Patents by Inventor Kathleen M. George

Kathleen M. George has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mycolactone and related compounds, compositions and methods of use
    Patent number: 6680055
    Abstract: The present invention provides, inter alia, polyketide macrolides including a polyketide macrolide of the structure wherein R1-R5 are the same or different and each is independently selected from the group consisting of hydrogen, R6, a C(O)R7, a C(S)R7, a C(O)NHR7, and a C(S)NHR7, each occurrence of R6 is independently selected from the group consisting of a C1-C6 alkyl, a C5-C12 aryl, and a sugar, each occurrence of R7 is independently selected from the group consisting of hydrogen, a C1-C6 alkyl, and a C5-C12 aryl, and wherein R1 and R2, R2 and R3, and/or R4 and R5 can be taken together to form a ketal ring. Also provided are asceptic mixtures of polyketide macrolides isolated from M.
    Type: Grant
    Filed: February 27, 2002
    Date of Patent: January 20, 2004
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Pamela L. C. Small, Kathleen M. George