Patents by Inventor Kathleen J. Reis

Kathleen J. Reis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Simultaneous determination of forward and reverse ABO blood group
    Patent number: 6955889
    Abstract: Simultaneous forward and reverse blood group testing is described using both a visual detection system and a fluorescent based labeling and detection system. Forward and reverse tests could be performed separately, but A and B agglutinates can be detected and discriminated simultaneously.
    Type: Grant
    Filed: June 1, 2000
    Date of Patent: October 18, 2005
    Assignee: Ortho-Clinical Diagnostics, Inc.
    Inventors: Thomas J. Mercolino, Kathleen J. Reis
  • Agglutination reaction and separation vessel
    Patent number: 6187583
    Abstract: A vessel for conducting blood cell agglutination assays is disclosed. A barrier retains reactants in an upper chamber during incubation, then, in response to a force, permits reagents to enter a lower chamber containing a matrix for separating agglutination.
    Type: Grant
    Filed: May 28, 1998
    Date of Patent: February 13, 2001
    Inventors: Walter Milchanoski, Milan Jorik, Kathleen J. Reis, Diane E. Bechtold, Linda Davis, Thomas M. Setcavage
  • Foil sealed cassette for agglutination reactions and liner therefor
    Patent number: 5780248
    Abstract: A vessel for conducting blood cell agglutination assays is disclosed. A barrier retains reactants in an upper chamber during incubation, then, in response to a force, permits reagents to enter a lower chamber containing a matrix for separating agglutination.
    Type: Grant
    Filed: February 2, 1996
    Date of Patent: July 14, 1998
    Assignee: Ortho Diagnostic Systems, Inc.
    Inventors: Walter Milchanoski, Milan Jorik, Kathleen J. Reis, Diane E. Bechtold, Linda Davis, Thomas M. Setcavage, Donald M. Davies
  • Column agglutination assay and device using biphasic centrifugation
    Patent number: 5650068
    Abstract: The present invention provides a method and device for detecting the presence of binding ligands, especially blood group antigens or antibodies thereto, which utilize a matrix of substantially noncompressable microparticles, which matrix provides superior performance in allowing movement of nonagglutinated reactants, especially red blood cells, while constraining, preferably in a so-called "band formation" agglutinated reactants, especially red blood cells. The device of the invention further comprises a chamber the transverse cross-sectional shape thereof being an ellipse, or preferably a flattened ellipse with two sides parallel to the longitudinal axis.
    Type: Grant
    Filed: April 16, 1996
    Date of Patent: July 22, 1997
    Assignee: Ortho Diagnostic Systems Inc.
    Inventors: Rosemary K. Chachowski, Thomas M. Setcavage, Kathleen J. Reis
  • Column agglutination assay and device using biphasic centrifugation
    Patent number: 5552064
    Abstract: The present invention provides a method and device for detecting the presence of binding ligands, especially blood group antigens or antibodies thereto, which utilize a matrix of substantially noncompressable microparticles, which matrix provides superior performance in allowing movement of nonagglutinated reactants, especially red blood cells, while constraining, preferably in a so-called "band formation" agglutinated reactants, especially red blood cells.
    Type: Grant
    Filed: August 26, 1993
    Date of Patent: September 3, 1996
    Assignee: Ortho Diagnostic Systems, Inc.
    Inventors: Rosemary K. Chachowski, Thomas M. Setcavage, Kathleen J. Reis
  • Agglutination reaction and separation vessel
    Patent number: 5491067
    Abstract: A vessel for conducting blood cell agglutination assays is disclosed. A barrier retains reactants in an upper chamber during incubation, then, in response to a force, permits reagents to enter a lower chamber containing a matrix for separating agglutination.
    Type: Grant
    Filed: July 16, 1993
    Date of Patent: February 13, 1996
    Assignee: Ortho Diagnostic Systems Inc.
    Inventors: Thomas M. Setcavage, Kathleen J. Reis, Donald M. Davies, Edward J. Mazur
  • Novel type VI bacterial Fc receptors
    Patent number: 5085984
    Abstract: Novel Fc receptors, denoted type VI, are disclosed as reacting with rat immunoglobulins with a reasonable affinity. These receptors, or the microorganisms which produce them, are useful in immunoassays.
    Type: Grant
    Filed: April 23, 1990
    Date of Patent: February 4, 1992
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Michael D. P. Boyle, Kathleen J. Reis
  • Type VI bacterial FC receptors
    Patent number: 4977082
    Abstract: Novel Fc receptors, denoted type VI, are disclosed as reacting with rat immunoglobulins with a reasonable affinity. The type VI receptors are isolated from Streptococcus zooepidemicus strain s212 (ATCC 53698) and Streptococcus zooepidemicus strain RSS-212 (ATCC 53697) culture supernatants. These receptors, or the microorganisms which produce them, are useful in immunoassays.
    Type: Grant
    Filed: November 9, 1988
    Date of Patent: December 11, 1990
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Michael D. P. Boyle, Kathleen J. Reis
  • Streptococcal fc rc
    Patent number: 4900660
    Abstract: Proteinaceous, antigenic factor derived from a group C Streptococcus which is receptor for the Fc region of IgG, a method for its preparation and immunoassay and antigen detection methods employing the receptor.
    Type: Grant
    Filed: November 25, 1985
    Date of Patent: February 13, 1990
    Assignee: University of Florida
    Inventors: Michael D. P. Boyle, Kathleen J. Reis, Elia M. Ayoub