Patents by Inventor Kathleen M. Metters

Kathleen M. Metters has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD OF TREATING ATHEROSCLEROSIS, DYSLIPIDEMIAS AND RELATED CONDITIONS
    Publication number: 20110118292
    Abstract: A method of treating atherosclerosis is disclosed wherein nicotinic acid or another nicotinic acid receptor agonist is administered to the patient in combination with a DP receptor antagonist. The DP receptor antagonist is administered to reduce, prevent or eliminate flushing that may otherwise occur.
    Type: Application
    Filed: January 24, 2011
    Publication date: May 19, 2011
    Inventors: Kang Cheng, M. Gerard Waters, Kathleen M. Metters, Gary O'Neill
  • Method of Treating Atherosclerosis, Dyslipidemias and Related Conditions and Pharmaceutical Compositions
    Publication number: 20100076002
    Abstract: A method of treating atherosclerosis is disclosed wherein nicotinic acid or another nicotinic acid receptor agonist is administered to the patient in combination with a DP receptor antagonist. The DP receptor antagonist is administered to reduce, prevent or eliminate flushing that may otherwise occur.
    Type: Application
    Filed: November 30, 2009
    Publication date: March 25, 2010
    Inventors: Kang Cheng, M. Gerard Waters, Kathleen M. Metters, Gary O'Neill
  • Method of Treating Atherosclerosis, dyslipidemias and related conditions
    Publication number: 20090233977
    Abstract: A method of treating atherosclerosis is disclosed wherein nicotinic acid or another nicotinic acid receptor agonist is administered to the patient in combination with a DP receptor antagonist. The DP receptor antagonist is administered to reduce, prevent or eliminate flushing that may otherwise occur.
    Type: Application
    Filed: May 21, 2009
    Publication date: September 17, 2009
    Inventors: Kang Cheng, M. Gerard Waters, Kathleen M. Metters, Gary O'Neill
  • Method for treating ocular hypertension
    Publication number: 20040254230
    Abstract: This invention relates to potent selective agonists of the EP4 subtype of prostaglandin E2 receptors, their use or a formulation thereof in the treatment of glaucoma and other conditions that are related to elevated intraocular pressure in the eye of a patient. This invention also relates to the use of such compounds to provide a neuroprotective effect to the eye of mammalian species, particularly humans.
    Type: Application
    Filed: May 4, 2004
    Publication date: December 16, 2004
    Inventors: Miller J. Ogidigben, Robert N. Young, Kathleen M. Metters, Deborah M. Slipetz
  • Method of treating atherosclerosis, dyslipidemias and related conditions
    Publication number: 20040229844
    Abstract: A method of treating atherosclerosis is disclosed wherein nicotinic acid or another nicotinic acid receptor agonist is administered to the patient in combination with a DP receptor antagonist. The DP receptor antagonist is administered to reduce, prevent or eliminate flushing that may otherwise occur.
    Type: Application
    Filed: May 13, 2004
    Publication date: November 18, 2004
    Inventors: Kang Cheng, M. Gerard Waters, Kathleen M. Metters, Gary O'Neill
  • Ep4 receptor agonist, compositions and methods thereof
    Publication number: 20040204590
    Abstract: This invention relates to potent selective agonists of the EP4 subtype of prostaglandin E2 receptors, their use or a formulation thereof in the treatment of glaucoma and other conditions which are related to elevated intraocular pressure in the eye of a patient. This invention further relates to the use of the compounds of this invention for mediating the bone modeling and remodeling processes of the osteoblasts and osteoclasts.
    Type: Application
    Filed: April 22, 2004
    Publication date: October 14, 2004
    Inventors: Miller J. Ogidigben, Robert N Young, Kathleen M Metters, Deborah M Slipetz
  • LTD.sub.4 receptor and photoaffinity probe
    Patent number: 5310884
    Abstract: The LTD.sub.4 receptor has been defined by radioligand binding studies as a member of the family of G-protein coupled receptors. A photoactivable azido derivative of LTD.sub.4 ([.sup.125 I]Azido-LTD.sub.4) has been synthesized for use as a photoaffinity probe. Photoactivation of ([.sup.125 I]Azido-LTD.sub.4 under equilibrium binding conditions revealed the selective radiolabeling of a 45 kDa protein in guinea-pig lung membranes, as visualized by SDS-PAGE and autoradiography.
    Type: Grant
    Filed: April 3, 1992
    Date of Patent: May 10, 1994
    Assignee: Merck Frosst Canada, Inc.
    Inventors: Robert Zamboni, Kathleen M. Metters