically, the present invention includes apparatus and devices for the preparation of pharmaceutical formulations containing large diameter synthetic membrane vesicles, such as multivesicular liposomes, methods for preparing such formulations, and the use of specific formulations for therapeutic treatment of subjects in need thereof. Formation and use of the pharmaceutical formulations containing large diameter synthetic membrane vesicles produced by using the apparatus and devices for therapeutic treatment of subjects in need thereof is also contemplated.
    Type: Grant
    Filed: August 26, 2016
    Date of Patent: August 15, 2017
    Assignee: Pacira Pharmaceuticals, Inc.
    Inventors: Ernest George Schutt, Ronald Warren McGuire, Peter Andrew Walters, Kathleen D. A. Los
  • Patent number: 9724302
    Abstract: The present invention generally relates to the field of pharmaceutical sciences. More specifically, the present invention includes apparatus and devices for the preparation of pharmaceutical formulations containing large diameter synthetic membrane vesicles, such as multivesicular liposomes, methods for preparing such formulations, and the use of specific formulations for therapeutic treatment of subjects in need thereof. Formation and use of the pharmaceutical formulations containing large diameter synthetic membrane vesicles produced by using the apparatus and devices for therapeutic treatment of subjects in need thereof is also contemplated.
    Type: Grant
    Filed: March 5, 2013
    Date of Patent: August 8, 2017
    Assignee: Pacira Pharmaceuticals, Inc.
    Inventors: Ernest George Schutt, Ronald Warren McGuire, Peter Andrew Walters, Kathleen D. A. Los
  • Publication number: 20160361260
    Abstract: The present invention generally relates to the field of pharmaceutical sciences. More specifically, the present invention includes apparatus and devices for the preparation of pharmaceutical formulations containing large diameter synthetic membrane vesicles, such as multivesicular liposomes, methods for preparing such formulations, and the use of specific formulations for therapeutic treatment of subjects in need thereof. Formation and use of the pharmaceutical formulations containing large diameter synthetic membrane vesicles produced by using the apparatus and devices for therapeutic treatment of subjects in need thereof is also contemplated.
    Type: Application
    Filed: August 26, 2016
    Publication date: December 15, 2016
    Inventors: Ernest George Schutt, Ronald Warren McGuire, Peter Andrew Walters, Kathleen D.A. Los
  • Publication number: 20160206580
    Abstract: Some embodiments of the present application are related to multivesicular liposome formulations comprising tranexamic acid (TXA) for the purpose of minimizing the side effects of unencapsulated tranexamic while maintaining or improving efficacy and lengthening the duration of the effect. Methods of making and administering the tranexamic acid encapsulated multivesicular liposome formulations and their use as medicaments are also provided.
    Type: Application
    Filed: January 20, 2016
    Publication date: July 21, 2016
    Inventors: Kathleen D.A. Los, Louie Daniel Garcia, Stephanie Kurz, Vladimir Kharitonov
  • Publication number: 20110250264
    Abstract: The present invention generally relates to the field of pharmaceutical sciences. More specifically, the present invention includes apparatus and devices for the preparation of pharmaceutical formulations containing large diameter synthetic membrane vesicles, such as multivesicular liposomes, methods for preparing such formulations, and the use of specific formulations for therapeutic treatment of subjects in need thereof. Formation and use of the pharmaceutical formulations containing large diameter synthetic membrane vesicles produced by using the apparatus and devices for therapeutic treatment of subjects in need thereof is also contemplated.
    Type: Application
    Filed: April 8, 2011
    Publication date: October 13, 2011
    Applicant: PACIRA PHARMACEUTICALS, INC.
    Inventors: ERNEST GEORGE SCHUTT, RONALD WARREN MCGUIRE, PETER ANDREW WALTERS, KATHLEEN D.A. LOS