Patents by Inventor Kathryn A. Hanley

Kathryn A. Hanley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

Recombinant attenuated dengue viruses comprising a deletion in the 3? untranslated region and additional attenuating mutations induced by chemical mutagenesis

Patent number: 8039003

Abstract: The invention provides compositions featuring an attenuated dengue virus mutant or an attenuated chimeric dengue virus mutant.

Type: Grant

Filed: March 2, 2009

Date of Patent: October 18, 2011

Assignee: The United States of America as represented by the Secretary, Department of Health and Human Services

Inventors: Stephen S. Whitehead, Brian R. Murphy, Kathryn A. Hanley, Joseph E. Blaney
DEVELOPMENT OF MUTATIONS USEFUL FOR ATTENUATING DENGUE VIRUSES AND CHIMERIC DENGUE VIRUSES

Publication number: 20090263424

Abstract: A menu of mutations was developed that is useful in fine-tuning the attenuation and growth characteristics of dengue virus vaccines.

Type: Application

Filed: March 2, 2009

Publication date: October 22, 2009

Applicant: Government of the United States of America, as represented by the Secretary, Department Health

Inventors: Stephen S. Whitehead, Brian R. Murphy, Kathryn A. Hanley, Joseph E. Blaney
DENGUE TETRAVALENT VACCINE CONTAINING A COMMON 30 NUCLEOTIDE DELETION IN THE 3' -UTR OF DENGUE TYPES 1, 2, 3, AND 4 OR ANTIGENIC CHIMERIC DENGUE VIRUSES 1, 2, 3, AND 4

Publication number: 20090258036

Abstract: The invention relates to a dengue virus tetravalent vaccine containing a common 30 nucleotide deletion (?30) in the 3?-untranslated region of the genome of dengue virus serotypes 1, 2, 3, and 4, or antigenic chimeric dengue viruses of serotypes 1, 2, 3, and 4.

Type: Application

Filed: March 4, 2009

Publication date: October 15, 2009

Applicant: Government of the United States of America, as represented by the Secretary, Department of Health

Inventors: Stephen S. Whitehead, Brian R. Murphy, Lewis Markoff, Barry Falgout, Joseph Blaney, Kathryn Hanley
Attenuated dengue virus comprising mutations in the NS3 gene

Patent number: 7560118

Abstract: A menu of mutations was developed that is useful in fine-tuning the attenuation and growth characteristics of dengue virus vaccines.

Type: Grant

Filed: June 2, 2006

Date of Patent: July 14, 2009

Assignee: The United States of America as represented by the Department of Health and Human Services

Inventors: Stephen S. Whitehead, Brian R. Murphy, Kathryn A. Hanley, Joseph E. Blaney
Dengue tetravalent vaccine containing a common 30 nucleotide deletion in the 3?-UTR of dengue types 1,2,3, and 4, or antigenic chimeric dengue viruses 1,2,3, and 4

Patent number: 7517531

Abstract: The invention relates to a dengue virus tetravalent vaccine containing a common 30 nucleotide deletion (?30) in the 3?-untranslated region of the genome of dengue virus serotypes 1, 2, 3, and 4, or antigenic chimeric dengue viruses of serotypes 1, 2, 3, and 4.

Type: Grant

Filed: October 21, 2004

Date of Patent: April 14, 2009

Assignee: The United States of America as represented by the Department of Health and Human Services

Inventors: Stephen S. Whitehead, Brian R. Murphy, Lewis Markoff, Barry Falgout, Joseph Blaney, Kathryn Hanley
Development of mutations useful for attenuating dengue viruses and chimeric dengue viruses

Patent number: 7226602

Abstract: A menu of mutations was developed that is useful in fine-tuning the attenuation and growth characteristics of dengue virus vaccines.

Type: Grant

Filed: November 21, 2003

Date of Patent: June 5, 2007

Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services

Inventors: Stephen S. Whitehead, Brian R. Murphy, Kathryn A. Hanley, Joseph E. Blaney
Development of mutations useful for attenuating dengue viruses and chimeric dengue viruses

Publication number: 20070092534

Abstract: A menu of mutations was developed that is useful in fine-tuning the attenuation and growth characteristics of dengue virus vaccines.

Type: Application

Filed: June 2, 2006

Publication date: April 26, 2007

Inventors: Stephen Whitehead, Brian Murphy, Kathryn Hanley, Joseph Blaney
Dengue tetravalent vaccine containing a common 30 nucleotide deletion in the 3'-UTR of dengue types 1,2,3, and 4, or antigenic chimeric dengue viruses 1,2,3, and 4

Publication number: 20070009552

Abstract: The invention relates to a dengue virus tetravalent vaccine containing a common 30 nucleotide deletion (?30) in the 3?-untranslated region of the genome of dengue virus serotypes 1, 2, 3, and 4, or antigenic chimeric dengue viruses of serotypes 1, 2, 3, and 4.

Type: Application

Filed: October 21, 2004

Publication date: January 11, 2007

Inventors: Stephen Whitehead, Brian Murphy, Lewis Markoff, Barry Falgout, Joseph Blaney, Kathryn Hanley
Development of mutations useful for attenuating dengue viruses and chimeric dengue viruses

Publication number: 20050010043

Abstract: A menu of mutations was developed that is useful in fine-tuning the attenuation and growth characteristics of dengue virus vaccines.

Type: Application

Filed: November 21, 2003

Publication date: January 13, 2005

Inventors: Stephen Whitehead, Brian Murphy, Kathryn Hanley, Joseph Blaney

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