Patents by Inventor Kathryn Keenan

Kathryn Keenan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11519987
    Abstract: A method for temperature quantification using magnetic resonance fingerprinting (MRF) includes acquiring MRF data from a region of interest in a subject using an MRF pulse sequence with smoothly varying RF phase for MR resonant frequencies that is played out continuously. For each of a plurality of time intervals during acquisition of the MRF data the method further includes comparing a set of the MRF data associated with the time interval to an MRF dictionary to determine at least one quantitative parameter of the acquired MRF data, determining a temperature change based on the at least one quantitative parameter and generating a quantitative map of the temperature change in the region of interest. The region of interest can include aqueous and adipose tissue.
    Type: Grant
    Filed: April 5, 2021
    Date of Patent: December 6, 2022
    Assignees: Case Western Reserve University, The Regents of the University of Colorado, Government of the United States, As Represented by the Secretary of Commerce
    Inventors: Kathryn Keenan, Megan Poorman, Rasim Boyacioglu, Mark A. Griswold
  • Publication number: 20210311146
    Abstract: A method for temperature quantification using magnetic resonance fingerprinting (MRF) includes acquiring MRF data from a region of interest in a subject using an MRF pulse sequence with smoothly varying RF phase for MR resonant frequencies that is played out continuously. For each of a plurality of time intervals during acquisition of the MRF data the method further includes comparing a set of the MRF data associated with the time interval to an MRF dictionary to determine at least one quantitative parameter of the acquired MRF data, determining a temperature change based on the at least one quantitative parameter and generating a quantitative map of the temperature change in the region of interest. The region of interest can include aqueous and adipose tissue.
    Type: Application
    Filed: April 5, 2021
    Publication date: October 7, 2021
    Inventors: Kathryn Keenan, Megan Poorman, Rasim Boyacioglu, Mark A. Griswold
  • Patent number: 10809331
    Abstract: Provided herein are novel liquid crystal based devices for the facile measurement of temperature in an MRI system. The thermometers comprise a plurality of vessels wherein each vessel contains a liquid crystal composition having a unique phase transition temperature. By scanning with appropriate techniques, the state of the liquid crystals in each vessel can be assessed, and the temperature at the time of the scan can be determined by the state of the liquid crystal compositions. Also provided are novel vessels and assemblies of vessels that can be used as MRI thermometers and which are compatible with MRI phantoms.
    Type: Grant
    Filed: March 5, 2018
    Date of Patent: October 20, 2020
    Assignee: QalibreMD
    Inventors: Elizabeth Mirowski, Michael Snow, Kathryn Keenan
  • Publication number: 20190271750
    Abstract: Provided herein are novel liquid crystal based devices for the facile measurement of temperature in an MRI system. The thermometers comprise a plurality of vessels wherein each vessel contains a liquid crystal composition having a unique phase transition temperature. By scanning with appropriate techniques, the state of the liquid crystals in each vessel can be assessed, and the temperature at the time of the scan can be determined by the state of the liquid crystal compositions. Also provided are novel vessels and assemblies of vessels that can be used as MRI thermometers and which are compatible with MRI phantoms.
    Type: Application
    Filed: March 5, 2018
    Publication date: September 5, 2019
    Inventors: Elizabeth Mirowski, Michael Snow, Kathryn Keenan