Patents by Inventor Kathleen Danenberg

Kathleen Danenberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of determining dihydropyrimidine dehydrogenase gene expression
    Publication number: 20030165840
    Abstract: The present invention relates to prognostic methods which are useful in medicine, particularly cancer chemotherapy. The object of the invention to provide a method for assessing Dihydropyrimidine dehydrogenase (DPD) expression levels in tissues and prognosticate the probable resistance of a patient's tumor to treatment with 5-FU based therapies by examination of the amount of DPD mRNA in a patient's tumor cells and comparing it to a predetermined threshold expression level. More specifically, the invention provides to oligonucleotide primer pairs DPD3A and DPD3B and methods comprising their use for detecting levels of Dihydropyrimidine dehydrogenase (DPD) mRNA.
    Type: Application
    Filed: June 13, 2001
    Publication date: September 4, 2003
    Inventor: Kathleen Danenberg
  • Quantitative measurement of gene expression based on isolation of RNA from formalin-fixed paraffin-embedded tissue specimens
    Patent number: 6613518
    Abstract: Methods are disclosed for rapid, reliable and simple isolation of RNA from formalin-fixed paraffin-embedded tissue samples. RNA purified in this manner can be used for quantitative measurement gene expression levels. The tissue sample can be a tumor or other pathological tissue.
    Type: Grant
    Filed: March 1, 2001
    Date of Patent: September 2, 2003
    Assignee: University of Sourthern California
    Inventors: Kathleen Danenberg, Peter V. Danenberg, Steven Swenson
  • Isolation of RNA, DNA and proteins from formalin-fixed paraffin-embedded tissue specimens
    Patent number: 6610488
    Abstract: Methods are disclosed for rapid, reliable and simple isolation of RNA, DNA and proteins from formalin-fixed paraffin-embedded tissue samples. RNA purified in this manner can be used to monitor gene expression levels. The tissue sample can be a tumor or other pathological tissue.
    Type: Grant
    Filed: March 1, 2001
    Date of Patent: August 26, 2003
    Assignee: University of Southern California
    Inventors: Kathleen Danenberg, Peter V. Danenberg, Steven Swenson
  • Isolation of RNA from formalin-fixed paraffin-embedded tissue specimens
    Patent number: 6428963
    Abstract: Methods are disclosed for rapid, reliable and simple isolation of RNA from formalin-fixed paraffin-embedded tissue samples. RNA purified in this manner can be used to monitor gene expression levels. The tissue sample can be a tumor or other pathological tissue.
    Type: Grant
    Filed: March 1, 2001
    Date of Patent: August 6, 2002
    Assignee: University of Southern California
    Inventors: Kathleen Danenberg, Peter V. Danenberg, Steven Swenson
  • Isolation of RNA, DNA and proteins from formalin-fixed paraffin-embedded tissue specimens
    Publication number: 20020009795
    Abstract: Methods are disclosed for rapid, reliable and simple isolation of RNA, DNA and proteins from formalin-fixed paraffin-embedded tissue samples. RNA purified in this manner can be used to monitor gene expression levels. The tissue sample can be a tumor or other pathological tissue.
    Type: Application
    Filed: March 1, 2001
    Publication date: January 24, 2002
    Inventors: Kathleen Danenberg, Peter V. Danenberg, Steven Swenson
  • Isolation of RNA from formalin-fixed paraffin-embedded tissue specimens
    Publication number: 20020009794
    Abstract: Methods are disclosed for rapid, reliable and simple isolation of RNA from formalin-fixed paraffin-embedded tissue samples. RNA purified in this manner can be used to monitor gene expression levels. The tissue sample can be a tumor or other pathological tissue.
    Type: Application
    Filed: March 1, 2001
    Publication date: January 24, 2002
    Inventors: Kathleen Danenberg, Peter V. Danenberg, Steven Swenson
  • Quantitative measurement of gene expression based on isolation of RNA from formalin-fixed paraffin-embedded tissue specimens
    Publication number: 20010029018
    Abstract: Methods are disclosed for rapid, reliable and simple isolation of RNA from formalin-fixed paraffin-embedded tissue samples. RNA purified in this manner can be used for quantitative measurement gene expression levels. The tissue sample can be a tumor or other pathological tissue.
    Type: Application
    Filed: March 1, 2001
    Publication date: October 11, 2001
    Inventors: Kathleen Danenberg, Peter V. Danenberg, Steven Swensen
  • Method for isolation of RNA from formalin-fixed paraffin-embedded tissue specimens
    Patent number: 6248535
    Abstract: Methods are disclosed for rapid, reliable and simple isolation of RNA from formalin-fixed paraffin-embedded tissue samples. RNA purified in this manner can be used to monitor gene expression levels. The tissue sample can be a tumor or other pathological tissue.
    Type: Grant
    Filed: December 20, 1999
    Date of Patent: June 19, 2001
    Assignee: University of Southern California
    Inventors: Kathleen Danenberg, Peter V. Danenberg, Steven Swenson