Patents by Inventor Kathrin Klein

Kathrin Klein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for determining the predisposition of a patient to changed biotransformation and to the development of undesired drug effects in a treatment of the patient with atrovastatin
    Patent number: 9528156
    Abstract: A method for determining a predisposition of a patient to the development of muscular diseases and/or to changed biotransformation in a treatment of the patient with atorvastatin is disclosed. The presence of at least one single nucleotide polymorphism (SNP) in the UGT1A3 gene (uridine diphosphate glucuronosyltransferase gene 1A3) and/or an increased UGT1A3 gene expression is determined in a biological sample of the patient. The disclosure further relates to oligonucleotides that can be used in the method and to diagnostic kits that use the oligonucleotides.
    Type: Grant
    Filed: February 23, 2010
    Date of Patent: December 27, 2016
    Assignee: Robert Bosch GmbH
    Inventors: Kathrin Klein, Stephan Riedmaier, Ulrich Zanger
  • Method for Determining the Predisposition of a Patient to Changed Biotransformation and to the Development of Undesired Drug Effects in a Treatment of the Patient with Atrovastatin
    Publication number: 20120107814
    Abstract: A method for determining a predisposition of a patient to the development of muscular diseases and/or to changed biotransformation in a treatment of the patient with atorvastatin is disclosed. The presence of at least one single nucleotide polymorphism (SNP) in the UGT1A3 gene (uridine diphosphate glucuronosyltransferase gene 1A3) and/or an increased UGT1A3 gene expression is determined in a biological sample of the patient. The disclosure further relates to oligonucleotides that can be used in the method and to diagnostic kits that use the oligonucleotides.
    Type: Application
    Filed: February 23, 2010
    Publication date: May 3, 2012
    Applicant: Robert Bosch GmbH
    Inventors: Kathrin Klein, Stephan Riedmaier, Ulrich Zanger
  • Preparation of acariogenic sugar substitutes
    Patent number: 7208307
    Abstract: The invention relates to sucrose isomerases, to DNA sequences that code for sucrose isomerases, and to novel processes for the production of non-cariogenic sugars.
    Type: Grant
    Filed: June 18, 2003
    Date of Patent: April 24, 2007
    Assignee: Sudzucker Aktiengesellschaft
    Inventors: Ralf Mattes, Kathrin Klein, Hurbert Schiweck, Markwart Kunz, Mohammed Munir
  • Preparation of acariogenic sugar substitutes
    Patent number: 6884611
    Abstract: The invention relates to sucrose isomerases, to DNA sequences that code for sucrose isomerases, and to novel processes for the production of non-cariogenic sugars.
    Type: Grant
    Filed: February 4, 2002
    Date of Patent: April 26, 2005
    Assignee: Sudzucker Aktiengesellschaft
    Inventors: Ralf Mattes, Kathrin Klein, Hurbert Schiweck, Markwart Kunz, Mohammed Munir
  • Preparation of acariogenic sugar substitutes
    Publication number: 20030207437
    Abstract: The invention relates to sucrose isomerases, to DNA sequences that code for sucrose isomerases, and to novel processes for the production of non-cariogenic sugars.
    Type: Application
    Filed: June 18, 2003
    Publication date: November 6, 2003
    Applicant: Sudzucker Aktiengesellschaft
    Inventors: Ralf Mattes, Kathrin Klein, Hurbert Schiweck, Markwart Kunz, Mohammed Munir
  • Preparation of acariogenic sugar substitutes
    Publication number: 20030203468
    Abstract: The invention relates to sucrose isomerases, to DNA sequences that code for sucrose isomerases, and to novel processes for the production of non-cariogenic sugars.
    Type: Application
    Filed: June 18, 2003
    Publication date: October 30, 2003
    Applicant: Sudzucker Aktiengesellschaft
    Inventors: Ralf Mattes, Kathrin Klein, Hurbert Schiweck, Markwart Kunz, Mohammed Munir
  • Preparation of acariogenic sugar substitutes
    Publication number: 20030087416
    Abstract: The invention relates to sucrose isomerases, to DNA sequences that code for sucrose isomerases, and to novel processes for the production of non-cariogenic sugars.
    Type: Application
    Filed: February 4, 2002
    Publication date: May 8, 2003
    Inventors: Ralf Mattes, Kathrin Klein, Hurbert Schiweck, Markwart Kunz, Mohammed Munir
  • Preparation of acariogenic sugar substitutes
    Patent number: 5985622
    Abstract: The invention relates to sucrose isomerases, to DNA sequences coding therefor, and to novel processes for the production of non-cariogenic sugars.
    Type: Grant
    Filed: January 21, 1997
    Date of Patent: November 16, 1999
    Assignee: Sudzucker Aktiengesellschaft
    Inventors: Ralf Mattes, Kathrin Klein, Hubert Schiweck, Markwart Kunz, Mohammed Munir
  • Sucrose metabolism mutants
    Patent number: 5985668
    Abstract: The invention relates to sucrose isomerases, to DNA sequences coding therefor, and to novel processes for producing noncariogenic sugars.
    Type: Grant
    Filed: June 27, 1996
    Date of Patent: November 16, 1999
    Assignee: Sudzucker Aktiengesellschaft Mannheim/Ochsenfurt
    Inventors: Ralf Mattes, Kathrin Klein, Sabine Stegmaier
  • DNA's encoding sucrose isomerase and palatinase
    Patent number: 5786140
    Abstract: The invention relates to sucrose isomerases, to DNA sequences coding therefor, and to novel processes for the production of non-cariogenic sugars.
    Type: Grant
    Filed: January 18, 1995
    Date of Patent: July 28, 1998
    Assignee: Sudzucker Aktiengesellschaft Mannheim/Ochsenfurt
    Inventors: Ralf Mattes, Kathrin Klein, Hubert Schiweck, Markwart Kunz, Mohammad Munir