Patents by Inventor Kathleen M. Schmainda

Kathleen M. Schmainda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MRI method for measuring tumor hemodynamic parameters in the presence of contrast agent extravasation
    Patent number: 7567832
    Abstract: One or two sets of time course NMR data are acquired using an EPI pulse sequence in which either or both gradient recalled echo NMR signals and spin-echo NMR signals are acquired after bolus injection of a contrast agent. T2* relaxation rates for GE and T2 relaxation rates for SE are calculated from the acquired NMR signals and are corrected for extravasation of contrast agent into surrounding tissues. The gradient-echo signals and spin-echo NMR signals are employed along with the T2* and T2 relaxation rates to calculate hemodynamic parameter maps which are used as a measure of tumor angiogenesis.
    Type: Grant
    Filed: August 12, 2005
    Date of Patent: July 28, 2009
    Assignee: The MCW Research Foundation
    Inventors: Kathleen M. Schmainda, Christopher Quarles, B. Douglas Ward
  • Evaluation of tumor angiogenesis using magnetic resonance imaging
    Patent number: 6807441
    Abstract: Two sets of time course NMR data are acquired using an EPI pulse sequence in which both gradient recalled echo NMR signals and spin-echo NMR signals are acquired after bolus injection of a contrast agent. The gradient-echo signals and spin-echo NMR signals are employed to calculate rCBV maps which are corrected for contrast leakage and used as a measure of tumor angiogenesis. Both the gradient echo and spin echo signals are employed to calculate a &Dgr;R2 weighting ratio which is also a measure of tumor angiogenesis.
    Type: Grant
    Filed: May 18, 2001
    Date of Patent: October 19, 2004
    Assignee: The MCW Research Foundation Inc.
    Inventor: Kathleen M. Schmainda
  • Evaluation of tumor angiogenesis using magnetic resonance imaging
    Publication number: 20020026116
    Abstract: Two sets of time course NMR data are acquired using an EPI pulse sequence in which both gradient recalled echo NMR signals and spin-echo NMR signals are acquired after bolus injection of a contrast agent. The gradient-echo signals and spin-echo NMR signals are employed to calculate rCBV maps which are corrected for contrast leakage and used as a measure of tumor angiogenesis. Both the gradient echo and spin echo signals are employed to calculate a &Dgr;R2 weighting ratio which is also a measure of tumor angiogenesis.
    Type: Application
    Filed: May 18, 2001
    Publication date: February 28, 2002
    Inventor: Kathleen M. Schmainda