Abstract: Examples relate to pivotable fluid collection device tubing connectors. A urine collection system may include a urine collection device and a tube connector. The urine collection device includes a sump positioned within the urine collection device, a fluid impermeable barrier at least partially defining an opening, and a fluid permeable body within the urine collection device positioned to be proximate to a urethra of a user when the urine collection device is in use. The tube connector is positioned at least partially outside the urine collection device and has a first end region proximate to the urine collection device and a second end region distal to the urine collection device that is in fluid communication with the sump. The tube connector is adjustable between multiple orientations that adjust positioning of the second end region relative to the first end region whilst functionally maintaining the fluid communication between the second end region and the sump.

Abstract: Examples relate to fluid collection devices, systems, and methods of collecting fluid from wearers. The fluid collection devices include a retention means for maintaining the position of the fluid collection device with respect to the wearer.

Abstract: Example fluid collection devices and methods of use arc described. The fluid collection devices include a fluid impermeable barrier, a fluid permeable body, and two arms. The fluid impermeable barrier at least partially defines a chamber, and an opening configured to be positioned adjacent to a urethra. The fluid permeable body is positioned at least partially within the chamber to extend across at least a portion of the opening and configured to wick fluid away from the opening. The arms include an adhesive surface oriented towards the fluid impermeable barrier. The arms arc positioned on the fluid impermeable barrier to attach to at least one of an abdominal region, a pubic region, or a pelvic region of the user when the opening of the fluid impermeable barrier is positioned at least proximate to the urethra of the user.

Abstract: Examples relate to fluid collection devices, systems, and methods of collecting fluid from wearers. The fluid collection devices include a retention means for maintaining the position of the fluid collection device with respect to the wearer.

Abstract: Example fluid collection systems and methods of collecting fluid are described. The fluid collection system includes a fluid collection device and one or more straps secured or securable to the fluid collection device. The one or more straps are configured to wrap around the user to secure the fluid collection device adjacent to the urethra of the user.

Abstract: An example fluid collection assembly (100) includes a sheath (102) and a base (104). The sheath includes a fluid impermeable barrier (106) formed from at least a first panel (108) and a second panel (110). The first panel and the second panel at least partially define a chamber (112) therebetween. The fluid impermeable barrier also defines a fluid outlet (118) at a distal end of the sheath and an opening (114) at a proximal end of the sheath. The sheath also includes at least one porous material (122) disposed in the chamber. The base is permanently secured or configured to be permanently secured to the sheath. The base defines an aperture (124) that is aligned with the opening when the base is permanently attached to the sheath. The base is configured to be secured to a region about a penis of an individual with the aperture positioned over the penis.

Abstract: An example fluid collection assembly includes a sheath and a base. The sheath includes a fluid impermeable barrier having a proximal region and a distal region extending from the proximal region. The proximal region exhibits a first width and the distal region exhibits a second width that is less than the first width. The proximal region defines an opening and the distal region defines a fluid outlet. The fluid impermeable barrier define a chamber. The sheath also includes at least one porous material disposed in the chamber. The base may be attached to or configured to be attached to the sheath. The base defines an aperture that is aligned with the opening when the base is attached to the sheath. The base is configured to be secured to a region about a penis of an individual with the aperture positioned over the penis.

Abstract: Methods and systems for determining allele status at a plurality of loci. A first plurality of loci are amplified, in a single reaction vessel, with a plurality of fluorescently labeled detection reagents. A first detection reagent that is specific for the most prevalent allele in a population is labeled with a first fluorescent moiety. A second detection reagent that is specific for a minor allele in the population is labeled with a second fluorescent moiety that is distinguishable from the first fluorescent moiety. A fluorescent signal corresponding to the first fluorescent moiety and the second fluorescent moiety in the reaction vessel is detected. When the contribution of the second fluorescent moiety does not satisfy a threshold, report that the subject does not carry the second allele at any of the first plurality of genomic loci. When the contribution of the second fluorescent satisfies the threshold, perform secondary allele detection assays.

Abstract: Examples relate to fluid collection devices, systems, and methods of collecting fluid from wearers. The fluid collection devices include a retention means for maintaining the position of the fluid collection device with respect to the wearer.

Abstract: Embodiments disclosed herein include fluid collection assemblies with at least one securement body. In an embodiment, a fluid collection assembly is disclosed. The fluid collection assembly includes a fluid impermeable barrier at least defining a chamber, at least one opening, and a fluid outlet. The fluid collection assembly also includes at least one porous material disposed in the chamber and at least one securement body configured to limit movement of the fluid collection assembly relative to a region about a urethral opening of a patient. The at least one securement body includes at least one of a plurality of fibers exhibiting an average lateral dimension of about 5 ?m or less, a plurality of suction cups, or at least one friction material exhibiting a coefficient of static friction that is greater than at least a portion of the at least one porous material.

Abstract: An example device suitable for collecting and transporting urine away from the body of a person may include a fluid impermeable housing defining an internal volume. The device can include a porous material disposed within the internal volume. The fluid impermeable housing can define an opening in fluid communication with the internal volume. The porous material includes a contact surface and first and second sidewalls. The sidewalls can extend from the contact surface, for example, substantially orthogonal to the contact surface, or laterally and inwardly from the contact surface at an acute angle.

Abstract: An example female fluid collection assembly includes a fluid impermeable barrier. The fluid impermeable barrier at least defines a chamber and an opening. The female fluid collection assembly also includes at least one porous material disposed in the chamber. The porous material extends across the opening. In an embodiment, the portion of the porous material that extends across the opening include a protrusion that extends outwardly from the opening. In an embodiment, the porous material includes at least one expandable material that is configured to expand (e.g., increase in volume) when the expandable material exposed to one or more bodily fluids (e.g., urine).

Abstract: A device suitable for collecting and transporting urine away from the body of a person including a casing defining an internal volume and an opening. The casing can include a compressible material which is elastically deformable when the device is disposed in a pubic region of a female user. The device can include a porous material disposed within the internal volume and in fluid communication with the opening. The porous material can wick, draw, or direct fluid, such as urine, away from the pubic region of the female user and into the internal volume. The device can include a fluid conduit disposed within the internal volume and enabling extraction of fluid from the internal volume. The device can include a fluid impermeable housing disposed within the internal volume and adhered or otherwise affixed to the casing.

Abstract: Example fluid collection devices and methods of using the fluid collection devices are described. The fluid collection devices include a fluid impermeable barrier, an enlarged base, and a fluid permeable body. The fluid impermeable barrier has a first lateral dimension and at least partially defining a chamber, an aperture configured to receive a conduit therethrough, and an opening. The base extends from the fluid impermeable barrier distal to the aperture and has a second lateral dimension greater than the first lateral dimension. The fluid permeable body is positioned at least partially within the chamber to extend across at least a portion of the opening.

Abstract: A screening method is provided for a specific HLA allele in an individual, including but not limited to an HLA-A*31:01 allele. Also included are methods for treating an individual in need of a medication, which can induce ADRs associated with a specific HLA allele, and a kit including detection reagents used in the screening method.

Abstract: Disclosed herein are methods, devices and systems of treating dysfunctional biochemical pathway(s) using an individualized treatment plan (ITP) of metabolic support intervention(s) for a patient. The ITP has metabolic support intervention(s) that restore proper functioning of biochemical pathway(s) correcting dysfunction(s) therein. Methods can include determining if the biochemical pathway(s) are dysfunctional by subjecting, via a bio-communication device, the patient to a noninvasive test that includes simulating one or more stimuli that are indicative of the biochemical pathway(s)' s functioning.

Abstract: Provided herein is a three-dimensional scaffold composition comprising randomly oriented fibers, wherein the fibers comprise a polyethylene glycol-polylactic acid block copolymer (PEG-PLA) and a poly(lactic-co-glycolic acid) (PLGA). Also provided are methods for using the three-dimensional scaffolds described herein.

Abstract: Provided herein is a three-dimensional scaffold composition comprising randomly oriented fibers, wherein the fibers comprise a polyethylene glycol-polylactic acid block copolymer (PEG-PLA) and a poly(lactic-co-glycolic acid) (PLGA). Also provided are methods for using the three-dimensional scaffolds described herein.

Abstract: The present invention relates to swimming fins used for strength training in fitness swimming and performance swimming. A swimming fin comprises a fin body having top and bottom surfaces, and proximal and distal ends, the fin body defining an opening at the proximal side and configured to receive a foot. A portion of the distal edge is scalloped.

Abstract: The present invention relates to swimming paddles used for strength training in fitness swimming and performance swimming. A swimming paddle comprises an oversized paddle body having top and bottom surfaces, proximal and distal sides, and lateral and medial sides, the paddle body having a hand placement portion for placing a hand thereon. The swimming paddle further comprises a hand securing portion configured to secure a hand to the paddle body. A portion of a side of the paddle body is scalloped.