Patents by Inventor Kathryn E. Packman

Kathryn E. Packman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL COMBINATION TREATMENT FOR ACUTE MYELOID LEUKEMIA (AML)
    Publication number: 20230381215
    Abstract: The present invention relates to a pharmaceutical product comprising a) as a first component an inhibitor of the MDM2-p53 interaction; and b) as a second component cytarabine; as a combined preparation for the sequential or simultaneous use in the treatment of cancer, particularly AML.
    Type: Application
    Filed: April 3, 2023
    Publication date: November 30, 2023
    Inventors: Brian Higgins, Kathryn E. Packman, Gwen Nichols
  • INHIBITORS OF BRUTON'S TYROSINE KINASE AND METHODS OF THEIR USE
    Publication number: 20230013755
    Abstract: The present disclosure is directed to the use of a compound of Formula (III) in the treatment of malignancies.
    Type: Application
    Filed: June 2, 2022
    Publication date: January 19, 2023
    Inventors: Sriram BALASUBRAMANIAN, Ivo CORNELISSEN, Yue GUO, Jocelyn H. LEU, Kathryn E. PACKMAN, James Alexander PALMER, Ulrike PHILIPPAR, Navin RAO, Mark S. TICHENOR, Jennifer D. VENABLE, John J. M. WIENER, Xin MIAO
  • NOVEL COMBINATION TREATMENT FOR ACUTE MYELOID LEUKEMIA (AML)
    Publication number: 20220031726
    Abstract: The present invention relates to a pharmaceutical product comprising a) as a first component an inhibitor of the MDM2-p53 interaction; and b) as a second component cytarabine; as a combined preparation for the sequential or simultaneous use in the treatment of cancer, particularly AML.
    Type: Application
    Filed: May 19, 2021
    Publication date: February 3, 2022
    Inventors: Brian Higgins, Kathryn E. Packman, Gwen Nichols
  • Antibodies specific for DR5 and methods of use
    Patent number: 11214622
    Abstract: The present invention relates to bispecific antibodies comprising at least one antigen binding site specific for DR5 and at least one antigen binding site specific for FAP, antibodies specific for DR5, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Grant
    Filed: March 6, 2018
    Date of Patent: January 4, 2022
    Assignee: ROCHE GLYCART AG
    Inventors: Peter Bruenker, Sherif Daouti, Ningping Feng, Claudia Ferrara Koller, Guy Georges, Sandra Grau-Richards, Ralf Hosse, Christian Klein, Maximiliane Koenig, Joerg Moelleken, Ekkehard Moessner, Huifeng Niu, Kathryn E. Packman, Valeria Runza, Stefan Seeber, Pablo Umana, Inja Waldhauer, Huisheng Wang, Barbara Weiser
  • NOVEL COMBINATION TREATMENT FOR ACUTE MYELOID LEUKEMIA (AML)
    Publication number: 20200253999
    Abstract: The present invention relates to a pharmaceutical product comprising a) as a first component an inhibitor of the MDM2-p53 interaction; and b) as a second component cytarabine; as a combined preparation for the sequential or simultaneous use in the treatment of cancer, particularly AML.
    Type: Application
    Filed: February 19, 2020
    Publication date: August 13, 2020
    Inventors: Brian Higgins, Kathryn E. Packman, Gwen Nichols
  • BISPECIFIC ANTIBODIES SPECIFIC FOR FAP AND DR5, ANTIBODIES SPECIFIC FOR DR5 AND METHODS OF USE
    Publication number: 20190062453
    Abstract: The present invention relates to bispecific antibodies comprising at least one antigen binding site specific for DR5 and at least one antigen binding site specific for FAP, antibodies specific for DR5, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Application
    Filed: March 6, 2018
    Publication date: February 28, 2019
    Applicant: Roche Glycart AG
    Inventors: Peter Bruenker, Sherif Daouti, Ningping Feng, Claudia Ferrara Koller, Guy Georges, Sandra Grau-Richards, Ralf Hosse, Christian Klein, Maximiliane Koenig, Joerg Moelleken, Ekkehard Moessner, Huifeng Niu, Kathryn E. Packman, Valeria Runza, Stefan Seeber, Pablo Umana, lnja Waldhauer, Huisheng Wang, Barbara Weiser
  • Combination treatment for acute myeloid leukemia (AML)
    Patent number: 9956243
    Abstract: The present invention relates to a pharmaceutical product comprising a) as a first component an inhibitor of the MDM2-p53 interaction such as, for example: and b) as a second component cytarabine; as a combined preparation for the sequential or simultaneous use in the treatment of cancer.
    Type: Grant
    Filed: December 4, 2014
    Date of Patent: May 1, 2018
    Assignee: HOFFMANN-LA ROCHE INC.
    Inventors: Brian Higgins, Gwen Nichols, Kathryn E. Packman
  • Bispecific antibodies specific for FAP and DR5, antibodies specific for DR5
    Patent number: 9926379
    Abstract: The present invention relates to bispecific antibodies comprising at least one antigen binding site specific for DR5 and at least one antigen binding site specific for FAP, antibodies specific for DR5, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Grant
    Filed: April 1, 2014
    Date of Patent: March 27, 2018
    Assignee: ROCHE GLYCART AG
    Inventors: Peter Bruenker, Sherif Daouti, Ningping Feng, Claudia Ferrara Koller, Guy Georges, Sandra Grau-Richards, Ralf Hosse, Christian Klein, Maximiliane Koenig, Joerg Moelleken, Ekkehard Moessner, Huifeng Niu, Kathryn E. Packman, Valeria Runza, Stefan Seeber, Pablo Umana, Inja Waldhauer, Huisheng Wang, Barbara Weiser
  • NOVEL COMBINATION TREATMENT FOR ACUTE MYELOID LEUKEMIA (AML)
    Publication number: 20160303158
    Abstract: The present invention relates to a pharmaceutical product comprising a) as a first component an inhibitor of the MDM2-p53 interaction; and b) as a second component cytarabine; as a combined preparation for the sequential or simultaneous use in the treatment of cancer, particularly AML.
    Type: Application
    Filed: December 1, 2014
    Publication date: October 20, 2016
    Inventors: Brian Higgins, Kathryn E. Packman, Gwen Nichols
  • COMBINATION OF RO5503781 AND CAPECITABINE FOR CANCER THERAPY
    Publication number: 20160129033
    Abstract: There are provided pharmaceutical products comprising a) a first component comprising the compound of formula (A); and b) a second component comprising capecitabine for the simultaneous or sequential treatment of cancer, kits comprising said product as well as methods for treating cancer patients by administering said product.
    Type: Application
    Filed: June 16, 2014
    Publication date: May 12, 2016
    Inventors: Brian Higgins, Gwen Nichols, Kathryn E. Packman
  • COMBINATION OF RO5503781, CAPECITABINE AND OXALIPLANTIN FOR CANCER THERAPY
    Publication number: 20160129034
    Abstract: The present application discloses pharmaceutical products comprising a) as a first component a pharmaceutical composition comprising as an active ingredient a therapeutically effective amount of the compound of formula (A) or a pharmaceutically acceptable salt, ester or prodrug of said compound; b) a second component comprising a pharmaceutical composition comprising a therapeutically effective amount of capecitabine; and c) a third component comprising a pharmaceutical composition comprising a therapeutically effective amount of oxaliplatin. The application also discloses methods for the treatment of cancer using said products, as well as kits containing said products.
    Type: Application
    Filed: June 16, 2014
    Publication date: May 12, 2016
    Inventors: Brian Higgins, Gwen Nichols, Kathryn E. Packman
  • NOVEL COMBINATION TREATMENT FOR ACUTE MYELOID LEUKEMIA (AML)
    Publication number: 20150157603
    Abstract: The present invention relates to a pharmaceutical product comprising a) as a first component an inhibitor of the MDM2-p53 interaction; and b) as a second component cytarabine; as a combined preparation for the sequential or simultaneous use in the treatment of cancer, particularly AML.
    Type: Application
    Filed: December 4, 2014
    Publication date: June 11, 2015
    Inventors: Brian Higgins, Gwen Nichols, Kathryn E. Packman
  • BISPECIFIC ANTIBODIES SPECIFIC FOR FAP AND DR5, ANTIBODIES SPECIFIC FOR DR5 AND METHODS OF USE
    Publication number: 20140370019
    Abstract: The present invention relates to bispecific antibodies comprising at least one antigen binding site specific for DR5 and at least one antigen binding site specific for FAP, antibodies specific for DR5, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Application
    Filed: April 1, 2014
    Publication date: December 18, 2014
    Applicant: ROCHE GLYCART AG
    Inventors: Peter Bruenker, Sherif Daouti, Ningping Feng, Claudia Ferrara Koller, Guy Georges, Sandra Grau-Richards, Ralf Hosse, Christian Klein, Maximiliane Koenig, Joerg Moelleken, Ekkehard Moessner, Huifeng Niu, Kathryn E. Packman, Valeria Runza, Stefan Seeber, Pablo Umana, Inja Waldhauer, Huisheng Wang, Barbara Weiser