Patents by Inventor Kathryn A. Losee

Kathryn A. Losee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Reaction products of pyrazolo[1,5-c]quinazoline derivatives and proline derivatives and methods for reducing blood pressure while inhibiting allergic reactions with them
    Patent number: 4307099
    Abstract: Compounds of the following structure are provided ##STR1## wherein R.sup.1 is hydrogen or lower alkanoyl, R.sup.2 is hydrogen or lower alkyl, and R.sup.3 is hydrogen, lower alkyl or trifluoromethyl. The above compounds have useful hypotensive activity and anti-allergy activity.
    Type: Grant
    Filed: June 25, 1980
    Date of Patent: December 22, 1981
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: George B. Mackaness, Kathryn A. Losee
  • Mercaptoacylpiperazine carboxylic acid compounds
    Patent number: 4198509
    Abstract: The mercaptoacylpiperazine carboxylic acid compounds which have the formula ##STR1## wherein R, R.sub.3 and R.sub.4 each is hydrogen or lower alkyl;R.sub.1 is lower alkyl;R.sub.2 is hydrogen, lower alkanoyl, benzoyl or ##STR2## m is 0, 1 or 2; n is 1, 2 or 3, the sum of m+n being equal to 1, 2 or 3and salts thereof, are useful as hypotensive agents.
    Type: Grant
    Filed: October 30, 1978
    Date of Patent: April 15, 1980
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Kathryn A. Losee, Jack Bernstein
  • Mercaptoacylamino derivatives of heterocyclic carboxylic acids
    Patent number: 4154934
    Abstract: New mercaptoacyl derivatives of heterocyclic carboxylic acids which have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.
    Type: Grant
    Filed: August 11, 1978
    Date of Patent: May 15, 1979
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Jack Bernstein, Kathryn A. Losee