Patents by Inventor Kathryn Taylor LINKENS

Kathryn Taylor LINKENS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3-(5-HYDROXY-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND USES THEREOF
    Publication number: 20230067476
    Abstract: The present disclosure provides a compound of Formula (I?): or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, stereoisomer, or tautomer thereof, wherein Rx, X1, X2, and R1 are as defined herein, and methods of making and using same.
    Type: Application
    Filed: November 8, 2021
    Publication date: March 2, 2023
    Inventors: Claire ADCOCK, Simone BONAZZI, Artiom CERNIJENKO, Philip LAM, Kathryn Taylor LINKENS, Hasnain Ahmed MALIK, Noel Marie-France THOMSEN, Michael Scott VISSER
  • 1,2,4-OXADIAZOLE DERIVATIVES AS LIVER X RECEPTOR AGONISTS
    Publication number: 20220340573
    Abstract: Provided herein are compounds and pharmaceutical compositions useful for treating meibomian gland dysfunction (MGD), comprising administering to a subject in need thereof a therapeutically effective amount of a compound of Formula (I) or a compound of Formula (I?), or pharmaceutical composition described herein.
    Type: Application
    Filed: June 6, 2022
    Publication date: October 27, 2022
    Inventors: Kelly D. BOSS, Yi FAN, Alec Nathanson FLYER, Declan HARDY, Zhihong HUANG, Kathryn Taylor LINKENS, Jon Christopher LOREN, Fupeng MA, Valentina MOLTENI, Duncan SHAW, Jeffrey SMITH, Catherine Fooks SOLOVAY
  • 1,2,4-oxadiazole derivatives as liver X receptor agonists
    Patent number: 11427586
    Abstract: Provided herein are compounds and pharmaceutical compositions useful for treating meibomian gland dysfunction (MGD), comprising administering to a subject in need thereof a therapeutically effective amount of a compound of Formula (I) or a compound of Formula (I?), or pharmaceutical composition described herein.
    Type: Grant
    Filed: November 23, 2020
    Date of Patent: August 30, 2022
    Assignee: NOVARTIS AG
    Inventors: Kelly D. Boss, Yi Fan, Alec Nathanson Flyer, Declan Hardy, Zhihong Huang, Kathryn Taylor Linkens, Jon Christopher Loren, Fupeng Ma, Valentina Molteni, Duncan Shaw, Jeffrey Smith, Catherine Fooks Solovay
  • 1,2,4-OXADIAZOLE DERIVATIVES AS LIVER X RECEPTOR AGONISTS
    Publication number: 20220064164
    Abstract: Provided herein are compounds and pharmaceutical compositions useful for treating meibomian gland dysfunction (MGD), comprising administering to a subject in need thereof a therapeutically effective amount of a compound of Formula (I) or a compound of Formula (I?), or pharmaceutical composition described herein.
    Type: Application
    Filed: November 23, 2020
    Publication date: March 3, 2022
    Inventors: Kelly D. BOSS, Yi FAN, Alec Nathanson FLYER, Declan HARDY, Zhihong HUANG, Kathryn Taylor LINKENS, Jon Christopher LOREN, Fupeng MA, Valentina MOLTENI, Duncan SHAW, Jeffrey SMITH, Catherine Fooks SOLOVAY
  • 3-(5-hydroxy-1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
    Patent number: 11192877
    Abstract: The present disclosure provides a compound of Formula (I?): or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, stereoisomer, or tautomer thereof, wherein Rx, X1, X2, and R1 are as defined herein, and methods of making and using same.
    Type: Grant
    Filed: July 8, 2019
    Date of Patent: December 7, 2021
    Assignee: Novartis AG
    Inventors: Claire Adcock, Simone Bonazzi, Artiom Cernijenko, Philip Lam, Kathryn Taylor Linkens, Hasnain Ahmed Malik, Noel Marie-France Thomsen, Michael Scott Visser
  • SIGMA RECEPTOR BINDERS
    Publication number: 20210300903
    Abstract: Provided herein, inter alia, are compounds and methods of treating diseases including cancer, neurological disease, alcohol withdrawal, depression and anxiety, and neuropathic pain.
    Type: Application
    Filed: February 25, 2021
    Publication date: September 30, 2021
    Inventors: Stephen F. MARTIN, James J. SAHN, Kathryn Taylor LINKENS
  • Sigma receptor binders
    Patent number: 10954217
    Abstract: Provided herein, inter alia, are compounds and methods of treating diseases including cancer, neurological disease, alcohol withdrawal, depression and anxiety, and neuropathic pain.
    Type: Grant
    Filed: April 29, 2017
    Date of Patent: March 23, 2021
    Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Stephen F. Martin, James J. Sahn, Kathryn Taylor Linkens
  • 3-(5-HYDROXY-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND USES THEREOF
    Publication number: 20200017461
    Abstract: The present disclosure provides a compound of Formula (I?): or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, stereoisomer, or tautomer thereof, wherein Rx, X1, X2, and R1 are as defined herein, and methods of making and using same.
    Type: Application
    Filed: July 8, 2019
    Publication date: January 16, 2020
    Inventors: Claire ADCOCK, Simone BONAZZI, Artiom CERNIJENKO, Philip LAM, Kathryn Taylor LINKENS, Hasnain Ahmed MALIK, Noel Marie-France THOMSEN, Michael Scott VISSER
  • SIGMA RECEPTOR BINDERS
    Publication number: 20190177301
    Abstract: Provided herein, inter alia, are compounds and methods of treating diseases including cancer, neurological disease, alcohol withdrawal, depression and anxiety, and neuropathic pain.
    Type: Application
    Filed: April 29, 2017
    Publication date: June 13, 2019
    Inventors: Stephen F. MARTIN, James J. SAHN, Kathryn Taylor LINKENS